Peptic ulcer risk factors: Difference between revisions

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Revision as of 20:02, 14 November 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ;Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overviews

Common risk factors in the development of peptic ulcer disease include chronic use of NSAIDs, cigarette smoking, alcohol intake, family history of peptic ulcer, and age >50 years.

Risk Factors

The most potent risk factor in the development of peptic ulcer disease is an infection from Helicobacter pylori. Other risk factors include chronic use of NSAIDs, tobacco smoking, and family history of peptic ulcer.

Common Risk Factors

Common risk factors in the development of peptic ulcer disease may be an infection, environmental, genetic, and lifestyle.
Common risk factors in the development of [disease name] include:
- Helicobacter pylori infection
- Chronic use of NSAIDs

Less Common Risk Factors

Less common risk factors in the development of peptic ulcer diease include:
- Tobacco
- Stress
- Anemia

References

Template:WikiDoc Sources

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 ==Risk Factors==
-Despite the finding that a [[bacterial infection]] is the cause of ulcers in 80% of cases, [[bacterial infection]] does not appear to explain all ulcers and researchers continue to look at stress as a possible cause, or at least a complication in the development of ulcers.
-An expert panel convened by the Academy of Behavioral Medicine research concluded that ulcers are not purely an [[infectious disease]] and that psychological factors do play a significant role. Researchers are examining how stress might promote ''H. pylori'' infection.  For example, ''Helicobacter pylori'' thrives in an acidic environment, and stress has been demonstrated to cause the production of excess stomach acid.
-The discovery that ''Helicobacter pylori'' is a cause of peptic ulcer has tempted many to conclude that psychological factors are unimportant. But this is dichotomised thinking. There is solid evidence that psychological stress triggers many ulcers and impairs response to treatment, while helicobacter is inadequate as a monocausal explanation as most infected people do not develop ulcers. Psychological stress probably functions most often as a cofactor with ''H pylori''. It may act by stimulating the production of [[gastric acid]] or by promoting behavior that causes a risk to health. Unravelling the aetiology of peptic ulcer will make an important contribution to the biopsychosocial model of disease.<ref name="bmj">{{cite web | url= http://bmj.bmjjournals.com/cgi/content/full/316/7130/538| title=Stress and peptic ulcer: life beyond helicobacter|accessdate=2007-08-26}}</ref>
-A study of peptic ulcer patients in a Thai hospital showed that chronic stress was strongly associated with an increased risk of peptic ulcer, and a combination of chronic stress and irregular mealtimes was a significant risk factor (PMID 12948263).
-A study on mice showed that both long-term water-immersion-restraint stress and ''H. pylori'' infection were independently associated with the development of peptic ulcers (PMID 12465722).
-The following factor raises the risk of peptic ulcer:
-* Episode of [[H. pylori]] infection.
-* Chronic use [[NSAID]]s.
-* [[Cigarette]]s/[[Alcohol]] intake.
-* Family history of peptic ulcer.
-* Age 50 years or more.
-There are no established risk factors for [disease name].
-OR
-The most potent risk factor in the development of [disease name] is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].
-OR
-Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
-OR
-Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.
 ==Risk Factors==

Peptic ulcer risk factors: Difference between revisions

Revision as of 20:02, 14 November 2017

Overviews

Risk Factors

Risk Factors

Common Risk Factors

Less Common Risk Factors

References

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