Adrenocortical carcinoma classification: Difference between revisions
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===Histology:=== | ===Histology:=== | ||
Adrenocortical carcinoma can be classified according to the differentiation of the tissue under the microscope into | |||
* Well-differentiated | * Well-differentiated | ||
* Intermediate differentiated | * Intermediate differentiated |
Revision as of 14:16, 17 October 2017
Adrenocortical carcinoma Microchapters |
Differentiating Adrenocortical carcinoma from other Diseases |
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Adrenocortical carcinoma classification On the Web |
American Roentgen Ray Society Images of Adrenocortical carcinoma classification |
Risk calculators and risk factors for Adrenocortical carcinoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Ahmad Al Maradni, M.D. [3] Mohammed Abdelwahed M.D[4]
Overview
Adrenocortical carcinoma can be classified according to hormone production and histological appearance. ACC may secrete cortisol, aldosterone, testosterone or estrogen. Other variants include oncocytic adrenal cortical carcinoma, myxoid adrenal cortical carcinoma, and carcinosarcoma.
Classification
Adrenocortical carcinomas are classified depending on:[1]
Hormones production:
Functional
A Functional adrenocortical carcinoma may produce one or more of the following hormones:[2]
Nonfunctional
A nonfunctional adrenocortical carcinoma does not procuce any of the above hormones.
Histology:
Adrenocortical carcinoma can be classified according to the differentiation of the tissue under the microscope into
- Well-differentiated
- Intermediate differentiated
- Poorly differentiated
- Anaplastic
Variants
- Oncocytic adrenal cortical carcinoma
- Myxoid adrenal cortical carcinoma
- Carcinosarcoma
- Adenosquamous adrenocortical carcinoma
- Clear cell adrenal cortical carcinoma
References
- ↑ de Krijger RR, Papathomas TG (2012). "Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants". Virchows Arch. 460 (1): 9–18. doi:10.1007/s00428-011-1166-y. PMC 3267029. PMID 22086150.
- ↑ Ganeshan D, Bhosale P, Kundra V (2012). "Current update on cytogenetics, taxonomy, diagnosis, and management of adrenocortical carcinoma: what radiologists should know". AJR Am J Roentgenol. 199 (6): 1283–93. doi:10.2214/AJR.11.8282. PMID 23169720.