RAB25: Difference between revisions

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Revision as of 17:15, 6 December 2017

Ras-related protein Rab-25 is a protein that in humans is encoded by the RAB25 gene.^[1]^[2] It is thought to act as a promoter of tumor development.^[3]

Interactions

RAB25 has been shown to interact with RAB11FIP2^[4]^[5] and RAB11FIP5.^[4]^[5]

References

↑ Pereira-Leal JB, Seabra MC (November 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
↑ "Entrez Gene: RAB25 RAB25, member RAS oncogene family".
↑ Kessler, D; Gruen, GC; Heider, D; Morgner, J; Reis, H; Schmid, KW; Jendrossek, V (2012). "The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration". Cellular Physiology and Biochemistry. 29 (5–6): 647–56. doi:10.1159/000295249. PMID 22613965.
↑ ^4.0 ^4.1 Hales, C M; Griner R; Hobdy-Henderson K C; Dorn M C; Hardy D; Kumar R; Navarre J; Chan E K; Lapierre L A; Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. United States. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. ISSN 0021-9258. PMID 11495908.
↑ ^5.0 ^5.1 Prekeris, R; Davies J M; Scheller R H (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. United States. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. ISSN 0021-9258. PMID 11481332.

Goldenring JR, Shen KR, Vaughan HD, Modlin IM (1993). "Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung". J. Biol. Chem. 268 (25): 18419–22. PMID 8360141.
Ray GS, Lee JR, Nwokeji K, et al. (1997). "Increased immunoreactivity for Rab11, a small GTP-binding protein, in low-grade dysplastic Barrett's epithelia". Lab. Invest. 77 (5): 503–11. PMID 9389793.
Lapierre LA, Kumar R, Hales CM, et al. (2001). "Myosin vb is associated with plasma membrane recycling systems". Mol. Biol. Cell. 12 (6): 1843–57. doi:10.1091/mbc.12.6.1843. PMC 37346. PMID 11408590.
Prekeris R, Davies JM, Scheller RH (2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. PMID 11481332.
Hales CM, Griner R, Hobdy-Henderson KC, et al. (2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. PMID 11495908.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMC 311163. PMID 11591653.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Fan Y, Xin XY, Chen BL, Ma X (2007). "Knockdown of RAB25 expression by RNAi inhibits growth of human epithelial ovarian cancer cells in vitro and in vivo". Pathology. 38 (6): 561–7. doi:10.1080/00313020601024037. PMID 17393986.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid11697911-1] Pereira-Leal JB, Seabra MC (November 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.

[entrez-2] "Entrez Gene: RAB25 RAB25, member RAS oncogene family".

[3] Kessler, D; Gruen, GC; Heider, D; Morgner, J; Reis, H; Schmid, KW; Jendrossek, V (2012). "The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration". Cellular Physiology and Biochemistry. 29 (5–6): 647–56. doi:10.1159/000295249. PMID 22613965.

[pmid11495908-4] 4.0 ^4.1 Hales, C M; Griner R; Hobdy-Henderson K C; Dorn M C; Hardy D; Kumar R; Navarre J; Chan E K; Lapierre L A; Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. United States. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. ISSN 0021-9258. PMID 11495908.

[pmid11481332-5] 5.0 ^5.1 Prekeris, R; Davies J M; Scheller R H (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. United States. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. ISSN 0021-9258. PMID 11481332.

[1]

[2]

[3]

[4]

[5]

