Myxedema coma history and symptoms: Difference between revisions
Aditya Ganti (talk | contribs) |
Aditya Ganti (talk | contribs) |
||
| Line 21: | Line 21: | ||
* Cognitive dysfunction | * Cognitive dysfunction | ||
* Depression | * Depression | ||
* Psychosis | * Psychosis | ||
* Hypothermia | * Hypothermia | ||
| Line 30: | Line 29: | ||
* SOB | * SOB | ||
* Chest pain | * Chest pain | ||
* Palpitations | |||
* Orthopnea | |||
* PND | |||
* Edema | |||
|- | |- | ||
|Pulmonary | |Pulmonary | ||
| Line 45: | Line 49: | ||
|- | |- | ||
|Systemic | |Systemic | ||
| | | | ||
*Sweats | |||
*Anorexia | |||
*Weakness | |||
*Sleep disturbances | |||
|} | |} | ||
===Myxedema=== | ===Myxedema=== | ||
Revision as of 07:27, 10 October 2017
|
Myxedema coma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Myxedema coma history and symptoms On the Web |
|
American Roentgen Ray Society Images of Myxedema coma history and symptoms |
|
Risk calculators and risk factors for Myxedema coma history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
History
- History of thyroid disease
- History of radioiodine therapy or thyroidectomy,
- Thyroid hormone therapy that was inappropriately discontinued
Symptoms
The function of all organ systems and various metabolic pathways are compromised in hypothyroidism. The cardinal symptoms of myxedema coma are the sensory impairment and hypothermia. The accumulation in the interstitial tissue of mucopolysaccharides and water leads to myxedema that compromises large part of the tissues. Symptoms of myxedema coma can be summarized in the following table:[1]
| Organ system involved | Manifestations |
|---|---|
| CNS |
|
| Cardiovascular |
|
| Pulmonary | |
| Gastro-intestinal |
|
| Renal and electrolyte |
|
| Systemic |
|
Myxedema
- Myxedema is a defined as deposition of mucopolysaccharides in the dermis at periorbital level and is responsible for the typical bloated facies.
- It is accompanied by thin, dry and brittle hair and even alopecia, loss of the tail of the eyebrows (sign of Queen Anne or supraciliar madarosis) and macroglossia, with cold skin (by reflex cutaneous vasoconstriction), pale-yellowish (from anemia and hypercarotinemia), dry, rough and rough (elephant skin).
Hypothermia
- It is defined by the presence of core body temperature (rectal) <35 ° C, although in general it is serious, with records between 26 ° C and 32 ° C.
- It is noted in most cases of myxedema coma, and due to a decrease in thermogenesis accompanying the decline of metabolism.
- Hypoglycemia also complicates hypothermia.
- There is a correlation between the degree of hypothermia and survival, with a worse prognosis for those with temperatures below 32 ° .
- Occasionally, hypothermia may be absent in presence of serious infections. Thus, the diagnosis must be seriously considered in every afebrile patient with a serious underlying infection.
References
- ↑ Wartofsky L (2006). "Myxedema coma". Endocrinol. Metab. Clin. North Am. 35 (4): 687–98, vii–viii. doi:10.1016/j.ecl.2006.09.003. PMID 17127141.