Mesenteric ischemia natural history, complications and prognosis: Difference between revisions
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* [[Arterial embolism]] - 54% mortality | * [[Arterial embolism]] - 54% mortality | ||
* [[Arterial thrombosis]] - 77% mortality | * [[Arterial thrombosis]] - 77% mortality | ||
* [[Non-occlusive ischemia]] - | * [[Non-occlusive ischemia]] - 70-90% mortality<ref name="pmid28691670">{{cite journal| author=Salamone G, Raspanti C, Licari L, Falco N, Rotolo G, Augello G et al.| title=Non-Occlusive Mesenteric Ischemia (NOMI) in Parkinson's disease: case report. | journal=G Chir | year= 2017 | volume= 38 | issue= 2 | pages= 71-76 | pmid=28691670 | doi= | pmc=5509387 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28691670 }} </ref> | ||
==Complications== | ==Complications== | ||
Revision as of 22:11, 9 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Natural History
Three progressive phases of ischemic colitis have been described:[1][2]
- A hyperactive phase occurs first, in which the primary symptoms are severe abdominal pain and the passage of bloody stools. Many patients get better and do not progress beyond this phase.
- A paralytic phase can follow if ischemia continues; in this phase, the abdominal pain becomes more widespread, the belly becomes more tender to the touch, and bowel motility decreases, resulting in abdominal bloating, no further bloody stools, and absent bowel sounds on exam.
- Finally, a shock phase can develop as fluids start to leak through the damaged colon lining. This can result in shock and metabolic acidosis with dehydration, low blood pressure, rapid heart rate, and confusion. Patients who progress to this phase are often critically ill and require intensive care.
Prognosis
In the case of chronic mesenteric ischemia, the outlook after a successful surgery is good. However, if appropriate lifestyle changes (such as a healthy diet and exercise) are not made, any problems with artherosclerosis will generally get worse over time. Persons with acute mesenteric ischemia usually do poorly, since death of the intestine often occurs before surgery is done. However, when diagnosed and treated right away, patients with acute mesenteric ischemia can be treated successfully.The prognosis depends on prompt diagnosis (less than 12-24 hours and before gangrene)[3] and the the underlying cause[4]:
- Venous thrombosis - 32% mortality
- Arterial embolism - 54% mortality
- Arterial thrombosis - 77% mortality
- Non-occlusive ischemia - 70-90% mortality[5]
Complications
Tissue death from lack of blood flow (infarction) in the intestines is the most serious complication of mesenteric artery ischemia. Surgery may be needed to remove the dead portion.
References
- ↑ Boley, SJ, Brandt, LJ, Veith, FJ. Ischemic disorders of the intestines. Curr Probl Surg 1978; 15:1.
- ↑ Hunter G, Guernsey J (1988). "Mesenteric ischemia". Med Clin North Am. 72 (5): 1091–115. PMID 3045452.
- ↑ .
- ↑ Schoots IG, Koffeman GI, Legemate DA, Levi M, van Gulik TM (2004). "Systematic review of survival after acute mesenteric ischaemia according to disease aetiology". The British journal of surgery. 91 (1): 17–27. PMID 14716789.
- ↑ Salamone G, Raspanti C, Licari L, Falco N, Rotolo G, Augello G; et al. (2017). "Non-Occlusive Mesenteric Ischemia (NOMI) in Parkinson's disease: case report". G Chir. 38 (2): 71–76. PMC 5509387. PMID 28691670.