Gastrointestinal stromal tumor differential diagnosis: Difference between revisions

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Revision as of 17:10, 18 December 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Gastrointestinal stromal tumor must be differentiated from gastrointestinal leiomyoma, gastrointestinal leiomyosarcoma, gastrointestinal lymphoma / gastric lymphoma, gastrointestinal schwannoma and gastrointestinal carcinoid.

Marker	GIST	GI leiomyoma	GI Leiomyosarcoma	Schwannoma	GI carcinoma	Melanoma
CD117	Positive (95%)	Negative	Negative	Negative	Positive (50%)	Positive
CD34	Positive (70%)	Negative	Negative	Positive (33%)	Negative	negative
DOG 1	Positive (95%)	Negative	Negative	Negative	Negative	Rare
Other Features	Desmin positive in 1-2%	Desmin positive in 100% cases	Desmin positive but variable proportion	GFAP positive	Keratin positive	S100 positive

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{CMG}}{{AE}}{{PSD}}
 {{Gastrointestinal stromal tumor}}
@@ Line 15: / Line 16: @@
 *Gastrointestinal [[carcinoid]]<ref>{{Cite web | title =Gastrointestinal stromal tumour
   | url = http://radiopaedia.org/articles/gastrointestinal-stromal-tumour-1}}</ref>
+{| class="wikitable"
+!Marker
+!GIST
+!GI leiomyoma
+!GI Leiomyosarcoma
+!Schwannoma
+!GI carcinoma
+!Melanoma
+|-
+|CD117
+|Positive (95%)
+|Negative
+|Negative
+|Negative
+|Positive (50%)
+|Positive
+|-
+|CD34
+|Positive (70%)
+|Negative
+|Negative
+|Positive (33%)
+|Negative
+|negative
+|-
+|DOG 1
+|Positive (95%)
+|Negative
+|Negative
+|Negative
+|Negative
+|Rare
+|-
+|Other
+Features
+|Desmin positive
+in 1-2%
+|Desmin positive in
+% cases
+|Desmin positive but
+variable proportion
+|GFAP positive
+|Keratin positive
+|S100 positive
+|-
+|
+|
+|
+|
+|
+|
+|
+|-
+|
+|
+|
+|
+|
+|
+|
+|}
 ==References==