Non-alcoholic fatty liver disease classification: Difference between revisions
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==Classification== | ==Classification== | ||
* Based on histology it is classified into the non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). | * Based on histology it is classified into the non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH).<ref name="pmid24661406">{{cite journal| author=Hashimoto E, Tokushige K, Ludwig J| title=Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges. | journal=Hepatol Res | year= 2015 | volume= 45 | issue= 1 | pages= 20-8 | pmid=24661406 | doi=10.1111/hepr.12333 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24661406 }} </ref> | ||
* NAFL mostly considered as a benign condition but recent studies show it can progress to NASH up to 44%. | * NAFL mostly considered as a benign condition but recent studies show it can progress to NASH up to 44%. | ||
* The more severe form of NAFLD is called non-alcoholic steatohepatitis (NASH). | * The more severe form of NAFLD is called non-alcoholic steatohepatitis (NASH). | ||
Revision as of 02:08, 18 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
NAFLD may be classified into non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH).
Classification
- Based on histology it is classified into the non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH).[1]
- NAFL mostly considered as a benign condition but recent studies show it can progress to NASH up to 44%.
- The more severe form of NAFLD is called non-alcoholic steatohepatitis (NASH).
- One of the leading cause of cirrhosis in adults in united states is NASH. Almost 25 percent of adults with NASH may lead to cirrhosis.
- On the other hand, NASH progress to fibrosis that can lead to cirrhosis and hepatocellular cancer (HCC).
- Rate of progression does not correlate with body mass index (BMI) or hyperlipidemia
References
- ↑ Hashimoto E, Tokushige K, Ludwig J (2015). "Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges". Hepatol Res. 45 (1): 20–8. doi:10.1111/hepr.12333. PMID 24661406.