Pancreatic cancer differential diagnosis: Difference between revisions

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Revision as of 13:37, 15 November 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

The following diseases have a similar presentation as pancreatic cancer:

Origin	Disease	Differentiation based on Investigations
Pancreas	Chronic pancreatitis Autoimmune pancreatitis Pseudocyst of pancreas Neuroendocrine tumors of pancreas Gastrinoma VIPoma Somatostatinoma Insulinoma	Imaging: Non-contrast helical CT Biopsy findings Serum IgG4 levels for autoimmune pancreatitis For pancreatic NETs: Gastrin levels Somatostatin levels Insulin levels Serum electrolytes
Bile duct	Choledocholithiasis Gallstones (Cholelithiasis) Choledochal Cysts Cholangiocarcinoma Bile duct strictures Cholangitis Cholecystitis	Imaging: MRI MRCP USG bile duct ERCP Biopsy findings
Duodenum	Ampullary cancer Duodenal cancer	Imaging: MRI ERCP Upper GI Endoscopy Biopsy findings
Lymphovascular tissue	Abdominal aortic aneurysm Intestinal ischemia Lymphomas Gastric Pancreatic	Imaging: MRI MR Angiography CT Angiography Biopsy for lymphoma
Metastasis	Skin(Melanoma) Kidney Breast Colon Liver(Hepatocellular carcinoma) Stomach	Imaging: MRI PET scan CT Biopsy Specific markers for different cancers: HCC: AFP Breast: BRCA 1 and 2 Colon cancer: CEA Melanoma: S100

@@ Line 13: / Line 13: @@
 ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Differentiation based on Investigations
 |-
-| style="background:#DCDCDC; + " | Pancreas
+| style="background:#DCDCDC; + " | '''Pancreas'''
 |
 * Chronic pancreatitis
@@ Line 33: / Line 33: @@
 ** Serum electrolytes
 |-
-| style="background:#DCDCDC; + " | Bile duct
+| style="background:#DCDCDC; + " | '''Bile duct'''
 |
 * Choledocholithiasis
@@ Line 50: / Line 50: @@
 * Biopsy findings
 |-
-| style="background:#DCDCDC; + " | Duodenum
+| style="background:#DCDCDC; + " | '''Duodenum'''
 |
 * Ampullary cancer
@@ Line 61: / Line 61: @@
 * Biopsy findings
 |-
-| style="background:#DCDCDC; + " | Lymphovascular
+| style="background:#DCDCDC; + " | '''Lymphovascular
-tissue
+tissue'''
 |
 * Abdominal aortic aneurysm
@@ Line 76: / Line 76: @@
 * Biopsy for lymphoma
 |-
-| style="background:#DCDCDC; + " | Metastasis
+| style="background:#DCDCDC; + " | '''Metastasis'''
 |
 * Skin(Melanoma)