Portal vein thrombosis laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease. Although, [[coagulation factors]] levels could be moderately decreased, while [[D-dimer]] level is usually increased. Im some patients laboratory findings may show moderate increase in serum aminotransferases.<ref name="pmid20066733">{{cite journal |vauthors=Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A |title=Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment |journal=World J. Gastroenterol. |volume=16 |issue=2 |pages=143–55 |year=2010 |pmid=20066733 |pmc=2806552 |doi= |url=}}</ref><ref name="pmid16951667">{{cite journal |vauthors=Condat B, Valla D |title=Nonmalignant portal vein thrombosis in adults |journal=Nat Clin Pract Gastroenterol Hepatol |volume=3 |issue=9 |pages=505–15 |year=2006 |pmid=16951667 |doi=10.1038/ncpgasthep0577 |url=}}</ref><ref name="pmid2806552">{{cite journal |vauthors=Zhang WW, Churchill S, Churchill P |title=Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain |journal=FEBS Lett. |volume=256 |issue=1-2 |pages=71–4 |year=1989 |pmid=2806552 |doi= |url=}}</ref> | *Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease. Although, [[coagulation factors]] levels could be moderately decreased, while [[D-dimer]] level is usually increased. Im some patients laboratory findings may show moderate increase in serum aminotransferases.<ref name="pmid20066733">{{cite journal |vauthors=Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A |title=Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment |journal=World J. Gastroenterol. |volume=16 |issue=2 |pages=143–55 |year=2010 |pmid=20066733 |pmc=2806552 |doi= |url=}}</ref><ref name="pmid16951667">{{cite journal |vauthors=Condat B, Valla D |title=Nonmalignant portal vein thrombosis in adults |journal=Nat Clin Pract Gastroenterol Hepatol |volume=3 |issue=9 |pages=505–15 |year=2006 |pmid=16951667 |doi=10.1038/ncpgasthep0577 |url=}}</ref><ref name="pmid2806552">{{cite journal |vauthors=Zhang WW, Churchill S, Churchill P |title=Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain |journal=FEBS Lett. |volume=256 |issue=1-2 |pages=71–4 |year=1989 |pmid=2806552 |doi= |url=}}</ref> | ||
*In patients with cirrhosis, laboratory findings may demonstrate an elevated bilirubin, low platelet count, prolonged international normalized ratio (INR), or renal insufficiency. | *In patients with cirrhosis, laboratory findings may demonstrate an elevated [[bilirubin]], low [[platelet]] count, prolonged [[international normalized ratio]] (INR), or [[renal insufficiency]]. | ||
*Blood cultures of septic portal vein are often positive for Bacteroides fragilis or Escherichia coli, also other pathogens have been cultured.<ref name="pmid8589130">{{cite journal |vauthors=Plemmons RM, Dooley DP, Longfield RN |title=Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era |journal=Clin. Infect. Dis. |volume=21 |issue=5 |pages=1114–20 |year=1995 |pmid=8589130 |doi= |url=}}</ref> | *Blood cultures of [[septic]] portal vein are often positive for [[Bacteroides fragilis|''Bacteroides fragilis'']] or [[Escherichia coli|''Escherichia coli'']], also other pathogens have been cultured.<ref name="pmid8589130">{{cite journal |vauthors=Plemmons RM, Dooley DP, Longfield RN |title=Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era |journal=Clin. Infect. Dis. |volume=21 |issue=5 |pages=1114–20 |year=1995 |pmid=8589130 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Laboratory finding is usually normal among patients with portal vein thrombosis.
Laboratory Findings
- Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease. Although, coagulation factors levels could be moderately decreased, while D-dimer level is usually increased. Im some patients laboratory findings may show moderate increase in serum aminotransferases.[1][2][3]
- In patients with cirrhosis, laboratory findings may demonstrate an elevated bilirubin, low platelet count, prolonged international normalized ratio (INR), or renal insufficiency.
- Blood cultures of septic portal vein are often positive for Bacteroides fragilis or Escherichia coli, also other pathogens have been cultured.[4]
References
- ↑ Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
- ↑ Condat B, Valla D (2006). "Nonmalignant portal vein thrombosis in adults". Nat Clin Pract Gastroenterol Hepatol. 3 (9): 505–15. doi:10.1038/ncpgasthep0577. PMID 16951667.
- ↑ Zhang WW, Churchill S, Churchill P (1989). "Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain". FEBS Lett. 256 (1–2): 71–4. PMID 2806552.
- ↑ Plemmons RM, Dooley DP, Longfield RN (1995). "Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era". Clin. Infect. Dis. 21 (5): 1114–20. PMID 8589130.