Autoimmune polyendocrine syndrome primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no established measures for the primary prevention of [disease name].

OR

There are no available vaccines against [disease name].

OR

Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].

OR

[Vaccine name] vaccine is recommended for [patient population] to prevent [disease name]. Other primary prevention strategies include [strategy 1], [strategy 2], and [strategy 3].

Primary Prevention

• There are no established measures for the primary prevention of [disease name].
• There are no available vaccines against [disease name].

OR

• Effective measures for the primary prevention of autoimmune polyendocrine syndrome (APS) include:
  • Patient education: Autoimmune polyendocrine syndrome may be inherited in autosomal recessive (APS type 1), autosomal dominant (APS type 2) or X linked fashion (APS type 3) and therefore educating relatives about presence of APS in family is necessary.
  • Screening should be done for first degree relatives of patients with APS for auto-antibodies against 21- hydroxylase, 17-hydroxylase, thyroid peroxidase, parietal cell, anti-intrinsic factor and islet cell antibodies.
  • Currently, there is not enough evidence to define optimal intervals for testing but data suggests that autoantibodies can develop at any age. Hence, we rescreen patients for autoantibodies even if their initial autoantibody tests are negative.