Sandbox: wdx causes

Short bowel syndrome is the result of bowel resection following various causes including Crohn's disease, malignancies, ischemia, and trauma. The small intestine less than 2 meters is considered as short bowel syndrome and requires nutritional therapy to prevent malnutrition. Post bowel resection adaptation might occur which includes structural, motility and functional changes in the remaining intestine. Changes usually start in the first 24 hours following bowel resection and last for about two years. Adaptation depends on multiple factors including individual, intestinal and therapeutic measurements. Following the bowel resection, adaptation occurs in three phases including acute, adaptive, and maintenance phases. Successful adaptation depends on the length of remaining intestine, portion of the resected intestine, and early introduction of nutrition therapy. Total intestinal adaptation defines as when patient is weaned from parenteral nutrition. The main reason for malabsorption following bowel resection isreduced absorption capacity of the small intestine due to loss of surface area. On gross and microscopic pathology, the resected bowel may show the underlying causes including Crohn's disease, malignancies or ischemia.