Sandbox:ap: Difference between revisions
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!Clinical features | !Clinical features | ||
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| | |Autoimmune | ||
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| rowspan="2" |Autosomal dominant | | rowspan="2" |Autosomal dominant | ||
|PTH gene | |PTH gene | ||
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|[[GCM2]] gene | |[[GCM2]] gene | ||
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|Autosomal dominant hypercalcemia | |Autosomal dominant hypercalcemia | ||
|Autosomal dominant hypocalcemia type 1 | |Autosomal dominant hypocalcemia type 1 | ||
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| rowspan="6" |Congenital multisystem syndromes | | rowspan="6" |Congenital multisystem syndromes | ||
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|'''[[DiGeorge syndrome]]''' | |'''[[DiGeorge syndrome]]''' | ||
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|'''[[CHARGE syndrome]]''' | |'''[[CHARGE syndrome]]''' | ||
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|'''Kenny-Caffey syndrome type 1''' | |'''Kenny-Caffey syndrome type 1''' | ||
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|'''Kenny-Caffey syndrome type 2''' | |'''Kenny-Caffey syndrome type 2''' | ||
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|'''Sanjad-Sakati syndrome''' | |'''Sanjad-Sakati syndrome''' | ||
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|'''[[Barakat syndrome]]''' | |'''[[Barakat syndrome]]''' | ||
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| rowspan="6" |Metabolic diseases | | rowspan="6" |Metabolic diseases | ||
| rowspan="2" |Mitochondiral polyneuropathies | | rowspan="2" |Mitochondiral polyneuropathies | ||
|Kearns–Sayre syndrome | |Kearns–Sayre syndrome | ||
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| rowspan="2" |Mitochondrial enzyme deficiencies | | rowspan="2" |Mitochondrial enzyme deficiencies | ||
|Mitochondrial trifunctional protein deficiency (MTP deficiency) | |Mitochondrial trifunctional protein deficiency (MTP deficiency) | ||
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|Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency (LCHAD deficiency) | |Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency (LCHAD deficiency) | ||
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| rowspan="2" |Heavy metal storage disorders | | rowspan="2" |Heavy metal storage disorders | ||
|Hemochromatosis | |Hemochromatosis | ||
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|Wilson's disease | |Wilson's disease | ||
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Revision as of 17:46, 29 September 2017
Hypercalcemia | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Related to Parathyroid gland | Unrelated to parathyroid gland | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Primary hyperparathyroidism | Secondary hyperparathyroidism | Tertiary hyperparathyroidism | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Typical primary hyperparathyroidism | Familial hypocalciuric hypercalcemia | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Malignancy | Medication induced | Nutritional | Granulomatous disease | Surgical | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Para-neoplastic syndrome: Parathyroid hormone related peptide | Metaplasia: Hypercalcemia due to bone destruction | Thiazide diuretics | Lithium | Milk alkali syndrome | Vitamin D toxicity | Sarcoidosis | Immobilization | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Differential diagnosis
Hypoparathyroidism | Inheritance | Gene mutation | Clinical features | |||
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Autoimmune | ||||||
Isolated | Familial Isolated hypoparathyroidism | Autosomal dominant | PTH gene | |||
GCM2 gene | ||||||
Autosomal recessive | PTH gene | |||||
GCM2 gene | ||||||
X-linked | ||||||
Autosomal dominant hypercalcemia | Autosomal dominant hypocalcemia type 1 | |||||
Autosomal dominant hypocalcemia type 2 | ||||||
Congenital multisystem syndromes | DiGeorge syndrome | |||||
CHARGE syndrome | ||||||
Kenny-Caffey syndrome type 1 | ||||||
Kenny-Caffey syndrome type 2 | ||||||
Sanjad-Sakati syndrome | ||||||
Barakat syndrome | ||||||
Metabolic diseases | Mitochondiral polyneuropathies | Kearns–Sayre syndrome | ||||
Maternally inherited diabetes and deafness (MIDD) | ||||||
Mitochondrial enzyme deficiencies | Mitochondrial trifunctional protein deficiency (MTP deficiency) | |||||
Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency (LCHAD deficiency) | ||||||
Heavy metal storage disorders | Hemochromatosis | |||||
Wilson's disease |