Hemolytic anemia risk factors: Difference between revisions

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==Risk Factors==
==Risk Factors==
Oxidative stress in the setting of G6PD deficiency:<ref name="pmid24372186">{{cite journal| author=Luzzatto L, Seneca E| title=G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications. | journal=Br J Haematol | year= 2014 | volume= 164 | issue= 4 | pages= 469-80 | pmid=24372186 | doi=10.1111/bjh.12665 | pmc=4153881 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24372186  }} </ref>
'''Oxidative stress in the setting of G6PD deficiency''':<ref name="pmid24372186">{{cite journal| author=Luzzatto L, Seneca E| title=G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications. | journal=Br J Haematol | year= 2014 | volume= 164 | issue= 4 | pages= 469-80 | pmid=24372186 | doi=10.1111/bjh.12665 | pmc=4153881 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24372186  }} </ref>
*Use of primiquine for malaria treatment
*Use of primiquine for malaria treatment
*Use of dapsone for PCP or leprosy treatment
*Use of dapsone for PCP or leprosy treatment
Line 16: Line 16:
*Use of nitrofurantoin for treatment of a urinary tract infection
*Use of nitrofurantoin for treatment of a urinary tract infection


Cardiovascular surgery-related risk factors:
'''Cardiovascular surgery-related risk factors''':
*Presence of a mechanical mitral or aortic valve
*Presence of a mechanical mitral or aortic valve
*High shear stress from ECMO circuit
*High shear stress from ECMO circuit


Genetic conditions:
'''Genetic conditions''':
*Hereditary spherocytosis
*Hereditary spherocytosis
*Hereditary elliptocytosis
*Hereditary elliptocytosis

Revision as of 06:57, 5 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Risk Factors

Oxidative stress in the setting of G6PD deficiency:[1]

  • Use of primiquine for malaria treatment
  • Use of dapsone for PCP or leprosy treatment
  • Consumption of fava beans as part of a Mediterranean diet
  • Use of sulfa drugs like trimethoprim-sulfamethoxazole for treatment of skin, urinary tract, or other infections
  • Use of phenazopyridine for alleviating symptoms of dysuria
  • Use of nitrofurantoin for treatment of a urinary tract infection

Cardiovascular surgery-related risk factors:

  • Presence of a mechanical mitral or aortic valve
  • High shear stress from ECMO circuit

Genetic conditions:

  • Hereditary spherocytosis
  • Hereditary elliptocytosis

References

  1. Luzzatto L, Seneca E (2014). "G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications". Br J Haematol. 164 (4): 469–80. doi:10.1111/bjh.12665. PMC 4153881. PMID 24372186.

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