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*In 1926, Wilder-et-al associated [[hyperinsulinism]] and functional islet tumor after a surgery on a person who had [[hypoglycemia]] and found an [[Islet cell carcinoma|islet cell cancer]] with [[liver]] metastasis.<ref name="WilderAllan1927">{{cite journal|last1=Wilder|first1=Russell M.|last2=Allan|first2=Frank N.|last3=Power|first3=M. H.|last4=Robertson|first4=H. E.|title=CARCINOMA OF THE ISLANDS OF THE PANCREAS|journal=Journal of the American Medical Association|volume=89|issue=5|year=1927|pages=348|issn=0002-9955|doi=10.1001/jama.1927.02690050014007}}</ref> | *In 1926, Wilder-et-al associated [[hyperinsulinism]] and functional islet tumor after a surgery on a person who had [[hypoglycemia]] and found an [[Islet cell carcinoma|islet cell cancer]] with [[liver]] metastasis.<ref name="WilderAllan1927">{{cite journal|last1=Wilder|first1=Russell M.|last2=Allan|first2=Frank N.|last3=Power|first3=M. H.|last4=Robertson|first4=H. E.|title=CARCINOMA OF THE ISLANDS OF THE PANCREAS|journal=Journal of the American Medical Association|volume=89|issue=5|year=1927|pages=348|issn=0002-9955|doi=10.1001/jama.1927.02690050014007}}</ref> | ||
*In 1927, William J Mayo was the first to discover the association between [[hyperinsulinism]] and a functional [[Pancreatic islet cell tumors|pancreatic islet cell tumor]]. In 1927 the insulinoma was first described in Mayo clinic which was dissected in 1929 in Toronto.<ref name="pmid20187464">{{cite journal| author=Stamatakos M, Safioleas C, Tsaknaki S, Safioleas P, Iannescu R, Safioleas M| title=Insulinoma: a rare neuroendocrine pancreatic tumor. | journal=Chirurgia (Bucur) | year= 2009 | volume= 104 | issue= 6 | pages= 669-73 | pmid=20187464 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20187464 }} </ref> | *In 1927, William J Mayo was the first to discover the association between [[hyperinsulinism]] and a functional [[Pancreatic islet cell tumors|pancreatic islet cell tumor]]. In 1927, the insulinoma was first described in Mayo clinic, which was dissected in 1929 in Toronto.<ref name="pmid20187464">{{cite journal| author=Stamatakos M, Safioleas C, Tsaknaki S, Safioleas P, Iannescu R, Safioleas M| title=Insulinoma: a rare neuroendocrine pancreatic tumor. | journal=Chirurgia (Bucur) | year= 2009 | volume= 104 | issue= 6 | pages= 669-73 | pmid=20187464 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20187464 }} </ref> | ||
*In 1929, the first surgical cure was performed by Roscoe Graham.<ref name="pmid17856569">{{cite journal |vauthors=Whipple AO, Frantz VK |title=ADENOMA OF ISLET CELLS WITH HYPERINSULINISM: A REVIEW |journal=Ann. Surg. |volume=101 |issue=6 |pages=1299–335 |year=1935 |pmid=17856569 |pmc=1390871 |doi= |url=}}</ref> | *In 1929, the first surgical cure was performed by Roscoe Graham.<ref name="pmid17856569">{{cite journal |vauthors=Whipple AO, Frantz VK |title=ADENOMA OF ISLET CELLS WITH HYPERINSULINISM: A REVIEW |journal=Ann. Surg. |volume=101 |issue=6 |pages=1299–335 |year=1935 |pmid=17856569 |pmc=1390871 |doi= |url=}}</ref> | ||
Revision as of 18:06, 13 October 2017
Historical Perspective
Discovery
- In 1869, Paul Langerhans first described pancreatic islet cells, when he was still a medical student.
- In 1902, Nicholls discovered the first adenoma of pancreatic islets.[1]
- In 1922, Frederick Banting and Charles Best were the first to discover insulin from a dog’s pancreas.
- In 1926, Wilder-et-al associated hyperinsulinism and functional islet tumor after a surgery on a person who had hypoglycemia and found an islet cell cancer with liver metastasis.[2]
- In 1927, William J Mayo was the first to discover the association between hyperinsulinism and a functional pancreatic islet cell tumor. In 1927, the insulinoma was first described in Mayo clinic, which was dissected in 1929 in Toronto.[1]
- In 1929, the first surgical cure was performed by Roscoe Graham.[3]
- In 1935, Whipple suggested a diagnostic criterion for the diagnosis of insulinoma called as Whipple's triad. [3]
References
- ↑ 1.0 1.1 Stamatakos M, Safioleas C, Tsaknaki S, Safioleas P, Iannescu R, Safioleas M (2009). "Insulinoma: a rare neuroendocrine pancreatic tumor". Chirurgia (Bucur). 104 (6): 669–73. PMID 20187464.
- ↑ Wilder, Russell M.; Allan, Frank N.; Power, M. H.; Robertson, H. E. (1927). "CARCINOMA OF THE ISLANDS OF THE PANCREAS". Journal of the American Medical Association. 89 (5): 348. doi:10.1001/jama.1927.02690050014007. ISSN 0002-9955.
- ↑ 3.0 3.1 Whipple AO, Frantz VK (1935). "ADENOMA OF ISLET CELLS WITH HYPERINSULINISM: A REVIEW". Ann. Surg. 101 (6): 1299–335. PMC 1390871. PMID 17856569.