Portal vein thrombosis causes

Portal vein thrombosis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Disease name] may be caused by [cause1], [cause2], or [cause3].

OR

Common causes of [disease] include [cause1], [cause2], and [cause3].

OR

The most common cause of [disease name] is [cause 1]. Less common causes of [disease name] include [cause 2], [cause 3], and [cause 4].

OR

The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click here.

Causes

Life-threatening Causes

• Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of disease name, however complications resulting from untreated disease name is common.
• Life-threatening causes of [symptom/manifestation] include [cause1], [cause2], and [cause3].
• [Cause] is a life-threatening cause of [disease].

Common Causes

Portal vein thrombosis may be caused by:

• Inherited prothrombotic disorders
  • Factor V Leiden mutation
  • Factor II gene mutation
  • Protein C deficiency
  • Protein S deficiency
  • Antithrombin III deficiency
• Acquired thrombophilic disorders
  • Primary myeloproliferative disorders
  • Paroxysmal nocturnal hemoglobinemia
  • Antiphospholipid syndrome
  • Increased factor VIII levels
  • Thrombin activatable fibrinolysis inhibitor gene (TAFI)
• Procedures
  • Abdominal surgery or surgical injury of the portal vein axis
  • Endoscopic sclerotherapy
  • Transjugular intrahepatic portosystemic shunt
  • Splenectomy
  • Hepatic resection
  • Pancreatic islet cell transplantation
• Acquired conditions
  • Cirrhosis
  • Hepatocellular carcinoma
  • Philadelphia-chromosome negative chronic myeloproliferative disorders (polycythemia vera, essential thrombocythemia, idiopathic myelofibrosis, unclassifiable myeloproliferative disorders) (see "Overview of the myeloproliferative neoplasms")
  • Antiphospholipid syndrome
  • Paroxysmal nocturnal hemoglobinuria
  • Behçet's syndrome
  • Recent pregnancy or oral contraceptive use
  • Abdominal inflammatory lesions including infection, pancreatitis, and inflammatory bowel disease
  • Trauma

Less Common Causes

Less common causes of disease name include:

• [Cause1]
• [Cause2]
• [Cause3]

Genetic Causes

• [Disease name] is caused by a mutation in the [gene name] gene.

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	No underlying causes
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

List the causes of the disease in alphabetical order.

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