Sandbox: TAVI - AUC: Difference between revisions

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- Truly severe AS  - High or intermediate surgical risk  
- Truly severe AS  - High or intermediate surgical risk  
| bgcolor="LightCoral" | R (1) || bgcolor="LightCoral" | R (3) || bgcolor="LightGreen" | A (8)
|| bgcolor="LightCoral" | R (1) || bgcolor="LightCoral" | R (3) || bgcolor="LightGreen" | A (8)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
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- Truly severe AS  - Low surgical risk  
- Truly severe AS  - Low surgical risk  
| bgcolor="LightCoral" | R (1) || bgcolor="LightCoral" | R (2) || bgcolor="LightGreen" | A (9)
|| bgcolor="LightCoral" | R (1) || bgcolor="LightCoral" | R (2) || bgcolor="LightGreen" | A (9)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
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- Pseudosevere AS  
- Pseudosevere AS  
| bgcolor="LightGreen" | A (8) || bgcolor="LightCoral" | R (2) || bgcolor="LightCoral" | R (2)
|| bgcolor="LightGreen" | A (8) || bgcolor="LightCoral" | R (2) || bgcolor="LightCoral" | R (2)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
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- Very calcified aortic valve on echo and/or CT, suggesting truly severe AS, or calculation of a projected valve area that remains severely reduced  - High or intermediate surgical risk  
- Very calcified aortic valve on echo and/or CT, suggesting truly severe AS, or calculation of a projected valve area that remains severely reduced  - High or intermediate surgical risk  
| bgcolor="LemonChiffon" | M (4) || bgcolor="LemonChiffon" | M (5) || bgcolor="LightGreen" | A (7)
|| bgcolor="LemonChiffon" | M (4) || bgcolor="LemonChiffon" | M (5) || bgcolor="LightGreen" | A (7)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
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- Minimal calcification on aortic valve on echo and/or CT  - High or intermediate surgical risk  
- Minimal calcification on aortic valve on echo and/or CT  - High or intermediate surgical risk  
| bgcolor="LightGreen" | A (7) || bgcolor="LightCoral" | R (3) || bgcolor="LightCoral" | R (2)
|| bgcolor="LightGreen" | A (7) || bgcolor="LightCoral" | R (3) || bgcolor="LightCoral" | R (2)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2)   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2)   
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- High or intermediate surgical risk  
- High or intermediate surgical risk  
| bgcolor="LightCoral" | R (3) || bgcolor="LemonChiffon" | M (4) || bgcolor="LightGreen" | A (7)
|| bgcolor="LightCoral" | R (3) || bgcolor="LemonChiffon" | M (4) || bgcolor="LightGreen" | A (7)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2)   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2)   
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- No flow reserve on low-dose dobutamine echo  - High or intermediate surgical risk  
- No flow reserve on low-dose dobutamine echo  - High or intermediate surgical risk  
| bgcolor="LightGreen" | A (7) || bgcolor="LemonChiffon" | M (4) || bgcolor="LightCoral" | R (3)
|| bgcolor="LightGreen" | A (7) || bgcolor="LemonChiffon" | M (4) || bgcolor="LightCoral" | R (3)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
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- Truly severe AS  - High or intermediate surgical risk  
- Truly severe AS  - High or intermediate surgical risk  
| bgcolor="LightCoral" | R (3) || bgcolor="LemonChiffon" | M (5) || bgcolor="LightGreen" | A (7)
|| bgcolor="LightCoral" | R (3) || bgcolor="LemonChiffon" | M (5) || bgcolor="LightGreen" | A (7)
|-  
|-  
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo   
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- Pseudosevere severe AS  - High or intermediate surgical risk  
- Pseudosevere severe AS  - High or intermediate surgical risk  
| bgcolor="LightGreen" | A (7) || bgcolor="LightCoral" | R (2) || bgcolor="LightCoral" | R (2)
|| bgcolor="LightGreen" | A (7) || bgcolor="LightCoral" | R (2) || bgcolor="LightCoral" | R (2)
|-  
|-  
| '''Preserved Ejection Fraction (≥50%)''' || || ||
| '''Preserved Ejection Fraction (≥50%)''' || || ||
|-
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Vmax ≥4 m/sec or mean gradient ≥40 mmHg on resting echo - Symptomatic - High or intermediate surgical risk || bgcolor="LightCoral" | R (1) || bgcolor="LightCoral" | R (2) || bgcolor="LightGreen" | A (9)
|-
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Vmax ≥4 m/sec or mean gradient ≥40 mmHg on resting echo - Symptomatic - Low surgical risk || bgcolor="LightCoral" | R (1) || bgcolor="LightCoral" | R (1) || bgcolor="LightGreen" | A (9)
|-
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Low flow - Low gradient - Symptomatic - Evidence of a severely calcified valve - Clinical, hemodynamic, and anatomic data support valve obstruction as the most likely cause of symptoms - High or intermediate surgical risk || bgcolor="LightCoral" | R (2) || bgcolor="LightCoral" | R (3) || bgcolor="LightGreen" | A (8)
|-
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Low flow - Low gradient - Symptomatic - Evidence of a severely calcified valve - Clinical, hemodynamic, and anatomic data support valve obstruction as the most likely cause of symptoms - Low surgical risk || R (1) || bgcolor="LightCoral" | R (1) || bgcolor="LightGreen" | A (9)
|-
| - AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Low flow - Low gradient - Evidence of a severely calcified valve - Asymptomatic - High or intermediate surgical risk || bgcolor="LemonChiffon" | M (6) || bgcolor="LightCoral" | R (3) || bgcolor="LemonChiffon" | M (4)
|}
|}