@@ Line 1: / Line 1: @@
+{{Infobox_gene}}
+'''Ras-related protein Rab-25''' is a [[protein]] that in humans is encoded by the ''RAB25'' [[gene]].<ref name="pmid11697911">{{cite journal |vauthors=Pereira-Leal JB, Seabra MC | title = Evolution of the Rab family of small GTP-binding proteins | journal = J Mol Biol | volume = 313 | issue = 4 | pages = 889–901 |date=November 2001 | pmid = 11697911 | pmc =  | doi = 10.1006/jmbi.2001.5072 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB25 RAB25, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57111| accessdate = }}</ref>
+It is thought to act as a promoter of tumor development.<ref>{{cite journal|last1=Kessler|first1=D|last2=Gruen|first2=GC|last3=Heider|first3=D|last4=Morgner|first4=J|last5=Reis|first5=H|last6=Schmid|first6=KW|last7=Jendrossek|first7=V|title=The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration.|journal=Cellular Physiology and Biochemistry|date=2012|volume=29|issue=5-6|pages=647–56|pmid=22613965|doi=10.1159/000295249}}</ref>
+<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+{{PBB_Summary
+| section_title =
+| summary_text =
+}}
+==Interactions==
+RAB25 has been shown to [[Protein-protein interaction|interact]] with [[RAB11FIP2]]<ref name=pmid11495908>{{cite journal |last=Hales |first=C M |authorlink= |author2=Griner R |author3=Hobdy-Henderson K C |author4=Dorn M C |author5=Hardy D |author6=Kumar R |author7=Navarre J |author8=Chan E K |author9=Lapierre L A |author10=Goldenring J R  |date=October 2001 |title=Identification and characterization of a family of Rab11-interacting proteins |journal=J. Biol. Chem. |volume=276 |issue=42 |pages=39067–75 |publisher= |location = United States| issn = 0021-9258| pmid = 11495908 |doi = 10.1074/jbc.M104831200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11481332>{{cite journal |last=Prekeris |first=R |authorlink= |author2=Davies J M |author3=Scheller R H  |date=October 2001 |title=Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins |journal=J. Biol. Chem. |volume=276 |issue=42 |pages=38966–70 |publisher= |location = United States| issn = 0021-9258| pmid = 11481332 |doi = 10.1074/jbc.M106133200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[RAB11FIP5]].<ref name=pmid11495908/><ref name=pmid11481332/>
+==References==
+{{Reflist}}
+==Further reading==
+{{Refbegin | 2}}
+{{PBB_Further_reading
+| citations =
+*{{cite journal  |vauthors=Goldenring JR, Shen KR, Vaughan HD, Modlin IM |title=Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung. |journal=J. Biol. Chem. |volume=268 |issue= 25 |pages= 18419–22 |year= 1993 |pmid= 8360141 |doi=  }}
+*{{cite journal   |vauthors=Ray GS, Lee JR, Nwokeji K, etal |title=Increased immunoreactivity for Rab11, a small GTP-binding protein, in low-grade dysplastic Barrett's epithelia. |journal=Lab. Invest. |volume=77 |issue= 5 |pages= 503–11 |year= 1997 |pmid= 9389793 |doi=  }}
+*{{cite journal   |vauthors=Lapierre LA, Kumar R, Hales CM, etal |title=Myosin vb is associated with plasma membrane recycling systems. |journal=Mol. Biol. Cell |volume=12 |issue= 6 |pages= 1843–57 |year= 2001 |pmid= 11408590 |doi=  10.1091/mbc.12.6.1843| pmc=37346  }}
+*{{cite journal  |vauthors=Prekeris R, Davies JM, Scheller RH |title=Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 38966–70 |year= 2001 |pmid= 11481332 |doi= 10.1074/jbc.M106133200 }}
+*{{cite journal   |vauthors=Hales CM, Griner R, Hobdy-Henderson KC, etal |title=Identification and characterization of a family of Rab11-interacting proteins. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 39067–75 |year= 2001 |pmid= 11495908 |doi= 10.1074/jbc.M104831200 }}
+*{{cite journal   |vauthors=Suzuki H, Fukunishi Y, Kagawa I, etal |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101  | pmc=311163 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
+*{{cite journal   |vauthors=Barrios-Rodiles M, Brown KR, Ozdamar B, etal |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
+*{{cite journal   |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  | pmc=1847948 }}
+*{{cite journal  |vauthors=Fan Y, Xin XY, Chen BL, Ma X |title=Knockdown of RAB25 expression by RNAi inhibits growth of human epithelial ovarian cancer cells in vitro and in vivo. |journal=Pathology |volume=38 |issue= 6 |pages= 561–7 |year= 2007 |pmid= 17393986 |doi=10.1080/00313020601024037  }}
