Ewing's sarcoma biopsy

Ewing's sarcoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

Biopsy of Ewing's sarcoma is important for confirming the diagnosis and determining histologic subtype. Biopsy may be performed percutaneously with either a fine-needle or wide-bore needle, or through a formal incision.

Biopsy

• Biopsy of Ewing's sarcoma is important for confirming the diagnosis and the determining histologic subtype.
• Biopsy may be performed percutaneously with either a fine-needle, or a wide-bore needle, or through a formal incision.
• More invasive methods carry a higher risk of complications and contamination of tissue planes. Each year 30% of patients lose their limbs through inappropriate biopsy site and technique. In principle, biopsies should be performed at a tumor center by a specialist in tumor surgery.
• Inappropriate alignment of the biopsy or inadvertent contamination of soft tissues can render subsequent limb-preserving reconstructive surgery impossible.

To view histopathologic characteristic features of Ewing's sarcoma, click here.