Whipple's disease classification: Difference between revisions
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{{familytree | | | | | | | E01 | | E02 | | E03 | | E04 | | E05 | | E06 | | E07 | | | | |E01=[[Heart]]|E02=[[CNS]]|E03=[[Eye]]|E04=[[Lung]]|E05=[[Bone]]|E06=[[Serosa]]|E07=[[Skin]]}} | {{familytree | | | | | | | E01 | | E02 | | E03 | | E04 | | E05 | | E06 | | E07 | | | | |E01=[[Heart]]|E02=[[CNS]]|E03=[[Eye]]|E04=[[Lung]]|E05=[[Bone]]|E06=[[Serosa]]|E07=[[Skin]]}} | ||
{{familytree | | | | | | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | | | |E01=[[Heart]]|E02=[[CNS]]|E03=[[Eye]]|E04=[[Lung]]|E05=[[Bone]]|E06=[[Serosa]]|E07=[[Skin]]}} | {{familytree | | | | | | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | | | |E01=[[Heart]]|E02=[[CNS]]|E03=[[Eye]]|E04=[[Lung]]|E05=[[Bone]]|E06=[[Serosa]]|E07=[[Skin]]}} | ||
{{familytree | | | | | | | E01 | | E02 | | E03 | | E04 | | E05 | | E06 | | E07 | | | | |E01=|E02=|E03=|E04=|E05=|E06=|E07=}} | {{familytree | | | | | | | E01 | | E02 | | E03 | | E04 | | E05 | | E06 | | E07 | | | | |E01= | ||
*Blood-culture negative endocarditis | |||
|E02= | |||
*Encephalitis | |||
*Progressive dementia | |||
*Cerebellar ataxia | |||
*Supranuclear ophthalmoplegia|E03=|E04=|E05=|E06=|E07=}} | |||
{{familytree/end}} | {{familytree/end}} | ||
Revision as of 03:12, 31 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
Whipple’s disease may be classified into 4 groups based on clinical manifestation: Acute infection, asymptomatic carrier state, the classic Whipple’s disease, and localized chronic infection.
Classification
- Whipple's disease may be classified to 2 groups of acute and chronic based on the duration.
- Whipple's disease may be classified to 2 groups of systemic and localized infection based on organ involvement.
- Tropheryma whipplei infection may be classified to 4 groups based on the clinical manifestation:[1][2]
- Acute infections such as:
- Asymptomatic carrier state
- The classic Whipple’s disease
- Localized involvement of different organs including:
Whipple's disease classification based on the duration
| Whipple's disease classification | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Acute | Chronic | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Gastroenteritis | Pneumonia | Bacteremia | Asymptomatic carrier state | Classic Whipple's disease | |||||||||||||||||||||||||||||||||||||||||||||||||||
Whipple's disease classification based on organ involvement
| Localized involvement | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Heart | CNS | Eye | Lung | Bone | Serosa | Skin | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| *Blood-culture negative endocarditis | *Encephalitis
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References
- ↑ Marth, Thomas (2009). "New Insights into Whipple's Disease – A Rare Intestinal Inflammatory Disorder". Digestive Diseases. 27 (4): 494–501. doi:10.1159/000233288. ISSN 1421-9875.
- ↑ Street, Sara; Donoghue, Helen D; Neild, GH (1999). "Tropheryma whippelii DNA in saliva of healthy people". The Lancet. 354 (9185): 1178–1179. doi:10.1016/S0140-6736(99)03065-2. ISSN 0140-6736.