Gastrointestinal stromal tumor other imaging findings: Difference between revisions
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*Smooth submucosal mass | *Smooth submucosal mass | ||
*Areas of [[ulceration]] or [[bleeding]] | *Areas of [[ulceration]] or [[bleeding]] | ||
[[Image:GIST 2.jpg|thumb|left|[[Endoscopy|Endoscopic]] image of GIST in the fundus of [[stomach]]. ([Courtesy: By Samir, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=1257100])]] | [[Image:GIST 2.jpg|thumb|left|[[Endoscopy|Endoscopic]] image of GIST in the fundus of [[stomach]]. ([Courtesy: By Samir, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=1257100])]] | ||
[[image:GIST 3.jpg|thumb|center|[[Endoscopy|Endoscopic]] image of GIST in the fundus of stomach with an overlying clot. ([Courtesy: By Samir (http://en.wikipedia.org/wiki/Image:GIST_3.jpg) [GFDL (http://www.gnu.org/copyleft/fdl.html) or CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0/)], via Wikimedia Commons])]] | [[image:GIST 3.jpg|thumb|center|[[Endoscopy|Endoscopic]] image of GIST in the fundus of stomach with an overlying clot. ([Courtesy: By Samir (http://en.wikipedia.org/wiki/Image:GIST_3.jpg) [GFDL (http://www.gnu.org/copyleft/fdl.html) or CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0/)], via Wikimedia Commons])]] | ||
Endoscopic guided biopsy may be done for definite diagnosis of gastrointestinal stromal tumor (GIST). However, percutaneous biopsy is not routinely recommended. | |||
*Patients with unresectable GIST must undergo biopsy to determine tumor cell type and chemotherapy. | |||
*GISTs are highly vascular which puts them at a risk of bleeding. | |||
**Percutaneous fine needle biopsy may put the patient at an increased risk of tumor rupture and bleeding. | |||
**Percutaneous biopsy can also lead to tumor seeding along the biopsy tract such as peritoneum or mesentery. | |||
**Thus, patients in whom surgery is an option are advised not to undergo biopsy. | |||
==References== | ==References== | ||
Revision as of 01:41, 18 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
Endoscopy may be helpful in the diagnosis of gastrointestinal stromal tumor (GIST).An endoscope can be used in conditions where GIST is located in accessible places such as stomach, esophagus and large intestine. On an endoscopy, GIST can appear as a smooth submucosal mass with areas of ulceration or bleeding.
Other Imaging Findings
Endoscopy may be helpful in the diagnosis of gastrointestinal stromal tumor (GIST). An endoscope can be used in conditions where GIST is located in accessible places such as stomach, esophagus and large intestine. However, GIST located outside the lumen of wall may not be visible on an endoscopy. Findings on an endoscopy suggestive of GIST include:[1][2][3]
- Smooth submucosal mass
- Areas of ulceration or bleeding
Endoscopic guided biopsy may be done for definite diagnosis of gastrointestinal stromal tumor (GIST). However, percutaneous biopsy is not routinely recommended.
- Patients with unresectable GIST must undergo biopsy to determine tumor cell type and chemotherapy.
- GISTs are highly vascular which puts them at a risk of bleeding.
- Percutaneous fine needle biopsy may put the patient at an increased risk of tumor rupture and bleeding.
- Percutaneous biopsy can also lead to tumor seeding along the biopsy tract such as peritoneum or mesentery.
- Thus, patients in whom surgery is an option are advised not to undergo biopsy.
References
- ↑ Gu M, Ghafari S, Nguyen PT, Lin F (2001). "Cytologic diagnosis of gastrointestinal stromal tumors of the stomach by endoscopic ultrasound-guided fine-needle aspiration biopsy: cytomorphologic and immunohistochemical study of 12 cases". Diagn. Cytopathol. 25 (6): 343–50. PMID 11747229.
- ↑ Fu K, Eloubeidi MA, Jhala NC, Jhala D, Chhieng DC, Eltoum IE (2002). "Diagnosis of gastrointestinal stromal tumor by endoscopic ultrasound-guided fine needle aspiration biopsy--a potential pitfall". Ann Diagn Pathol. 6 (5): 294–301. PMID 12376922.
- ↑ Zhao X, Yue C (2012). "Gastrointestinal stromal tumor". J Gastrointest Oncol. 3 (3): 189–208. doi:10.3978/j.issn.2078-6891.2012.031. PMC 3418531. PMID 22943011.