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==Overview== | ==Overview== | ||
Hypopituitarism was first described by Dr. Simmonds for the first time in 1914. Dr. Yalow and Berson discovered the [[radioimmunoassay]] in 1950. Causes of the hypopituitarism were being described through the 20th and 21st centuries. | |||
==Historical Perspective== | ==Historical Perspective== |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Hypopituitarism was first described by Dr. Simmonds for the first time in 1914. Dr. Yalow and Berson discovered the radioimmunoassay in 1950. Causes of the hypopituitarism were being described through the 20th and 21st centuries.
Historical Perspective
- In 1914, Dr. Simmonds was the first one to describe the hypopituitarism. He described it as the inability of the pituitary gland to secrete hormones matching the organs need.[1]
- In 1950, Dr. Yalow and Berson discovered the radioimmunoassay which helped in the measurement of the pituitary hormones after the diagnosis was only based on the signs and symptoms presented by the patients.[2]
- In 1973, combined stimulation tests of the hormones insulin, GnRH, and TRH were performed for the first time to assess the pituitary gland function.[3]
- Through the 20th and 21st centuries, causes of the hypopituitarism were being described.
References
- ↑ Schneider HJ, Aimaretti G, Kreitschmann-Andermahr I, Stalla GK, Ghigo E (2007). "Hypopituitarism". Lancet. 369 (9571): 1461–70. doi:10.1016/S0140-6736(07)60673-4. PMID 17467517.
- ↑ Prozesky OW (1979). "Measles vaccination". S Afr Med J. 55 (7): 236. PMID 441860.
- ↑ Harsoulis P, Marshall JC, Kuku SF, Burke CW, London DR, Fraser TR (1973). "Combined test for assessment of anterior pituitary function". Br Med J. 4 (5888): 326–9. PMC 1587416. PMID 4202260.