MPZL1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Myelin protein zero-like protein 1''' is a [[protein]] that in humans is encoded by the ''MPZL1'' [[gene]].<ref name="pmid9792637">{{cite journal |vauthors=Zhao ZJ, Zhao R | title = Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2 | journal = J Biol Chem | volume = 273 | issue = 45 | pages = 29367–72 |date=Dec 1998 | pmid = 9792637 | pmc =  | doi =10.1074/jbc.273.45.29367 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MPZL1 myelin protein zero-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9019| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Myelin protein zero-like 1
| HGNCid = 7226
| Symbol = MPZL1
| AltSymbols =; FLJ21047; PZR; PZR1b; PZRa; PZRb
| OMIM = 604376
| ECnumber = 
| Homologene = 2939
| MGIid = 1915731
| GeneAtlas_image1 = PBB_GE_MPZL1_201874_at_tn.png
| GeneAtlas_image2 = PBB_GE_MPZL1_201875_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_MPZL1_210087_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007169 |text = transmembrane receptor protein tyrosine kinase signaling pathway}} {{GNF_GO|id=GO:0007267 |text = cell-cell signaling}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9019
    | Hs_Ensembl = ENSG00000197965
    | Hs_RefseqProtein = NP_003944
    | Hs_RefseqmRNA = NM_003953
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 165957832
    | Hs_GenLoc_end = 166026682
    | Hs_Uniprot = O95297
    | Mm_EntrezGene = 68481
    | Mm_Ensembl = ENSMUSG00000026566
    | Mm_RefseqmRNA = NM_001001880
    | Mm_RefseqProtein = NP_001001880
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 167441281
    | Mm_GenLoc_end = 167471068
    | Mm_Uniprot = Q3TEW6
  }}
}}
'''Myelin protein zero-like 1''', also known as '''MPZL1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MPZL1 myelin protein zero-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9019| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Zhao ZJ, Zhao R |title=Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2. |journal=J. Biol. Chem. |volume=273 |issue= 45 |pages= 29367-72 |year= 1998 |pmid= 9792637 |doi=  }}
*{{cite journal  |vauthors=Zhao R, Zhao ZJ |title=Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs. |journal=J. Biol. Chem. |volume=275 |issue= 8 |pages= 5453–9 |year= 2000 |pmid= 10681522 |doi=10.1074/jbc.275.8.5453 }}
*{{cite journal  | author=Zhao R, Zhao ZJ |title=Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs. |journal=J. Biol. Chem. |volume=275 |issue= 8 |pages= 5453-9 |year= 2000 |pmid= 10681522 |doi=  }}
*{{cite journal  |vauthors=Zhao R, Guerrah A, Tang H, Zhao ZJ |title=Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 7882–8 |year= 2002 |pmid= 11751924 |doi= 10.1074/jbc.M111914200 }}
*{{cite journal  | author=Zhao R, Guerrah A, Tang H, Zhao ZJ |title=Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 7882-8 |year= 2002 |pmid= 11751924 |doi= 10.1074/jbc.M111914200 }}
*{{cite journal   |vauthors=Tang DS, Yu KP, Tang XX, etal |title=Cloning of Human Myelin Protein Zero-like Genes by Bioinformatics Strategy. |journal= Sheng wu hua xue yu sheng wu wu li xue bao [[Acta Biochimica et Biophysica Sinica]]|volume=32 |issue= 4 |pages= 364–368 |year=  2000|pmid= 12075424 |doi=  }}
*{{cite journal | author=Tang DS, Yu KP, Tang XX, ''et al.'' |title=Cloning of Human Myelin Protein Zero-like Genes by Bioinformatics Strategy. |journal= |volume=32 |issue= 4 |pages= 364-368 |year=  |pmid= 12075424 |doi=  }}
*{{cite journal   |vauthors=Wistow G, Bernstein SL, Wyatt MK, etal |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue=  |pages= 205–20 |year= 2002 |pmid= 12107410 |doi=  }}
*{{cite journal | author=Wistow G, Bernstein SL, Wyatt MK, ''et al.'' |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue=  |pages= 205-20 |year= 2002 |pmid= 12107410 |doi=  }}
*{{cite journal   |vauthors=Zannettino AC, Roubelakis M, Welldon KJ, etal |title=Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. |journal=Biochem. J. |volume=370 |issue= Pt 2 |pages= 537–49 |year= 2003 |pmid= 12410637 |doi= 10.1042/BJ20020935 | pmc=1223174 }}
*{{cite journal | author=Zannettino AC, Roubelakis M, Welldon KJ, ''et al.'' |title=Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. |journal=Biochem. J. |volume=370 |issue= Pt 2 |pages= 537-49 |year= 2003 |pmid= 12410637 |doi= 10.1042/BJ20020935 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  |vauthors=Zhao R, Zhao ZJ |title=Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs. |journal=Biochem. Biophys. Res. Commun. |volume=303 |issue= 4 |pages= 1028–33 |year= 2003 |pmid= 12684038 |doi=10.1016/S0006-291X(03)00484-4 }}
*{{cite journal  | author=Zhao R, Zhao ZJ |title=Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs. |journal=Biochem. Biophys. Res. Commun. |volume=303 |issue= 4 |pages= 1028-33 |year= 2003 |pmid= 12684038 |doi=  }}
*{{cite journal   |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal  |vauthors=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 | pmc=442147 }}
*{{cite journal  | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315-23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Blanchetot C, Chagnon M, Dubé N, etal |title=Substrate-trapping techniques in the identification of cellular PTP targets. |journal=Methods |volume=35 |issue= 1 |pages= 44–53 |year= 2005 |pmid= 15588985 |doi= 10.1016/j.ymeth.2004.07.007 }}
*{{cite journal | author=Blanchetot C, Chagnon M, Dubé N, ''et al.'' |title=Substrate-trapping techniques in the identification of cellular PTP targets. |journal=Methods |volume=35 |issue= 1 |pages= 44-53 |year= 2005 |pmid= 15588985 |doi= 10.1016/j.ymeth.2004.07.007 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal   |vauthors=He G, Liu X, Qin W, etal |title=MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese. |journal=Mol. Psychiatry |volume=11 |issue= 8 |pages= 748–51 |year= 2006 |pmid= 16702974 |doi= 10.1038/sj.mp.4001841 }}
*{{cite journal | author=He G, Liu X, Qin W, ''et al.'' |title=MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese. |journal=Mol. Psychiatry |volume=11 |issue= 8 |pages= 748-51 |year= 2006 |pmid= 16702974 |doi= 10.1038/sj.mp.4001841 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 06:48, 4 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Myelin protein zero-like protein 1 is a protein that in humans is encoded by the MPZL1 gene.[1][2]


References

  1. ↑ Zhao ZJ, Zhao R (Dec 1998). "Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2". J Biol Chem. 273 (45): 29367–72. doi:10.1074/jbc.273.45.29367. PMID 9792637.
  2. ↑ "Entrez Gene: MPZL1 myelin protein zero-like 1".

Further reading



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