Whipple's disease laboratory findings: Difference between revisions
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Some patients with Whipple's disease may have abnormal [[hematological]] findings and elevated [[Acute phase reactant|acute phase reactants]], which is suggestive of the infection. [[Biopsy]] of the affected [[Tissue (biology)|tissue]] is important to confirm the diagnosis. | Some patients with Whipple's disease may have abnormal [[hematological]] findings and elevated [[Acute phase reactant|acute phase reactants]], which is suggestive of the infection. [[Biopsy]] of the affected [[Tissue (biology)|tissue]] is important to confirm the diagnosis. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Elevated level of [[acute phase reactants]] | *Elevated level of [[acute phase reactants]] | ||
*Hematological findings include: | **Elevated [[erythrocyte sedimentation rate]] ([[ESR]]) | ||
**[[Anemia]] | **Elevated [[C-reactive protein]] ([[CRP]]) | ||
*Hematological findings include: | |||
**[[Anemia]] due to [[intestinal]] [[blood loss]], [[iron deficiency]], and [[vitamin B12]] and [[Folic Acid|folic acid]] [[malabsorption]] | |||
**[[Leukocytosis]] | **[[Leukocytosis]] | ||
**[[Thrombocytosis]]/[[Thrombocytopenia]] | **[[Thrombocytosis]]/[[Thrombocytopenia]] | ||
*Laboratory evidence of [[malabsorption]] may be seen | *Laboratory evidence of [[malabsorption]] may be seen: | ||
** | **[[Hypoalbuminemia]] | ||
**[[Hypokalemia]] | |||
**[[Hypocalcemia]] | |||
**[[Hypomagnesemia]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:48, 13 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Bhagyashree Deshmankar M.B.B.S.[2]; Sadaf Sharfaei M.D.[3]
Overview
Some patients with Whipple's disease may have abnormal hematological findings and elevated acute phase reactants, which is suggestive of the infection. Biopsy of the affected tissue is important to confirm the diagnosis.
Laboratory Findings
- Elevated level of acute phase reactants
- Elevated erythrocyte sedimentation rate (ESR)
- Elevated C-reactive protein (CRP)
- Hematological findings include:
- Laboratory evidence of malabsorption may be seen: