Myxedema coma history and symptoms: Difference between revisions
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* Thyroid hormone therapy that was inappropriately discontinued | * Thyroid hormone therapy that was inappropriately discontinued | ||
==Symptoms== | ==Symptoms== | ||
The function of all organ systems and various metabolic pathways are compromised in hypothyroidism. The cardinal symptoms of myxedema coma are the sensory impairment and hypothermia. The accumulation in the interstitial tissue of mucopolysaccharides and water leads to myxedema that compromises large part of the tissues. | |||
Symptoms of myxedema coma can be summarized in the following table:<ref name="pmid17127141">{{cite journal |vauthors=Wartofsky L |title=Myxedema coma |journal=Endocrinol. Metab. Clin. North Am. |volume=35 |issue=4 |pages=687–98, vii–viii |year=2006 |pmid=17127141 |doi=10.1016/j.ecl.2006.09.003 |url=}}</ref> | Symptoms of myxedema coma can be summarized in the following table:<ref name="pmid17127141">{{cite journal |vauthors=Wartofsky L |title=Myxedema coma |journal=Endocrinol. Metab. Clin. North Am. |volume=35 |issue=4 |pages=687–98, vii–viii |year=2006 |pmid=17127141 |doi=10.1016/j.ecl.2006.09.003 |url=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
History
- History of thyroid disease
- History of radioiodine therapy or thyroidectomy,
- Thyroid hormone therapy that was inappropriately discontinued
Symptoms
The function of all organ systems and various metabolic pathways are compromised in hypothyroidism. The cardinal symptoms of myxedema coma are the sensory impairment and hypothermia. The accumulation in the interstitial tissue of mucopolysaccharides and water leads to myxedema that compromises large part of the tissues. Symptoms of myxedema coma can be summarized in the following table:[1]
| Organ system involved | Manifestations |
|---|---|
| CNS |
|
| Cardiovascular |
|
| Pulmonary | |
| Gastro-intestinal |
|
| Renal and electrolyte |
|
| Systemic | Presence of normal temperature in myxedema
indicates presence of infection |
References
- ↑ Wartofsky L (2006). "Myxedema coma". Endocrinol. Metab. Clin. North Am. 35 (4): 687–98, vii–viii. doi:10.1016/j.ecl.2006.09.003. PMID 17127141.