Tumor lysis syndrome laboratory findings

Tumor lysis syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Tumor lysis syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Tumor lysis syndrome laboratory findings On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Tumor lysis syndrome laboratory findings All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Tumor lysis syndrome laboratory findings
CDC on Tumor lysis syndrome laboratory findings
Tumor lysis syndrome laboratory findings in the news
Blogs on Tumor lysis syndrome laboratory findings
Directions to Hospitals Treating Tumor lysis syndrome
Risk calculators and risk factors for Tumor lysis syndrome laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Laboratory findings consistent with the diagnosis of tumor lysis syndrome include high serum uric acid, potassium, phosphorus, and low calcium.

Laboratory Findings

Laboratory findings consistent with the diagnosis of tumor lysis syndrome include:

• Blood:

• Hyperuricemia ≥ 476 μmol/l
• Hyperphosphatemia ≥ 2·1 mmol/l (children), x ≥1·45 mmol/l (adults)
• Hyperkalemia ≥ 6·0 mmol/l
• Hypocalcemia ≤ 1·75 mmol/l
• Creatinine ≥1.5 x ULN
• Metabolica acidosis

• Urinalysis:

• Low urine output
• Uric acid crystals or amorphous urates
• High uric acid-creatinine ratio > 1.0