Adrenocortical carcinoma risk factors: Difference between revisions
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{{CMG}} {{AE}} {{AAM}} | {{CMG}} {{AE}} {{AAM}} | ||
==Overview== | ==Overview== | ||
The most potent risk factors in the development of adrenocortical cancer are [[ | The most potent risk factors in the development of adrenocortical cancer are [[Lynch syndrome]][[Beckwith-Wiedemann syndrome|, Beckwith-Wiedemann syndrome,]] [[Carney complex|Carney complex,]] [[Neurofibromatosis type I|Neurofibromatosis type 1,]] [[Multiple endocrine neoplasia type 1]] ([[MEN1]]), and [[Carney complex]]. | ||
==Risk Factors== | ==Risk Factors== | ||
Risk factor associated with adrenocortical carcinoma are: | Risk factor associated with adrenocortical carcinoma are: | ||
* Lynch syndrome | * [[Lynch syndrome]] | ||
*[[Beckwith-Wiedemann syndrome]] | *[[Beckwith-Wiedemann syndrome]] | ||
*[[Carney complex]] | *[[Carney complex]] | ||
*Neurofibromatosis type 1 | *[[Neurofibromatosis type I|Neurofibromatosis type 1]] | ||
*MEN1 | *[[Multiple endocrine neoplasia type 1]] ([[MEN1]]) | ||
{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" align="center" | {| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" align="center" | ||
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! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|Clinical picture}} | ! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|Clinical picture}} | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |Lynch syndrome | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |[[Lynch syndrome]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* MSH2, MSH6, MLH1, PMS2 | * [[MSH2]], [[MSH6]], [[MLH1]], [[PMS2]] | ||
| | | | ||
* Colorectal cancer | * [[Colorectal cancer]] | ||
* Endometrial cancer | * [[Endometrial cancer]] | ||
* Sebaceous neoplasms | * [[Sebaceous gland carcinoma|Sebaceous neoplasms]] | ||
* Ovarian cancer | * [[Ovarian cancer]] | ||
* Pancreatic cancer | * [[Pancreatic cancer]] | ||
* Brain cancer | * [[Brain cancer]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |Neurofibromatosis | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |[[Neurofibromatosis type I|Neurofibromatosis type 1]] | ||
type 1 | |||
| | | | ||
* NF1 | * [[NF1]] | ||
| | | | ||
* Malignant peripheral nerve sheet tumor | * [[Malignant]] [[Peripheral nervous system|peripheral nerve]] [[Nerve sheath|sheet]] [[tumor]] | ||
* Pheochromocytoma | * [[Pheochromocytoma]] | ||
* Café au lait spots | * [[Café au lait spot|Café au lait spots]] | ||
* Neurofibroma | * [[Neurofibroma]] | ||
* Optic glioma | * [[Optic nerve glioma|Optic glioma]] | ||
* Lisch nodule | * [[Lisch nodule]] | ||
* Skeletal abnormalities | * Skeletal abnormalities | ||
|- | |- | ||
|'''MEN1 | | '''[[Multiple endocrine neoplasia type 1|MEN1]]''' | ||
| | | | ||
* MENIN | * MENIN | ||
| | | | ||
* Foregut neuroendocrine tumors | * [[Foregut]] [[neuroendocrine tumors]] | ||
* Pituitary tumors | * [[Pituitary tumors]] | ||
* Parathyroid hyperplasia | * [[Parathyroid gland|Parathyroid]] [[hyperplasia]] | ||
* Collagenoma | * Collagenoma | ||
* Angiofibroma | * [[Angiofibroma]] | ||
* Adrenal adenoma/hyperplasia | * [[Adrenal adenoma]]/[[hyperplasia]] | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |Carney complex | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |[[Carney complex]] | ||
| | | | ||
* PRKAR1A | * [[PRKAR1A]] | ||
| | | | ||
* | * [[Adrenal disease]] | ||
* [[Sertoli cell]] [[tumors]] | |||
* | * [[Thyroid adenoma]] | ||
* Thyroid adenoma | * [[Myxoma]] | ||
* Myxoma | * [[Somatotrope|Somatotroph]] [[pituitary adenoma]] | ||
* Somatotroph pituitary adenoma | |||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |BWS | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" |[[BWS]] | ||
| | | | ||
* IGF2, CDKN1C, H19 | * [[IGF2]], [[CDKN1C]], [[H19 (gene)|H19]] | ||
| | | | ||
* | * [[Wilm's tumor|Wilm’s tumor]] | ||
* Hepatoblastoma | * [[Hepatoblastoma]] | ||
* Macrosomia | * [[Macrosomia]] | ||
* Adrenocortical cytomegaly | * [[Adrenocortical]] cytomegaly | ||
* Adrenal adenoma | * [[Adrenal adenoma]] | ||
* Adrenal cyst | * [[Adrenal Gland|Adrenal]] [[cyst]] | ||
* Hemihypertrophy | * [[Hemihypertrophy]] | ||
* Macroglossia | * [[Macroglossia]] | ||
* Omphalocele | * [[Omphalocele]] | ||
|} | |} | ||
Revision as of 15:43, 25 September 2017
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Adrenocortical carcinoma Microchapters |
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Differentiating Adrenocortical carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Study |
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Adrenocortical carcinoma risk factors On the Web |
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American Roentgen Ray Society Images of Adrenocortical carcinoma risk factors |
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Risk calculators and risk factors for Adrenocortical carcinoma risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
The most potent risk factors in the development of adrenocortical cancer are Lynch syndrome, Beckwith-Wiedemann syndrome, Carney complex, Neurofibromatosis type 1, Multiple endocrine neoplasia type 1 (MEN1), and Carney complex.
Risk Factors
Risk factor associated with adrenocortical carcinoma are:
- Lynch syndrome
- Beckwith-Wiedemann syndrome
- Carney complex
- Neurofibromatosis type 1
- Multiple endocrine neoplasia type 1 (MEN1)
| Differential Diagnosis | Gene mutations | Clinical picture |
|---|---|---|
| Lynch syndrome | ||
| Neurofibromatosis type 1 |
| |
| MEN1 |
|
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| Carney complex | ||
| BWS |