SSX2IP: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Afadin- and alpha-actinin-binding protein''' is a [[protein]] that in humans is encoded by the ''SSX2IP'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SSX2IP synovial sarcoma, X breakpoint 2 interacting protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117178| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Synovial sarcoma, X breakpoint 2 interacting protein
| HGNCid = 16509
| Symbol = SSX2IP
| AltSymbols =; ADIP; FLJ10848; KIAA0923; MGC75026
| OMIM = 608690
| ECnumber = 
| Homologene = 8522
| MGIid = 2139150
| GeneAtlas_image1 = PBB_GE_SSX2IP_203015_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_SSX2IP_203016_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_SSX2IP_203017_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0043234 |text = protein complex}}
| Process = {{GNF_GO|id=GO:0007155 |text = cell adhesion}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 117178
    | Hs_Ensembl = ENSG00000117155
    | Hs_RefseqProtein = NP_054740
    | Hs_RefseqmRNA = NM_014021
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 84881978
    | Hs_GenLoc_end = 84928816
    | Hs_Uniprot = Q9Y2D8
    | Mm_EntrezGene = 99167
    | Mm_Ensembl = ENSMUSG00000036825
    | Mm_RefseqmRNA = XM_979379
    | Mm_RefseqProtein = XP_984473
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 146342041
    | Mm_GenLoc_end = 146377521
    | Mm_Uniprot = Q69ZV4
  }}
}}
'''Synovial sarcoma, X breakpoint 2 interacting protein''', also known as '''SSX2IP''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SSX2IP synovial sarcoma, X breakpoint 2 interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117178| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
SSX2IP has been shown to [[Protein-protein interaction|interact]] with [[MLLT4]]<ref name=pmid12446711>{{cite journal | vauthors = Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, Takeuchi M, Takai Y | title = ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions | journal = The Journal of Biological Chemistry | volume = 278 | issue = 6 | pages = 4103–11 | date = February 2003 | pmid = 12446711 | doi = 10.1074/jbc.M209832200 }}</ref> and [[Actinin, alpha 1]].<ref name=pmid12446711/>
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| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 6 | issue = 1 | pages = 63–70 | date = February 1999 | pmid = 10231032 | doi = 10.1093/dnares/6.1.63 }}
| citations =
* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = November 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
*{{cite journal | author=Nagase T, Ishikawa K, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 1 |pages= 63-70 |year= 1999 |pmid= 10231032 |doi= }}
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = March 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
*{{cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi= }}
* {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Reports | volume = 1 | issue = 3 | pages = 287–92 | date = September 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
* {{cite journal | vauthors = de Bruijn DR, dos Santos NR, Kater-Baats E, Thijssen J, van den Berk L, Stap J, Balemans M, Schepens M, Merkx G, van Kessel AG | title = The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP | journal = Genes, Chromosomes & Cancer | volume = 34 | issue = 3 | pages = 285–98 | date = July 2002 | pmid = 12007189 | doi = 10.1002/gcc.10073 }}
*{{cite journal | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
* {{cite journal | vauthors = Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, Takeuchi M, Takai Y | title = ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions | journal = The Journal of Biological Chemistry | volume = 278 | issue = 6 | pages = 4103–11 | date = February 2003 | pmid = 12446711 | doi = 10.1074/jbc.M209832200 }}
*{{cite journal | author=de Bruijn DR, dos Santos NR, Kater-Baats E, ''et al.'' |title=The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. |journal=Genes Chromosomes Cancer |volume=34 |issue= 3 |pages= 285-98 |year= 2002 |pmid= 12007189 |doi= 10.1002/gcc.10073 }}
* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = October 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
*{{cite journal | author=Asada M, Irie K, Morimoto K, ''et al.'' |title=ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions. |journal=J. Biol. Chem. |volume=278 |issue= 6 |pages= 4103-11 |year= 2003 |pmid= 12446711 |doi= 10.1074/jbc.M209832200 }}
* {{cite journal | vauthors = Guinn BA, Bland EA, Lodi U, Liggins AP, Tobal K, Petters S, Wells JW, Banham AH, Mufti GJ | title = Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia | journal = Biochemical and Biophysical Research Communications | volume = 335 | issue = 4 | pages = 1293–304 | date = October 2005 | pmid = 16112646 | doi = 10.1016/j.bbrc.2005.08.024 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = January 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
* {{cite journal | vauthors = Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R | title = Phosphoproteome analysis of the human mitotic spindle | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 14 | pages = 5391–6 | date = April 2006 | pmid = 16565220 | pmc = 1459365 | doi = 10.1073/pnas.0507066103 }}
*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal | author=Guinn BA, Bland EA, Lodi U, ''et al.'' |title=Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. |journal=Biochem. Biophys. Res. Commun. |volume=335 |issue= 4 |pages= 1293-304 |year= 2005 |pmid= 16112646 |doi= 10.1016/j.bbrc.2005.08.024 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
*{{cite journal | author=Nousiainen M, Silljé HH, Sauer G, ''et al.'' |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391-6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 }}
}}
{{refend}}
{{refend}}


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Revision as of 07:07, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene.[1]

Interactions

SSX2IP has been shown to interact with MLLT4[2] and Actinin, alpha 1.[2]

References

  1. ↑ "Entrez Gene: SSX2IP synovial sarcoma, X breakpoint 2 interacting protein".
  2. ↑ 2.0 2.1 Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, Takeuchi M, Takai Y (February 2003). "ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions". The Journal of Biological Chemistry. 278 (6): 4103–11. doi:10.1074/jbc.M209832200. PMID 12446711.

Further reading

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