+}}
+{{Refend}}
+{{PDB Gallery|geneid=57111}}
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 {{PBB_Controls
 | update_page = yes
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@@ Line 8: / Line 41: @@
 }}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image = PBB_Protein_RAB25_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 2oil.
- | PDB = {{PDB2|2oil}}
- | Name = RAB25, member RAS oncogene family
- | HGNCid = 18238
- | Symbol = RAB25
- | AltSymbols =; CATX-8
- | OMIM =
- | ECnumber =
- | Homologene = 22995
- | MGIid = 1858203
- | GeneAtlas_image1 = PBB_GE_RAB25_218186_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
- | Component = {{GNF_GO|id=GO:0016020 |text = membrane}}
- | Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 57111
-    | Hs_Ensembl = ENSG00000132698
-    | Hs_RefseqProtein = NP_065120
-    | Hs_RefseqmRNA = NM_020387
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 1
-    | Hs_GenLoc_start = 154297575
-    | Hs_GenLoc_end = 154306920
-    | Hs_Uniprot = P57735
-    | Mm_EntrezGene = 53868
-    | Mm_Ensembl = ENSMUSG00000008601
-    | Mm_RefseqmRNA = NM_016899
-    | Mm_RefseqProtein = NP_058595
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 3
-    | Mm_GenLoc_start = 88627956
-    | Mm_GenLoc_end = 88634206
-    | Mm_Uniprot = Q0PD30
-  }}
-}}
-'''RAB25, member RAS oncogene family''', also known as '''RAB25''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB25 RAB25, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57111| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
-{{reflist|2}}
-==Further reading==
-{{refbegin | 2}}
-{{PBB_Further_reading
-| citations =
-*{{cite journal  | author=Goldenring JR, Shen KR, Vaughan HD, Modlin IM |title=Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung. |journal=J. Biol. Chem. |volume=268 |issue= 25 |pages= 18419-22 |year= 1993 |pmid= 8360141 |doi=  }}
-*{{cite journal  | author=Ray GS, Lee JR, Nwokeji K, ''et al.'' |title=Increased immunoreactivity for Rab11, a small GTP-binding protein, in low-grade dysplastic Barrett's epithelia. |journal=Lab. Invest. |volume=77 |issue= 5 |pages= 503-11 |year= 1997 |pmid= 9389793 |doi=  }}
-*{{cite journal  | author=Lapierre LA, Kumar R, Hales CM, ''et al.'' |title=Myosin vb is associated with plasma membrane recycling systems. |journal=Mol. Biol. Cell |volume=12 |issue= 6 |pages= 1843-57 |year= 2001 |pmid= 11408590 |doi=  }}
-*{{cite journal  | author=Prekeris R, Davies JM, Scheller RH |title=Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 38966-70 |year= 2001 |pmid= 11481332 |doi= 10.1074/jbc.M106133200 }}
-*{{cite journal  | author=Hales CM, Griner R, Hobdy-Henderson KC, ''et al.'' |title=Identification and characterization of a family of Rab11-interacting proteins. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 39067-75 |year= 2001 |pmid= 11495908 |doi= 10.1074/jbc.M104831200 }}
-*{{cite journal  | author=Suzuki H, Fukunishi Y, Kagawa I, ''et al.'' |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758-65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101 }}
-*{{cite journal  | author=Pereira-Leal JB, Seabra MC |title=Evolution of the Rab family of small GTP-binding proteins. |journal=J. Mol. Biol. |volume=313 |issue= 4 |pages= 889-901 |year= 2001 |pmid= 11697911 |doi= 10.1006/jmbi.2001.5072 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Barrios-Rodiles M, Brown KR, Ozdamar B, ''et al.'' |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621-5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
-*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
-*{{cite journal  | author=Fan Y, Xin XY, Chen BL, Ma X |title=Knockdown of RAB25 expression by RNAi inhibits growth of human epithelial ovarian cancer cells in vitro and in vivo. |journal=Pathology |volume=38 |issue= 6 |pages= 561-7 |year= 2007 |pmid= 17393986 |doi=  }}
-}}
-{{refend}}
-{{protein-stub}}
+{{Gene-1-stub}}
-{{WikiDoc Sources}}

RAB25: Difference between revisions

Revision as of 17:15, 6 December 2017

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