Sandbox: malabsorption: Difference between revisions
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* [[Abdominal tenderness ]] | * [[Abdominal tenderness ]] | ||
* [[Abdominal distention]] | |||
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* Genetic testing | * Genetic testing | ||
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* [[ | * [[Headache]] | ||
* [[ | * [[Vertigo]] | ||
* [[Memory impairment]] | |||
* [[Lethargy]] | |||
* Symptoms begin mainly after ingestion of [[lactose]] | * Symptoms begin mainly after ingestion of [[lactose]] | ||
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* [[Abdominal tenderness]] | * [[Abdominal tenderness]] | ||
* [[ | * [[Abdominal distention]] | ||
* Normal [[Stomach rumble|bowel sounds]] | * Normal [[Stomach rumble|bowel sounds]] | ||
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Revision as of 15:18, 19 December 2017
Differential Diagnosis of Diarrhea
To review the differential diagnosis of diarrhea, click here.
To review the differential diagnosis of acute diarrhea, click here.
To review the differential diagnosis of chronic diarrhea, click here.
To review the differential diagnosis of traveler's diarrhea, click here.
To review the differential diagnosis of acute watery diarrhea, click here.
To review the differential diagnosis of acute bloody diarrhea, click here.
To review the differential diagnosis of acute fatty diarrhea, click here.
To review the differential diagnosis of chronic watery diarrhea, click here.
To review the differential diagnosis of chronic bloody diarrhea, click here.
To review the differential diagnosis of chronic fatty diarrhea, click here.
To review the differential diagnosis of acute diarrhea and fever, click here.
To review the differential diagnosis of chronic diarrhea and fever, click here.
To review the differential diagnosis of acute diarrhea and abdominal pain, click here.
To review the differential diagnosis of chronic diarrhea and abdominal pain, click here.
To review the differential diagnosis of acute diarrhea and weight loss, click here.
To review the differential diagnosis of chronic diarrhea and weight loss, click here.
Diarrhea
The following table outlines the major differential diagnoses of diarrhea.
Abbreviations: GI: Gastrointestinal, CBC: Complete blood count, WBC: White blood cell, RBC: Red blood cell, Plt: Platelet, Hgb: Hemoglobin, ESR: Erythrocyte sedimentation rate, CRP: C–reactive protein, IgE: Immunoglobulin E, IgA: Immunoglobulin A, ETEC: Escherichia coli enteritis, EPEC: Enteropathogenic Escherichia coli, EIEC: Enteroinvasive Escherichia coli, EHEC: Enterohemorrhagic Escherichia coli, EAEC: Enteroaggregative Escherichia coli,
Categories | Cause | Clinical manifestation | Lab findings | Extra intestinal findings | Cause/Pathogenesis | Gold standard diagnosis | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms | GI signs | |||||||||||||||||||||||
Duration | Diarrhea | Fever | Abdominal pain | Weight loss | ||||||||||||||||||||
Stool exam | CBC | Other lab findings | ||||||||||||||||||||||
Acute | Chronic | Watery | Bloody | Fatty | WBC | RBC | Ova/Parasite | Osmotic gap | Other | WBC | Hgb | Plt | ||||||||||||
Gastrointestinal | Crohns disease | – | + | + | + | + | ± | + | + | + | + | – | – | – | ↑ | ↓ | ↑ |
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Ulcerative colitis | – | + | + | + | + | + | + | + |
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+ | + | – | – | – | ↑ | ↓ | ↑ |
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Celiac disease | – | + | ± | – | ± | – | + | + |
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– | – | – | – |
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– | ↓ | – |
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Cystic fibrosis | – | + | – | – | + | ± | + | + | – | – | – | – |
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– | ↓ | – |
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Chronic pancreatitis | – | + | + | – | + | – | + | + | – | – | – | – |
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– | – | – |
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Bile acid malabsorption | – | + | + | – | + | – | – | + | – | – | – | – |
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– | – | – |
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Microscopic colitis | – | + | + | – | – | – | + | + | – | – | – | – | – | – | ↓ | – |
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Infective colitis | – | + | + | + | – | + | + | + |
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+ | + | + | – |
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↑ | ↓ | ↑ | |||||||
Ischemic colitis | + | + | + | + | – | + | + | + |
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+ | + | – | – |
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↑ | ↓ | ↑ |
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Lactose intolerance | + | + | + | – | – | – | + | – | – | – | – | ↑ |
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– | – | – |
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Irritable bowel syndrome | – | + | ± | – | ± | – | ± | – | – | – | – | – |
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– | – | – |
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Infection | Bacterial | Whipple's disease | – | + | + | – | + | ± | + | + | – | – | – | – |
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↓ | ↓ | ↓/↑ |
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Tropical sprue | + | + | + | – | + | + | + | + |
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+ | – | – | – |
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– | ↓ | – |
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Small bowel bacterial overgrowth | – | + | + | – | + | – | + | + | + | – | – | – |
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– | ↓ | – |
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Pseudomembranous enterocolitis | + | – | + | ± | – | + | + | ± | + | + | – | – |
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↑ | ↓ | ↓ |
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Campylobacteriosis | + | – | + | + | – | + | + | – |
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+ | + | – | – |
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↑ | – | – |
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||||||
Salmonellosis | + | + | + | + | – | + | + | – | + | + | – | – |
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↑ | – | ↑ | ||||||||
Shigellosis | + | – | + | + | – | + | + | – |
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+ | + | – | – |
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↑/↓ | ↓ | ↓ |
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||||||
Escherichia coli enteritis | ETEC | + | – | + | – | – | + | – | – |
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+ | – | – | – |
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↑ | – | – |
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|||
EPEC | + | + | + | + | – | + | + | + |
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+ | + | – | – |