Revision as of 03:18, 1 November 2017


Template:TAVI - AUC Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Arzu Kalayci, M.D. [2]

ACC/AATS/AHA/ASE/EACTS/ HVS/SCA/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for the Treatment of Patients With Severe Aortic Stenosis

Asymptomatic, High-Gradient, Severe AS

Appropriate Use Median Score (1–9)

Indication No Intervention AVR (TAVR or SAVR)
- LVEF ≤50%

- Vmax 4.0–4.9 m/sec - Negative exercise stress test

- No predictors of symptom onset or of rapid progression (e.g., DVmax >0.3 m/s/y, severe valve calcification, elevated BNP, or excessive LV hypertrophy in the absence of hypertension) - High or intermediate surgical risk

A (7) M (5)
- LVEF ≤50%

- Vmax 4.0–4.9 m/sec - Negative exercise stress test

- No predictors of symptom onset or of rapid progression (e.g., DVmax >0.3 m/s/y, severe valve calcification, elevated BNP, or excessive LV hypertrophy in the absence of hypertension) - Low surgical risk

A (7) M (5)
- LVEF ≥50%

- Vmax 4.0–4.9 m/sec - High-risk profession (e.g., airline pilot) or lifestyle (e.g., competitive athlete) or anticipated prolonged time away from close medical supervision

- Low surgical risk

M (4) A (7)
- LVEF ≥50%

- Vmax 4.0–4.9 m/sec - High-risk profession (e.g., airline pilot) or lifestyle (e.g., competitive athlete) or anticipated prolonged time away from close medical supervision

- Low surgical risk

M (4) A (7)
- LVEF ≥50%

- Vmax 4.0–4.9 m/sec - Negative exercise stress test

- ≥1 predictor(s) of symptom onset or of rapid progression (e.g., DVmax >0.3 m/s/y, severe valve calcification, elevated BNP, or excessive LV hypertrophy in the absence of hypertension) - High or intermediate surgical risk

M (4) A (7)
- LVEF ≥50%

- Vmax 4.0–4.9 m/sec - Negative exercise stress test

- ≥1 predictor(s) of symptom onset or of rapid progression (e.g., DVmax >0.3 m/s/y, severe valve calcification, elevated BNP, or excessive LV hypertrophy in the absence of hypertension) - Low surgical risk

M (4) A (8)
- LVEF ≥50% - Vmax 4.0–4.9 m/sec

- Abnormal exercise stress test - High or intermediate surgical risk

R (3) A (8)
- LVEF ≥50%

- Vmax 4.0–4.9 m/sec - Abnormal exercise stress test

- Low surgical risk

R (2) A (8)
- LVEF ≥50%

- Very severe AS (Vmax ≥5 m/sec or mean gradient ≥60 mmHg) - High or intermediate surgical risk

