Chronic pancreatitis differential diagnosis

Chronic pancreatitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Differentiating Chronic Pancreatitis from Other Diseases

Disease	Clinical feature			Laboratory findings	Imaging findings
	Fever	Weight loss	Abdominal pain
Chronic pancreatitis		✔	✔	DM type II, amylase and lipase levels may be slightly elevated
Ampullary carcinoma
Cholangitis
Cholecystitis
Chronic gastritis
Community-Acquired Pneumonia (CAP)
Intestinal perforation
Crohn disease
Myocardial infarction
Mesenteric artery ischemia
Pancreatic cancer
Peptic ulcer disease
Retroperitoneal hematoma			✔	Anemia	MRI is the best radiologic tool to differentiate between retroperitoneal masses.
Retroperitoneal abscess	✔		✔	Leukocytosis, positive inflammatory markers
Retroperitoneal tumors (.e.g. liposarcoma)	✔	✔	✔	positive tumor marker

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