Lactose intolerance epidemiology and demographics: Difference between revisions
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* The prevalence of lactose intoleance are low in children younger than six years. <ref name="pmid8026265">{{cite journal |vauthors=Rao DR, Bello H, Warren AP, Brown GE |title=Prevalence of lactose maldigestion. Influence and interaction of age, race, and sex |journal=Dig. Dis. Sci. |volume=39 |issue=7 |pages=1519–24 |year=1994 |pmid=8026265 |doi= |url=}}</ref><ref name="pmid11761016">{{cite journal |vauthors=Di Stefano M, Veneto G, Malservisi S, Strocchi A, Corazza GR |title=Lactose malabsorption and intolerance in the elderly |journal=Scand. J. Gastroenterol. |volume=36 |issue=12 |pages=1274–8 |year=2001 |pmid=11761016 |doi= |url=}}</ref> | * The prevalence of lactose intoleance are low in children younger than six years. <ref name="pmid8026265">{{cite journal |vauthors=Rao DR, Bello H, Warren AP, Brown GE |title=Prevalence of lactose maldigestion. Influence and interaction of age, race, and sex |journal=Dig. Dis. Sci. |volume=39 |issue=7 |pages=1519–24 |year=1994 |pmid=8026265 |doi= |url=}}</ref><ref name="pmid11761016">{{cite journal |vauthors=Di Stefano M, Veneto G, Malservisi S, Strocchi A, Corazza GR |title=Lactose malabsorption and intolerance in the elderly |journal=Scand. J. Gastroenterol. |volume=36 |issue=12 |pages=1274–8 |year=2001 |pmid=11761016 |doi= |url=}}</ref> | ||
* The prevalence of lactose intoleance inceresed with age | * The prevalence of lactose intoleance inceresed with age. | ||
===Race=== | ===Race=== |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
The prevalence of lactose intolerance is approximately 75000 per 100,000 individuals worldwide. The prevalence of lactose intoleance are low in children younger than six years. Europeans and European Americans individuals are less likely to develop lactose intolerance. Lactose intolerance affects men and women equally. The majority of lactose intolerance cases are reported in Far East.
Epidemiology and Demographics
Prevalence
- The prevalence of lactose intolerance is approximately 75000 per 100,000 individuals worldwide.[1]
- In North America, the prevalence of lactose intolerance:
- Native America: 79000 per 100,000 individuals
- Black: 75000 per 100,000 individuals
- Hispanics: 51000 per 100,000 individuals
- Caucasians: 21000 per 100,000 individuals
- The prevalence of lactose intolerance in Latin America, Africa, and Asia is 15000-100000 per 100,000 individuals.
Age
- The prevalence of lactose intoleance are low in children younger than six years. [2][3]
- The prevalence of lactose intoleance inceresed with age.
Race
- Lactose intolerance usually affects individuals of the:[4][5]
- African Americans
- Hispanics
- Asians
- Asian Americans
- Native Americans
- Europeans and European Americans individuals are less likely to develop lactose intolerance.
Gender
- Lactose intolerance affects men and women equally.
Region
- The majority of lactose intolerance cases are reported in Far East.[6]
- Around the North Sea, in Northwestern Europe has the lowest prevalence of lactose intolerance.
- High rates of lactase intolerance in Africa:[7]
- Nigeria
- Malawi
- Sudan
- Ethiopia
- Uganda
- Low rates of lactose intolerance in Africa:
- Cameroon
- Mali
- South Africa
- Morocco
- Congenital lactase deficiency is a rare disease that tends to affect Finnish population.[8]
Developing Countries
- Secondary lactase deficiency is more common in children, particularly in developing countries due to high prevalence of infections. [9]
References
- ↑ Silanikove N, Leitner G, Merin U (2015). "The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds". Nutrients. 7 (9): 7312–31. doi:10.3390/nu7095340. PMC 4586535. PMID 26404364.
- ↑ Rao DR, Bello H, Warren AP, Brown GE (1994). "Prevalence of lactose maldigestion. Influence and interaction of age, race, and sex". Dig. Dis. Sci. 39 (7): 1519–24. PMID 8026265.
- ↑ Di Stefano M, Veneto G, Malservisi S, Strocchi A, Corazza GR (2001). "Lactose malabsorption and intolerance in the elderly". Scand. J. Gastroenterol. 36 (12): 1274–8. PMID 11761016.
- ↑ Scrimshaw NS, Murray EB (1988). "The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance". Am. J. Clin. Nutr. 48 (4 Suppl): 1079–159. PMID 3140651.
- ↑ Itan Y, Jones BL, Ingram CJ, Swallow DM, Thomas MG (2010). "A worldwide correlation of lactase persistence phenotype and genotypes". BMC Evol. Biol. 10: 36. doi:10.1186/1471-2148-10-36. PMC 2834688. PMID 20144208.
- ↑ Sahi T (1994). "Genetics and epidemiology of adult-type hypolactasia". Scand. J. Gastroenterol. Suppl. 202: 7–20. PMID 8042019.
- ↑ Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
- ↑ Järvelä I, Enattah NS, Kokkonen J, Varilo T, Savilahti E, Peltonen L (1998). "Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-phlorizin hydrolase gene". Am. J. Hum. Genet. 63 (4): 1078–85. PMC 1377496. PMID 9758622.
- ↑ Bhatnagar S, Aggarwal R (2007). "Lactose intolerance". BMJ. 334 (7608): 1331–2. doi:10.1136/bmj.39252.524375.80. PMC 1906652. PMID 17599979.