Whipple's disease laboratory findings: Difference between revisions
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{{Whipple's disease}} | {{Whipple's disease}} | ||
{{CMG}}; {{AE}} {{BHA}} | {{CMG}}; {{AE}} {{BHA}} | ||
==Overview== | ==Overview== | ||
Some patients with Whipple's disease may have abnormal hematological findings and elevated acute phase reactants, which is usually suggestive of the infection. Biopsy of the affected tissue is important to confirm the diagnosis. | |||
Some patients with | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
*An elevated level of [[acute phase reactants]] is seen in | *An elevated level of [[acute phase reactants]] is seen in Whipples disease. <ref name="pmid17202456">{{cite journal| author=Fenollar F, Puéchal X, Raoult D| title=Whipple's disease. | journal=N Engl J Med | year= 2007 | volume= 356 | issue= 1 | pages= 55-66 | pmid=17202456 | doi=10.1056/NEJMra062477 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17202456 }} </ref> | ||
*Hematological findings include: | *Hematological findings include:<ref name="pmid17202456">{{cite journal| author=Fenollar F, Puéchal X, Raoult D| title=Whipple's disease. | journal=N Engl J Med | year= 2007 | volume= 356 | issue= 1 | pages= 55-66 | pmid=17202456 | doi=10.1056/NEJMra062477 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17202456 }} </ref> | ||
**[[ | **[[Anemia]] | ||
**[[ | **[[Leukocytosis]] | ||
**[[ | **[[Thrombocytosis]]/[[Thrombocytopenia]] | ||
*Laboratory evidence of [[malabsorption]] may be seen.<ref name="pmid17202456">{{cite journal| author=Fenollar F, Puéchal X, Raoult D| title=Whipple's disease. | journal=N Engl J Med | year= 2007 | volume= 356 | issue= 1 | pages= 55-66 | pmid=17202456 | doi=10.1056/NEJMra062477 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17202456 }} </ref> | |||
*Laboratory evidence of [[malabsorption]] may be seen. <ref name="pmid17202456">{{cite journal| author=Fenollar F, Puéchal X, Raoult D| title=Whipple's disease. | journal=N Engl J Med | year= 2007 | volume= 356 | issue= 1 | pages= 55-66 | pmid=17202456 | doi=10.1056/NEJMra062477 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17202456 }} </ref> | |||
==References== | ==References== | ||
Revision as of 18:47, 7 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Bhagyashree Deshmankar M.B.B.S.[2]
Overview
Some patients with Whipple's disease may have abnormal hematological findings and elevated acute phase reactants, which is usually suggestive of the infection. Biopsy of the affected tissue is important to confirm the diagnosis.
Laboratory Findings
- An elevated level of acute phase reactants is seen in Whipples disease. [1]
- Hematological findings include:[1]
- Laboratory evidence of malabsorption may be seen.[1]
References
- ↑ 1.0 1.1 1.2 Fenollar F, Puéchal X, Raoult D (2007). "Whipple's disease". N Engl J Med. 356 (1): 55–66. doi:10.1056/NEJMra062477. PMID 17202456.