M (4) A (7)
- LVEF ≥50%

- Very severe AS (Vmax ≥5 m/sec or mean gradient ≥60 mmHg) - Low surgical risk

R (2) A (8)
- LVEF <50%

- Very severe AS (Vmax ≥4 m/sec or mean gradient ≥40 mmHg) - High or intermediate surgical risk

R (2) A (8)
- LVEF <50%

- Very severe AS (Vmax ≥4 m/sec or mean gradient ≥40 mmHg) - Low surgical risk

R (1) A (9)
- Undergoing another cardiac surgery or ascending aortic surgery R (1) A (9)
A = Appropriate; AS = aortic stenosis; AVR = aortic valve replacement; BNP = b-type natriuretic peptide; LV = left ventricular/left ventricle; LVEF = left ventricular ejection fraction; M = May Be Appropriate; R = Rarely Appropriate; SAVR = surgical aortic valve replacement; TAVR = transcatheter aortic valve replacement; Vmax = peak aortic valve velocity.

Flow, Gradient and Ejection Fraction

Appropriate Use Median Score (1–9)

Indication No Intervention BAV (as Bridge to Decision) AVR (TAVR or SAVR)
Reduced Ejection Fraction (<50%)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF 20% to 49% - Low flow

- Low gradient - Flow reserve on low-dose dobutamine echo

- Truly severe AS - High or intermediate surgical risk

bgcolor="LightCoral" | R (1) R (3) A (8)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF 20% to 49% - Low flow

- Low gradient - Flow reserve on low-dose dobutamine echo

- Truly severe AS - Low surgical risk

bgcolor="LightCoral" | R (1) R (2) A (9)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF 20% to 49% - Low flow

- Low gradient - Flow reserve on low-dose dobutamine echo

- Pseudosevere AS

bgcolor="LightGreen" | A (8) R (2) R (2)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF 20% to 49% - Low flow

- Low gradient - No flow reserve on low-dose dobutamine echo

- Very calcified aortic valve on echo and/or CT, suggesting truly severe AS, or calculation of a projected valve area that remains severely reduced - High or intermediate surgical risk

bgcolor="LemonChiffon" | M (4) M (5) A (7)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF 20% to 49% - Low flow

- Low gradient - No flow reserve on low-dose dobutamine echo

- Minimal calcification on aortic valve on echo and/or CT - High or intermediate surgical risk

bgcolor="LightGreen" | A (7) R (3) R (2)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2)

- LVEF <20% - Vmax ≥4 m/sec or mean gradient ≥40 mmHg on resting echo

- High or intermediate surgical risk

bgcolor="LightCoral" | R (3) M (4) A (7)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2)

- LVEF <20% - Mean gradient <20 mmHg on resting echo

- No flow reserve on low-dose dobutamine echo - High or intermediate surgical risk

bgcolor="LightGreen" | A (7) M (4) R (3)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF <20% - Low flow

- Low gradient - Flow reserve on low-dose dobutamine echo

- Truly severe AS - High or intermediate surgical risk

bgcolor="LightCoral" | R (3) M (5) A (7)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) on resting echo

- LVEF <20% - Low flow

- Low gradient - Flow reserve on low-dose dobutamine echo

- Pseudosevere severe AS - High or intermediate surgical risk

bgcolor="LightGreen" | A (7) R (2) R (2)
Preserved Ejection Fraction (≥50%)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Vmax ≥4 m/sec or mean gradient ≥40 mmHg on resting echo - Symptomatic - High or intermediate surgical risk R (1) R (2) A (9)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Vmax ≥4 m/sec or mean gradient ≥40 mmHg on resting echo - Symptomatic - Low surgical risk R (1) R (1) A (9)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Low flow - Low gradient - Symptomatic - Evidence of a severely calcified valve - Clinical, hemodynamic, and anatomic data support valve obstruction as the most likely cause of symptoms - High or intermediate surgical risk R (2) R (3) A (8)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Low flow - Low gradient - Symptomatic - Evidence of a severely calcified valve - Clinical, hemodynamic, and anatomic data support valve obstruction as the most likely cause of symptoms - Low surgical risk R (1) R (1) A (9)
- AVA ≤1.0 cm2 (or indexed AVA ≤0.6 cm2/m2) - Low flow - Low gradient - Evidence of a severely calcified valve - Asymptomatic - High or intermediate surgical risk M (6) R (3) M (4)