Barrett's esophagus future or investigational therapies: Difference between revisions

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==Overview==
==Overview==
* Biomarkers
* Biomarkers
# [[Can]] [[not]] [[be]] [[used]] [[to]] [[confirm]] [[the]] [[diagnosis]] [[of]] [[Barrett´s esophagus]].
# Can not be used to confirm the [[diagnosis]] of Barrett´s esophagus.
# [[Can]] [[not]] [[be]] [[used]] [[to]] [[predict]] [[risk]] [[of]] [[progression]].
# Can not be used to predict risk of progression.
# [[Promising]] [[for]] [[the]] [[future]]<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011 |month=March |pmid=21376940 |doi=10.1053/j.gastro.2011.01.030 |url=}}</ref>.
# Promising for the future<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011 |month=March |pmid=21376940 |doi=10.1053/j.gastro.2011.01.030 |url=}}</ref>.




* Endoscopic Therapy
* Endoscopic Therapy
# [[In]] [[patients]] [[with]] [[confirmed]] [[high-grade]] [[dysplasia]] [[with]] [[Barrett' esophagus]], [[it]] [[is]] [[more]] [[recommended]] [[to]] [[proceed]] [[with]] [[endoscopic]] [[eradication]] [[therapy]] [[with]] [[radiofrequency]] [[ablation]] ([[RFA]]), [[photodynamic]] [[therapy]] ([[PDT]]), [[or]] [[endoscopic]] [[mucosal]] [[resection]] ([[EMR]]) [[rather]] [[than]] [[surveillance]].
# In [[patients]] with confirmed high-grade [[dysplasia]] with Barrett' esophagus, it is more recommended to proceed with [[endoscopic]] eradication [[therapy]] with [[radiofrequency]] [[ablation]] ([[RFA]]), photodynamic [[therapy]] (PDT), or [[endoscopic]] [[mucosal]] [[resection]] (EMR) rather than surveillance.
# [[In]] [[patients]] [[who]] [[have]] [[dysplasia]] [[in]] [[Barrett's esophagus]] [[associated]] [[with]] [[a]] [[visible]] [[mucosal]] [[irregularity]] [[it]] [[is]] [[recommended]] [[to]] [[proceed]] [[with]] [[endoscopic]] [[mucosal]] [[resection]] ([[EMR]]) [[to]] [[determine]] [[the]] [[T stage]] [[of]] [[the]] [[neoplasia]]<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011 |month=March |pmid=21376940 |doi=10.1053/j.gastro.2011.01.030 |url=}}</ref>.
# In [[patients]] who have [[dysplasia]] in [[Barrett's esophagus]] associated with a visible [[mucosal]] irregularity it is recommended to proceed with [[endoscopic]] [[mucosal]] [[resection]] (EMR) to determine the T stage of the [[neoplasia]]<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011 |month=March |pmid=21376940 |doi=10.1053/j.gastro.2011.01.030 |url=}}</ref>.


==References==
==References==

Latest revision as of 21:50, 15 December 2017

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Overview

  • Biomarkers
  1. Can not be used to confirm the diagnosis of Barrett´s esophagus.
  2. Can not be used to predict risk of progression.
  3. Promising for the future[1].


  • Endoscopic Therapy
  1. In patients with confirmed high-grade dysplasia with Barrett' esophagus, it is more recommended to proceed with endoscopic eradication therapy with radiofrequency ablation (RFA), photodynamic therapy (PDT), or endoscopic mucosal resection (EMR) rather than surveillance.
  2. In patients who have dysplasia in Barrett's esophagus associated with a visible mucosal irregularity it is recommended to proceed with endoscopic mucosal resection (EMR) to determine the T stage of the neoplasia[1].

References

  1. ↑ 1.0 1.1 Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. doi:10.1053/j.gastro.2011.01.030. PMID 21376940. Unknown parameter |month= ignored (help)

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