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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Vesicle-trafficking protein SEC22b''' is a [[protein]] that in humans is encoded by the ''SEC22B'' [[gene]].<ref name="pmid9094723">{{cite journal | vauthors = Hay JC, Chao DS, Kuo CS, Scheller RH | title = Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells | journal = Cell | volume = 89 | issue = 1 | pages = 149–58 | date = April 1997 | pmid = 9094723 | pmc =  | doi = 10.1016/S0092-8674(00)80191-9 }}</ref><ref name="pmid16354670">{{cite journal | vauthors = Okumura AJ, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, Nagao K, Nishikawa M, Yoshimura A, Wada I | title = Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system | journal = The Journal of Biological Chemistry | volume = 281 | issue = 7 | pages = 4495–506 | date = February 2006 | pmid = 16354670 | pmc = | doi = 10.1074/jbc.M509715200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9554| accessdate = }}</ref>
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| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image = PBB_Protein_SEC22B_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1ifq.
| PDB = {{PDB2|1ifq}}, {{PDB2|2nup}}, {{PDB2|2nut}}
| Name = SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
| HGNCid = 10700
| Symbol = SEC22B
| AltSymbols =; ERS-24; SEC22L1
| OMIM = 604029
| ECnumber = 
| Homologene = 3597
| MGIid = 1338759
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005789 |text = endoplasmic reticulum membrane}} {{GNF_GO|id=GO:0005793 |text = ER-Golgi intermediate compartment}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006888 |text = ER to Golgi vesicle-mediated transport}} {{GNF_GO|id=GO:0015031 |text = protein transport}} {{GNF_GO|id=GO:0016192 |text = vesicle-mediated transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9554
    | Hs_Ensembl = 
    | Hs_RefseqProtein = NP_004883
    | Hs_RefseqmRNA = NM_004892
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 20333
    | Mm_Ensembl = ENSMUSG00000027879
    | Mm_RefseqmRNA = NM_011342
    | Mm_RefseqProtein = NP_035472
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 97986632
    | Mm_GenLoc_end = 98007723
    | Mm_Uniprot = Q3UZ06
  }}
}}
'''SEC22 vesicle trafficking protein homolog B (S. cerevisiae)''', also known as '''SEC22B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9554| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.<ref name="entrez" /> SEC22B has been shown to interact with syntaxin 18.
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.<ref name="entrez">{{cite web | title = Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9554| accessdate = }}</ref>
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF | title = Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes | journal = Journal of Proteome Research | volume = 5 | issue = 11 | pages = 3135–44 | date = November 2006 | pmid = 17081065 | doi = 10.1021/pr060363j }}
| citations =
* {{cite journal | vauthors = Breuza L, Halbeisen R, Jenö P, Otte S, Barlowe C, Hong W, Hauri HP | title = Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46 | journal = The Journal of Biological Chemistry | volume = 279 | issue = 45 | pages = 47242–53 | date = November 2004 | pmid = 15308636 | doi = 10.1074/jbc.M406644200 }}
*{{cite journal | author=Chi A, Valencia JC, Hu ZZ, ''et al.'' |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135-44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j }}
* {{cite journal | vauthors = Nakajima K, Hirose H, Taniguchi M, Kurashina H, Arasaki K, Nagahama M, Tani K, Yamamoto A, Tagaya M | title = Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion | journal = The EMBO Journal | volume = 23 | issue = 16 | pages = 3216–26 | date = August 2004 | pmid = 15272311 | pmc = 514507 | doi = 10.1038/sj.emboj.7600333 }}
*{{cite journal | author=Okumura AJ, Hatsuzawa K, Tamura T, ''et al.'' |title=Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system. |journal=J. Biol. Chem. |volume=281 |issue= 7 |pages= 4495-506 |year= 2006 |pmid= 16354670 |doi= 10.1074/jbc.M509715200 }}
* {{cite journal | vauthors = Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL | title = Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes | journal = Genomics | volume = 84 | issue = 1 | pages = 205–10 | date = July 2004 | pmid = 15203218 | doi = 10.1016/j.ygeno.2004.01.011 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