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↑ | – | – |
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EIEC | + | – | + | + | – | + | + | – |
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+ | + | – | – |
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↑ | – | – |
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|||||
EHEC | + | – | + | + | – | – | + | – |
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+ | + | – | – |
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↑ | ↓ | ↓ | |||||||
EAEC | + | + | + | + | – | – | + | – |
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+ | + | – | – |
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↑ | ↓ | ↓ |
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|||||
Yersinia enterocolitica | + | – | + | + | – | + | + | – |
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+ | + | – | – |
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↑ | – | – |
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Vibrio cholera | + | – | + | – | – | – | + | – |
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+ | – | – | – |
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↑ | – | – | |||||||
Aeromonas | + | + | + | + | – | + | + | – |
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+ | + | – | – |
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↑ | – | – |
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Plesiomonas | + | – | + | + | – | + | + | – |
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+ | + | – | – |
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↑ | – | – |
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Mycobacterium avium complex | + | + | + | + | – | + | + | – | + | + | – | – |
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↓ | ↓ | – |
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Food poisoning | + | – | + | ± | – | + | + | ± | + | ± | – | – |
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↑ | – | – |
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Virus | Norovirus | + | – | + | – | – | + | + | – | – | – | – | – |
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↓ | – | – |
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| |||||
Rotavirus | + | – | + | – | – | + | – | – |
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+ | – | – | – |
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– | – | – |
| ||||||
Echovirus | + | – | + | – | – | + | + | – | – | – | – | – |
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– | – | – |
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| ||||||
Adenovirus | + | – | + | – | – | + | + | – | – | – | – | – |
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– | – | – |
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CMV colitis | + | + | – | + | – | ± | + | – |
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+ | + | – | – |
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↓ | – | – |
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HIV | – | + | + | – | – | + | + | + | + | – | – | – |
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↓ | ↓ | – |
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Parasite | Entamoeba histolytica | + | + | + | + | – | + | + | – | + | + | + | – |
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↑ | – | – |
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| ||||
Giardia | – | + | + | – | + | – | + | + | – | – | + | – |
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– | – | – | – |
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Cryptosporidium | – | + | + | – | – | – | + | + | – | – | + | – |
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– | – | – |
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Microsporidia | + | + | + | – | – | + | + | – | – | – | + | – |
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– | – | – |
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| ||||||
Isospora | + | + | + | – | + | + | + | + | + | + | + | – |
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↑ | – | – |
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| |||||
Tumors | Carcinoid tumor | – | + | + | + | – | – | + | + | – | + | – | ↓ |
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– | – | – |
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| ||||
VIPoma | + | + | + | – | + | – | + | + |
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– | – | – | ↓ |
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– | – | – |
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|
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Zollinger–Ellison syndrome | – | + | + | + | + | – | + | + | – | – | – | ↓ |
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– | ↓ | – |
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Somatostatinoma | – | + | + | – | – | – | + | + | – | – | – | ↓ |
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– | – | – |
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| |||||
Lymphoma | – | + | + | + | – | + | + | + | – | + | – | – |
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– | ↓ | – |
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| ||||||
Colorectal cancer | – | + | + | + | + | – | + | + |
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– | + | – | – |
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– | ↓ | – |
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| |||||
Medication/Toxicity | Medications | + | + | + | – | ± | ± | + | + | – | – | – | ↑/↓ |
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↑ | – | – |
|
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| ||||
Factitious diarrhea | + | + | + | – | – | – | + | + | – | – | – | ↑/↓ |
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– | – | – |
| |||||||
Heavy metal ingestion | – | + | + | – | – | – | + | + | – | – | – | – |
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– | – | – |
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| ||||||
Organophosphate poisoning | + | + | + | – | – | – | + | – | – | – | – | – |
|
– | – | – |
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|
|
| ||||
Opium withdrawal | + | + | + | – | – | – | + | – |
|
– | – | – | – |
|
– | – | – |
| ||||||
Iatrogenic | Short bowel syndrome | + | + | + | – | + | – | – | + | – | – | – | – |
|
– | ↓ | ↑ |
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|
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| |||
Radiation enteritis | + | + | + | + | + | – | + | + | + | + | – | – |
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– | ↓ | – |
|
|
| |||||
Dumping syndrome | – | + | + | – | + | – | – | + |
|
– | – | – | – | – | – | – | – |
|
| |||||
Others | Abetalipoproteinemia | – | + | + | – | + | – | + | + | – | – | – | – |
|
– | – | – |
|
|
| ||||
Hyperthyroidism | – | + | + | – | – | ± | + | + | – | – | – | – |
|
– | – | – |
|
|
||||||
Diabetic neuropathy | – | + | + | – | + | – | + | + | – | – | – | – |
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– | ↓ | – |
|
| ||||||
Systemic sclerosis | – | + | + | ± | + | – | + | + | – | + | – | – |
|
– | ↓ | – |
|
|