21-hydroxylase deficiency surgery: Difference between revisions
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{{CMG}} {{AE}} {{MJ}} | {{CMG}} {{AE}} {{MJ}} | ||
== Overview == | == Overview == | ||
Reconstructive [[surgery]] and surgical [[adrenalectomy]]. | Reconstructive [[surgery]] and surgical [[adrenalectomy]]. Reconstructive [[Gynaecology|gynecologic]] [[surgery]] in [[Adolescent|adolescents]] or [[Adult|adults]], including clitoroplasty and [[vaginoplasty]]. Surgical adrenalectomy can be done in some cases, if there is no response to medical therapy. | ||
== Surgery == | == Surgery == | ||
=== '''Reconstructive surgery''' === | === '''Reconstructive surgery''' === | ||
* Reconstructive [[Gynaecology|gynecologic]] [[surgery]] in [[Adolescent|adolescents]] or [[Adult|adults]], including clitoroplasty and [[vaginoplasty]]<ref name="pmid9156043">{{cite journal| author=Premawardhana LD, Hughes IA, Read GF, Scanlon MF| title=Longer term outcome in females with congenital adrenal hyperplasia (CAH): the Cardiff experience. | journal=Clin Endocrinol (Oxf) | year= 1997 | volume= 46 | issue= 3 | pages= 327-32 | pmid=9156043 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9156043 }}</ref> | * Reconstructive [[Gynaecology|gynecologic]] [[surgery]] in [[Adolescent|adolescents]] or [[Adult|adults]], including clitoroplasty and [[vaginoplasty]]. <ref name="pmid9156043">{{cite journal| author=Premawardhana LD, Hughes IA, Read GF, Scanlon MF| title=Longer term outcome in females with congenital adrenal hyperplasia (CAH): the Cardiff experience. | journal=Clin Endocrinol (Oxf) | year= 1997 | volume= 46 | issue= 3 | pages= 327-32 | pmid=9156043 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9156043 }}</ref> | ||
=== '''Surgical adrenalectomy''' === | |||
* The major benefit is lowering [[Adrenal gland|adrenal]] [[androgen]] and [[progesterone]] secretion. However, it increases dependency on [[glucocorticoid]] and [[mineralocorticoid]] replacement therapy<ref name="pmid22904181">{{cite journal| author=Crocker MK, Barak S, Millo CM, Beall SA, Niyyati M, Chang R et al.| title=Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia. | journal=J Clin Endocrinol Metab | year= 2012 | volume= 97 | issue= 11 | pages= E2084-9 | pmid=22904181 | doi=10.1210/jc.2012-2298 | pmc=3485588 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22904181 }}</ref> | * Surgical adrenalectomy can be done in some cases, if there is no response to medical therapy. | ||
* The major benefit is lowering [[Adrenal gland|adrenal]] [[androgen]] and [[progesterone]] secretion. However, it increases dependency on [[glucocorticoid]] and [[mineralocorticoid]] replacement therapy. <ref name="pmid22904181">{{cite journal| author=Crocker MK, Barak S, Millo CM, Beall SA, Niyyati M, Chang R et al.| title=Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia. | journal=J Clin Endocrinol Metab | year= 2012 | volume= 97 | issue= 11 | pages= E2084-9 | pmid=22904181 | doi=10.1210/jc.2012-2298 | pmc=3485588 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22904181 }}</ref> | |||
== References == | == References == | ||
Revision as of 14:42, 14 November 2017
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21-hydroxylase deficiency Microchapters |
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Differentiating 21-Hydroxylase Deficiency from other Diseases |
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21-hydroxylase deficiency surgery On the Web |
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American Roentgen Ray Society Images of 21-hydroxylase deficiency surgery |
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Risk calculators and risk factors for 21-hydroxylase deficiency surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]
Overview
Reconstructive surgery and surgical adrenalectomy. Reconstructive gynecologic surgery in adolescents or adults, including clitoroplasty and vaginoplasty. Surgical adrenalectomy can be done in some cases, if there is no response to medical therapy.
Surgery
Reconstructive surgery
- Reconstructive gynecologic surgery in adolescents or adults, including clitoroplasty and vaginoplasty. [1]
Surgical adrenalectomy
- Surgical adrenalectomy can be done in some cases, if there is no response to medical therapy.
- The major benefit is lowering adrenal androgen and progesterone secretion. However, it increases dependency on glucocorticoid and mineralocorticoid replacement therapy. [2]
References
- ↑ Premawardhana LD, Hughes IA, Read GF, Scanlon MF (1997). "Longer term outcome in females with congenital adrenal hyperplasia (CAH): the Cardiff experience". Clin Endocrinol (Oxf). 46 (3): 327–32. PMID 9156043.
- ↑ Crocker MK, Barak S, Millo CM, Beall SA, Niyyati M, Chang R; et al. (2012). "Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia". J Clin Endocrinol Metab. 97 (11): E2084–9. doi:10.1210/jc.2012-2298. PMC 3485588. PMID 22904181.