* {{cite journal | vauthors = Hirose H, Arasaki K, Dohmae N, Takio K, Hatsuzawa K, Nagahama M, Tani K, Yamamoto A, Tohyama M, Tagaya M | title = Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi | journal = The EMBO Journal | volume = 23 | issue = 6 | pages = 1267–78 | date = March 2004 | pmid = 15029241 | pmc = 381410 | doi = 10.1038/sj.emboj.7600135 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
* {{cite journal | vauthors = Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Research | volume = 10 | issue = 10 | pages = 1546–60 | date = October 2000 | pmid = 11042152 | pmc = 310934 | doi = 10.1101/gr.140200 }}
*{{cite journal  | author=Breuza L, Halbeisen R, Jenö P, ''et al.'' |title=Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46. |journal=J. Biol. Chem. |volume=279 |issue= 45 |pages= 47242-53 |year= 2004 |pmid= 15308636 |doi= 10.1074/jbc.M406644200 }}
* {{cite journal | vauthors = Xu D, Joglekar AP, Williams AL, Hay JC | title = Subunit structure of a mammalian ER/Golgi SNARE complex | journal = The Journal of Biological Chemistry | volume = 275 | issue = 50 | pages = 39631–9 | date = December 2000 | pmid = 11035026 | doi = 10.1074/jbc.M007684200 }}
*{{cite journal | author=Nakajima K, Hirose H, Taniguchi M, ''et al.'' |title=Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. |journal=EMBO J. |volume=23 |issue= 16 |pages= 3216-26 |year= 2005 |pmid= 15272311 |doi= 10.1038/sj.emboj.7600333 }}
* {{cite journal | vauthors = Parlati F, McNew JA, Fukuda R, Miller R, Söllner TH, Rothman JE | title = Topological restriction of SNARE-dependent membrane fusion | journal = Nature | volume = 407 | issue = 6801 | pages = 194–8 | date = September 2000 | pmid = 11001058 | doi = 10.1038/35025076 }}
*{{cite journal | author=Fu GK, Wang JT, Yang J, ''et al.'' |title=Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. |journal=Genomics |volume=84 |issue= 1 |pages= 205-10 |year= 2005 |pmid= 15203218 |doi= 10.1016/j.ygeno.2004.01.011 }}
* {{cite journal | vauthors = Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG, Shen Y, Gu J, Yu YP, Xu SH, Wang YX, Chen SJ, Chen Z | title = Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 14 | pages = 8175–80 | date = July 1998 | pmid = 9653160 | pmc = 20949 | doi = 10.1073/pnas.95.14.8175 }}
*{{cite journal | author=Hirose H, Arasaki K, Dohmae N, ''et al.'' |title=Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. |journal=EMBO J. |volume=23 |issue= 6 |pages= 1267-78 |year= 2005 |pmid= 15029241 |doi= 10.1038/sj.emboj.7600135 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Zhang QH, Ye M, Wu XY, ''et al.'' |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546-60 |year= 2001 |pmid= 11042152 |doi= }}
*{{cite journal | author=Xu D, Joglekar AP, Williams AL, Hay JC |title=Subunit structure of a mammalian ER/Golgi SNARE complex. |journal=J. Biol. Chem. |volume=275 |issue= 50 |pages= 39631-9 |year= 2001 |pmid= 11035026 |doi= 10.1074/jbc.M007684200 }}
*{{cite journal | author=Parlati F, McNew JA, Fukuda R, ''et al.'' |title=Topological restriction of SNARE-dependent membrane fusion. |journal=Nature |volume=407 |issue= 6801 |pages= 194-8 |year= 2000 |pmid= 11001058 |doi= 10.1038/35025076 }}
*{{cite journal | author=Mao M, Fu G, Wu JS, ''et al.'' |title=Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 14 |pages= 8175-80 |year= 1998 |pmid= 9653160 |doi= }}
*{{cite journal  | author=Hay JC, Chao DS, Kuo CS, Scheller RH |title=Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. |journal=Cell |volume=89 |issue= 1 |pages= 149-58 |year= 1997 |pmid= 9094723 |doi=  }}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=9554}}


{{protein-stub}}
{{protein-stub}}
{{WikiDoc Sources}}

Latest revision as of 03:09, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene.[1][2][3]

Function

The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.[3] SEC22B has been shown to interact with syntaxin 18.

References

  1. ↑ Hay JC, Chao DS, Kuo CS, Scheller RH (April 1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell. 89 (1): 149–58. doi:10.1016/S0092-8674(00)80191-9. PMID 9094723.
  2. ↑ Okumura AJ, Hatsuzawa K, Tamura T, Nagaya H, Saeki K, Okumura F, Nagao K, Nishikawa M, Yoshimura A, Wada I (February 2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system". The Journal of Biological Chemistry. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670.
  3. ↑ 3.0 3.1 "Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)".

Further reading

Retrieved from "https://www.wikidoc.org/index.php?title=SEC22B&oldid=1411151"