Primary sclerosing cholangitis classification: Difference between revisions
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==Overview== | ==Overview== | ||
Primary sclerosing cholangitis may be classified according to the size of [[bile ducts]] involved, as well as its association with [[autoimmune hepatitis]]. The | Primary sclerosing cholangitis may be classified according to the size of [[bile ducts]] involved, as well as its association with [[autoimmune hepatitis]]. The three main subtypes are the classic subtype, small ducts subtype, and primary sclerosing cholangitis associated with [[autoimmune hepatitis]]. | ||
==Classification== | ==Classification== | ||
Primary sclerosing cholangitis may be divided into 3 subtypes, according to the type of ducts involved, as well as its association with [[autoimmune hepatitis]]:<ref name="pmid27653566">{{cite journal |vauthors=Lazaridis KN, LaRusso NF |title=Primary Sclerosing Cholangitis |journal=N. Engl. J. Med. |volume=375 |issue=12 |pages=1161–70 |year=2016 |pmid=27653566 |doi=10.1056/NEJMra1506330 |url=}}</ref><ref name="pmid12029635">{{cite journal |vauthors=Angulo P, Maor-Kendler Y, Lindor KD |title=Small-duct primary sclerosing cholangitis: a long-term follow-up study |journal=Hepatology |volume=35 |issue=6 |pages=1494–500 |year=2002 |pmid=12029635 |doi=10.1053/jhep.2002.33202 |url=}}</ref><ref name="pmid12830004">{{cite journal |vauthors=Feldstein AE, Perrault J, El-Youssif M, Lindor KD, Freese DK, Angulo P |title=Primary sclerosing cholangitis in children: a long-term follow-up study |journal=Hepatology |volume=38 |issue=1 |pages=210–7 |year=2003 |pmid=12830004 |doi=10.1053/jhep.2003.50289 |url=}}</ref><ref name="pmid11059857">{{cite journal |vauthors=Kaya M, Angulo P, Lindor KD |title=Overlap of autoimmune hepatitis and primary sclerosing cholangitis: an evaluation of a modified scoring system |journal=J. Hepatol. |volume=33 |issue=4 |pages=537–42 |year=2000 |pmid=11059857 |doi= |url=}}</ref> | Primary sclerosing cholangitis may be divided into 3 subtypes, according to the type of ducts involved, as well as its association with [[autoimmune hepatitis]]:<ref name="pmid27653566">{{cite journal |vauthors=Lazaridis KN, LaRusso NF |title=Primary Sclerosing Cholangitis |journal=N. Engl. J. Med. |volume=375 |issue=12 |pages=1161–70 |year=2016 |pmid=27653566 |doi=10.1056/NEJMra1506330 |url=}}</ref><ref name="pmid12029635">{{cite journal |vauthors=Angulo P, Maor-Kendler Y, Lindor KD |title=Small-duct primary sclerosing cholangitis: a long-term follow-up study |journal=Hepatology |volume=35 |issue=6 |pages=1494–500 |year=2002 |pmid=12029635 |doi=10.1053/jhep.2002.33202 |url=}}</ref><ref name="pmid12830004">{{cite journal |vauthors=Feldstein AE, Perrault J, El-Youssif M, Lindor KD, Freese DK, Angulo P |title=Primary sclerosing cholangitis in children: a long-term follow-up study |journal=Hepatology |volume=38 |issue=1 |pages=210–7 |year=2003 |pmid=12830004 |doi=10.1053/jhep.2003.50289 |url=}}</ref><ref name="pmid11059857">{{cite journal |vauthors=Kaya M, Angulo P, Lindor KD |title=Overlap of autoimmune hepatitis and primary sclerosing cholangitis: an evaluation of a modified scoring system |journal=J. Hepatol. |volume=33 |issue=4 |pages=537–42 |year=2000 |pmid=11059857 |doi= |url=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
!align="center" style="background: #4479BA; color: #FFFFFF; " |Subtype | ! align="center" style="background: #4479BA; color: #FFFFFF; " |Subtype | ||
!align="center" style="background: #4479BA; color: #FFFFFF; " |Ducts Involved | ! align="center" style="background: #4479BA; color: #FFFFFF; " |Ducts Involved | ||
!align="center" style="background: #4479BA; color: #FFFFFF; " |Diagnostic Procedure | ! align="center" style="background: #4479BA; color: #FFFFFF; " |Diagnostic Procedure | ||
!align="center" style="background: #4479BA; color: #FFFFFF; " |Histopathology | ! align="center" style="background: #4479BA; color: #FFFFFF; " |Histopathology | ||
|- | |- | ||
|Classic | |Classic | ||
Latest revision as of 17:35, 5 December 2017
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Primary sclerosing cholangitis Microchapters |
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Differentiating Primary sclerosing cholangitis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary sclerosing cholangitis classification On the Web |
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American Roentgen Ray Society Images of Primary sclerosing cholangitis classification |
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Directions to Hospitals Treating Primary sclerosing cholangitis |
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Risk calculators and risk factors for Primary sclerosing cholangitis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Primary sclerosing cholangitis may be classified according to the size of bile ducts involved, as well as its association with autoimmune hepatitis. The three main subtypes are the classic subtype, small ducts subtype, and primary sclerosing cholangitis associated with autoimmune hepatitis.
Classification
Primary sclerosing cholangitis may be divided into 3 subtypes, according to the type of ducts involved, as well as its association with autoimmune hepatitis:[1][2][3][4]
| Subtype | Ducts Involved | Diagnostic Procedure | Histopathology |
|---|---|---|---|
| Classic | Small and large bile ducts | MRCP, ERCP | Mixed inflammatory cells around bile ducts; nonspecific and nondiagnostic finding |
| Small duct | Small bile ducts only | Liver biopsy | Mixed inflammatory cells around bile ducts; nonspecific and nondiagnostic finding |
| Associated with autoimmune hepatitis | Small and large bile ducts | MRCP, ERCP | Lymphoplasmacytic infiltrate, associated with interface hepatitis |
References
- ↑ Lazaridis KN, LaRusso NF (2016). "Primary Sclerosing Cholangitis". N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Angulo P, Maor-Kendler Y, Lindor KD (2002). "Small-duct primary sclerosing cholangitis: a long-term follow-up study". Hepatology. 35 (6): 1494–500. doi:10.1053/jhep.2002.33202. PMID 12029635.
- ↑ Feldstein AE, Perrault J, El-Youssif M, Lindor KD, Freese DK, Angulo P (2003). "Primary sclerosing cholangitis in children: a long-term follow-up study". Hepatology. 38 (1): 210–7. doi:10.1053/jhep.2003.50289. PMID 12830004.
- ↑ Kaya M, Angulo P, Lindor KD (2000). "Overlap of autoimmune hepatitis and primary sclerosing cholangitis: an evaluation of a modified scoring system". J. Hepatol. 33 (4): 537–42. PMID 11059857.