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==Screening== | ==Screening== | ||
*According to the Endocrine Society and the European Society for Pediatric Endocrinology, screening for congenital hypothyroidism (cretinism) is recommended in all [[neonates]]. Screening is recommended because early detection of cretinism and early treatment will prevent the consequences of the disease which may be [[mental retardation]].<ref name="pmid24446653">{{cite journal| author=Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G et al.| title=European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 2 | pages= 363-84 | pmid=24446653 | doi=10.1210/jc.2013-1891 | pmc=4207909 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24446653 }}</ref> | *According to the Endocrine Society and the European Society for Pediatric Endocrinology, screening for [[Cretinism|congenital hypothyroidism]] ([[cretinism]]) is recommended in all [[neonates]]. Screening is recommended because early detection of [[cretinism]] and early treatment will prevent the consequences of the disease which may be [[mental retardation]].<ref name="pmid24446653">{{cite journal| author=Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G et al.| title=European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 2 | pages= 363-84 | pmid=24446653 | doi=10.1210/jc.2013-1891 | pmc=4207909 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24446653 }}</ref> | ||
*In a worldwide view of strategies, screening of cretinism is been held in many countries including the United States. The screening helped in detecting the newborn with [[hypothyroidism]]. These cases are around 2000 annually in the united states and 12,000 worldwide.<ref name="pmid24629860">{{cite journal| author=Ford G, LaFranchi SH| title=Screening for congenital hypothyroidism: a worldwide view of strategies. | journal=Best Pract Res Clin Endocrinol Metab | year= 2014 | volume= 28 | issue= 2 | pages= 175-87 | pmid=24629860 | doi=10.1016/j.beem.2013.05.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24629860 }}</ref> | *In a worldwide view of strategies, screening of [[cretinism]] is been held in many countries including the United States. The screening helped in detecting the newborn with [[hypothyroidism]]. These cases are around 2000 annually in the united states and 12,000 worldwide.<ref name="pmid24629860">{{cite journal| author=Ford G, LaFranchi SH| title=Screening for congenital hypothyroidism: a worldwide view of strategies. | journal=Best Pract Res Clin Endocrinol Metab | year= 2014 | volume= 28 | issue= 2 | pages= 175-87 | pmid=24629860 | doi=10.1016/j.beem.2013.05.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24629860 }}</ref> | ||
*The screening of cretinism can be performed through the following laboratory tests:<ref name="pmid8533594">{{cite journal| author=Asami T, Otabe N, Wakabayashi M, Kikuchi T, Uchiyama M| title=Congenital hypothyroidism with delayed rise in serum TSH missed on newborn screening. | journal=Acta Paediatr Jpn | year= 1995 | volume= 37 | issue= 5 | pages= 634-7 | pmid=8533594 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8533594 }}</ref><ref name="pmid23154158">{{cite journal| author=Büyükgebiz A| title=Newborn screening for congenital hypothyroidism. | journal=J Clin Res Pediatr Endocrinol | year= 2013 | volume= 5 Suppl 1 | issue= | pages= 8-12 | pmid=23154158 | doi=10.4274/jcrpe.845 | pmc=3608007 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23154158 }}</ref> | *The screening of [[cretinism]] can be performed through the following laboratory tests:<ref name="pmid8533594">{{cite journal| author=Asami T, Otabe N, Wakabayashi M, Kikuchi T, Uchiyama M| title=Congenital hypothyroidism with delayed rise in serum TSH missed on newborn screening. | journal=Acta Paediatr Jpn | year= 1995 | volume= 37 | issue= 5 | pages= 634-7 | pmid=8533594 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8533594 }}</ref><ref name="pmid23154158">{{cite journal| author=Büyükgebiz A| title=Newborn screening for congenital hypothyroidism. | journal=J Clin Res Pediatr Endocrinol | year= 2013 | volume= 5 Suppl 1 | issue= | pages= 8-12 | pmid=23154158 | doi=10.4274/jcrpe.845 | pmc=3608007 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23154158 }}</ref> | ||
**Measuring the level of [[Thyroxine|thyroxine hormone]] (T4) | **Measuring the level of [[Thyroxine|thyroxine hormone]] (T4) | ||
**[[Blood]] [[TSH]] assay | **[[Blood]] [[TSH]] assay | ||
**Both [[thyroxine]] and [[TSH]] levels | **Both [[thyroxine]] and [[TSH]] levels | ||
<references /> | |||
Revision as of 22:05, 20 November 2017
Screening
- According to the Endocrine Society and the European Society for Pediatric Endocrinology, screening for congenital hypothyroidism (cretinism) is recommended in all neonates. Screening is recommended because early detection of cretinism and early treatment will prevent the consequences of the disease which may be mental retardation.[1]
- In a worldwide view of strategies, screening of cretinism is been held in many countries including the United States. The screening helped in detecting the newborn with hypothyroidism. These cases are around 2000 annually in the united states and 12,000 worldwide.[2]
- The screening of cretinism can be performed through the following laboratory tests:[3][4]
- Measuring the level of thyroxine hormone (T4)
- Blood TSH assay
- Both thyroxine and TSH levels
- ↑ Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G; et al. (2014). "European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism". J Clin Endocrinol Metab. 99 (2): 363–84. doi:10.1210/jc.2013-1891. PMC 4207909. PMID 24446653.
- ↑ Ford G, LaFranchi SH (2014). "Screening for congenital hypothyroidism: a worldwide view of strategies". Best Pract Res Clin Endocrinol Metab. 28 (2): 175–87. doi:10.1016/j.beem.2013.05.008. PMID 24629860.
- ↑ Asami T, Otabe N, Wakabayashi M, Kikuchi T, Uchiyama M (1995). "Congenital hypothyroidism with delayed rise in serum TSH missed on newborn screening". Acta Paediatr Jpn. 37 (5): 634–7. PMID 8533594.
- ↑ Büyükgebiz A (2013). "Newborn screening for congenital hypothyroidism". J Clin Res Pediatr Endocrinol. 5 Suppl 1: 8–12. doi:10.4274/jcrpe.845. PMC 3608007. PMID 23154158.