Erythroplasia of Queyrat

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Synonyms and keywords: EQ

Overview

Erythroplasia of Queyrat was named after Louis Queyrat, a French dermatologist who was head of the dermatology service of l'Hôpital Ricord, a venereal hospital in Paris, now Hôpital Cochin. The pathogenesis of Erythroplasia of Queyrat is characterized by squamous cell carcinoma in situ of the glans penis. Erythroplasia of Queyrat is more commonly observed among patients aged 40 years old. The most common risk factor in the development of Erythroplasia of Queyrat is an uncircumcised penis. The mainstay of therapy for Erythroplasia of Queyrat is imiquimod or 5-fluorouracil for several weeks to months.

Historical Perspective

• Erythroplasia of Queyrat was named after Louis Queyrat, a French dermatologist who was head of the dermatology service of l'Hôpital Ricord, a venereal hospital in Paris, now Hôpital Cochin.

Pathophysiology

• The pathogenesis of Erythroplasia of Queyrat is characterized by squamous cell carcinoma in situ of the glans penis

Epidemiology and Demographics

Age

• Erythroplasia of Queyrat is more commonly observed among patients aged 40 years old.

Gender

• Males are affected with Erythroplasia of Queyrat.

Risk Factors

• Most common risk factor in the development of Erythroplasia of Queyrat is uncircumcised penis.

Diagnosis

Symptoms

• Symptoms of Erythroplasia of Queyrat may include the following:

• Red rash on the tip of the penis
• Irritation on the tip of the penis

Imaging Findings

• There are no imaging study findings associated with Erythroplasia of Queyrat.

Treatment

Medical Therapy

• The mainstay of therapy for Erythroplasia of Queyrat is imiquimod or 5-fluorouracil for several weeks to months.

Surgery

• Microscopic shaving (Mohs surgery) can be performed for patients with aggressive forms of Erythroplasia of Queyrat.