Budd-Chiari syndrome risk factors: Difference between revisions

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==Risk Factors==
==Risk Factors==
* Estrogen-containing (combined) forms of [[hormonal contraception]]
*Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder.Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome.
* [[Pregnancy]]
Associated risk factors include:
* [[Paroxysmal nocturnal hemoglobinuria]]<ref>Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history of paroxysmal nocturnal hemoglobinuria. N Engl J Med. 1995 Nov 9;333(19):1253-8.</ref> and 12% may acquire Budd-Chiari. <ref>Socie G, Mary JY, de Gramont A, Rio B, Leporrier M, Rose C, Heudier P, Rochant H, Cahn JY, Gluckman E. Paroxysmal nocturnal haemoglobinuria: long-term follow-up and prognostic factors. French Society of Haematology. Lancet. 1996 Aug 31;348(9027):573-7. </ref>
*Hematologic disorders including:
**Polycythemia rubra vera
**Paroxysmal nocturnal hemoglobinuria
**myeloproliferative disorder
**Antiphospholipid antibody syndrome
**Essential thrombocytosis
**Inherited thrombotic diathesis
 
*Coagulopathies include the following:
**Protein C deficiency
**Protein S deficiency
**Antithrombin III deficiency
**Factor V Leiden deficiency
*Chronic infections like:
**Hydatid cysts
**Aspergillosis
**Amebic abscess
**Syphilis
**Tuberculosis
*Chronic inflammatory diseases such as:
**Behçet disease
**Inflammatory bowel disease
**Sarcoidosis
**Systemic lupus erythematosus
**Sjögren syndrome
**Mixed connective-tissue disease
*Tumors such as
**Hepatocellular carcinoma (HCC)
**Renal cell carcinoma
**Leiomyosarcoma
**Adrenal carcinoma
**Wilms tumor
**Right atrial myxoma
*Congenital membranous obstructions that includes the following:
**Type I: Thin membrane is present in the vena cava or the atrium
**Type II: A part of the vena cava is absent
**Type III: The inferior vena cava (IVC) cannot be filled, and collaterals have developed
*Miscellaneous risk factors of Budd-Chiari syndrome include the following:
**Alpha1-antitrypsin deficiency
**Dacarbazine
**Urethane
**Hypoplasia of the suprahepatic veins
**Postsurgical obstruction
**Posttraumatic obstruction
**Total parenteral nutrition (TPN): Budd-Chiari syndrome can be a complication of TPN via an IVC catheter in a neonate


==References==
==References==

Revision as of 10:22, 6 November 2017

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Risk Factors

  • Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder.Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome.

Associated risk factors include:

  • Hematologic disorders including:
    • Polycythemia rubra vera
    • Paroxysmal nocturnal hemoglobinuria
    • myeloproliferative disorder
    • Antiphospholipid antibody syndrome
    • Essential thrombocytosis
    • Inherited thrombotic diathesis
  • Coagulopathies include the following:
    • Protein C deficiency
    • Protein S deficiency
    • Antithrombin III deficiency
    • Factor V Leiden deficiency
  • Chronic infections like:
    • Hydatid cysts
    • Aspergillosis
    • Amebic abscess
    • Syphilis
    • Tuberculosis
  • Chronic inflammatory diseases such as:
    • Behçet disease
    • Inflammatory bowel disease
    • Sarcoidosis
    • Systemic lupus erythematosus
    • Sjögren syndrome
    • Mixed connective-tissue disease
  • Tumors such as
    • Hepatocellular carcinoma (HCC)
    • Renal cell carcinoma
    • Leiomyosarcoma
    • Adrenal carcinoma
    • Wilms tumor
    • Right atrial myxoma
  • Congenital membranous obstructions that includes the following:
    • Type I: Thin membrane is present in the vena cava or the atrium
    • Type II: A part of the vena cava is absent
    • Type III: The inferior vena cava (IVC) cannot be filled, and collaterals have developed
  • Miscellaneous risk factors of Budd-Chiari syndrome include the following:
    • Alpha1-antitrypsin deficiency
    • Dacarbazine
    • Urethane
    • Hypoplasia of the suprahepatic veins
    • Postsurgical obstruction
    • Posttraumatic obstruction
    • Total parenteral nutrition (TPN): Budd-Chiari syndrome can be a complication of TPN via an IVC catheter in a neonate

References

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