Spontaneous coronary artery dissection causes: Difference between revisions
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==Causes== | ==Causes== | ||
The exact etiology of spontaneous coronary artery dissection (SCAD) remains elusive and appears to be multifactorial. It has been postulated that the phenotypic manifestation of SCAD may occur as a result of predisposing factors compounded by precipitating stressors.<ref name="SawMancini2016">{{cite journal|last1=Saw|first1=Jacqueline|last2=Mancini|first2=G.B. John|last3=Humphries|first3=Karin H.|title=Contemporary Review on Spontaneous Coronary Artery Dissection|journal=Journal of the American College of Cardiology|volume=68|issue=3|year=2016|pages=297–312|issn=07351097|doi=10.1016/j.jacc.2016.05.034}}</ref> Conditions that have been implicated as a potential cause include: | The exact etiology of spontaneous coronary artery dissection (SCAD) remains elusive and appears to be multifactorial. It has been postulated that the phenotypic manifestation of SCAD may occur as a result of predisposing factors compounded by precipitating stressors.<ref name="SawMancini2016">{{cite journal|last1=Saw|first1=Jacqueline|last2=Mancini|first2=G.B. John|last3=Humphries|first3=Karin H.|title=Contemporary Review on Spontaneous Coronary Artery Dissection|journal=Journal of the American College of Cardiology|volume=68|issue=3|year=2016|pages=297–312|issn=07351097|doi=10.1016/j.jacc.2016.05.034}}</ref> Conditions that have been implicated as a potential cause include: | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Predisposing factors''' | | style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Predisposing factors''' | ||
| style="background: #F5F5F5; padding: 5px;" colspan="2;"| | | style="background: #F5F5F5; padding: 5px;" colspan="2;"| | ||
* Fibromuscular dysplasia | * [[Fibromuscular dysplasia]] | ||
* Takotsubo cardiomyopathy | * [[Takotsubo cardiomyopathy]] | ||
* Pregnancy-related: antepartum, early post-partum, late post-partum, very late post-partum | * [[Pregnancy]]-related: antepartum, early post-partum, late post-partum, very late post-partum | ||
* Recurrent pregnancies: multiparity or multigravida | * Recurrent pregnancies: [[Parity (medicine)|multiparity]] or [[multigravida]] | ||
* Connective tissue disorder: Marfan syndrome, Loeys-Dietz syndrome, Ehlers-Danlos syndrome type 4, cystic medial necrosis, alpha-1 antitrypsin deficiency, polycystic kidney disease | * [[Connective tissue disorder]]: [[Marfan syndrome]], [[Loeys-Dietz syndrome]], [[Ehlers-Danlos syndrome|Ehlers-Danlos syndrome type 4]], [[cystic medial necrosis]], [[alpha-1 antitrypsin deficiency]], [[polycystic kidney disease]] | ||
* Systemic inflammatory disease: systemic lupus erythematosus, Crohn's disease, ulcerative colitis, polyarteritis nodosa, sarcoidosis, Churg-Strauss syndrome, Wegener's granulomatosis, rheumatoid arthritis, Kawasaki disease, giant cell arteritis, celiac disease | * [[Systemic inflammation|Systemic inflammatory disease]]: [[systemic lupus erythematosus]], [[Crohn's disease]], [[ulcerative colitis]], [[polyarteritis nodosa]], [[sarcoidosis]], [[Churg-Strauss syndrome]], [[Wegener's granulomatosis]], [[rheumatoid arthritis]], [[Kawasaki disease]], [[giant cell arteritis]], [[celiac disease]] | ||
* Hormonal therapy: oral contraceptive, estrogen, progesterone, beta-HCG, testosterone, corticosteroids | * Hormonal therapy: [[oral contraceptive]], [[estrogen]], [[progesterone]], [[beta-HCG]], [[testosterone]], [[corticosteroids]] | ||
* Coronary artery spasm | * [[Coronary artery spasm]] | ||
* Idiopathic | * [[Idiopathic]] | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Precipitating stressors''' | | style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Precipitating stressors''' |
Revision as of 19:40, 28 November 2017
Spontaneous Coronary Artery Dissection Microchapters |
Differentiating Spontaneous coronary artery dissection from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Type 1 Type 2A Type 2B Type 3 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.
Synonyms and keywords: SCAD
Overview
Spontaneous coronary artery dissection may occur as a result of predisposing factors (e.g., vasculopathy, connective tissue disorder, systemic inflammation) compounded by precipitating stressors (strenuous exercise, emotional stress, medications).
Causes
The exact etiology of spontaneous coronary artery dissection (SCAD) remains elusive and appears to be multifactorial. It has been postulated that the phenotypic manifestation of SCAD may occur as a result of predisposing factors compounded by precipitating stressors.[1] Conditions that have been implicated as a potential cause include:
References
- ↑ Saw, Jacqueline; Mancini, G.B. John; Humphries, Karin H. (2016). "Contemporary Review on Spontaneous Coronary Artery Dissection". Journal of the American College of Cardiology. 68 (3): 297–312. doi:10.1016/j.jacc.2016.05.034. ISSN 0735-1097.