PUM2: Difference between revisions

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Latest revision as of 19:00, 7 September 2017

Pumilio homolog 2 is an RNA-binding protein that in humans is encoded by the PUM2 gene.^[1]^[2]^[3]^[4]

Interactions

BRCA1 has been shown to interact with the following proteins:

References

↑ Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (May 1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
↑ Spassov DS, Jurecic R (Dec 2002). "Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins". Gene. 299 (1–2): 195–204. doi:10.1016/S0378-1119(02)01060-0. PMID 12459267.
↑ Moore FL, Jaruzelska J, Fox MS, Urano J, Firpo MT, Turek PJ, Dorfman DM, Pera RA (Jan 2003). "Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-Like proteins". Proc Natl Acad Sci U S A. 100 (2): 538–43. doi:10.1073/pnas.0234478100. PMC 141031. PMID 12511597.
↑ "Entrez Gene: PUM2 pumilio homolog 2 (Drosophila)".
↑ Campbell ZT, Menichelli E, Friend K, Wu J, Kimble J, Williamson JR, Wickens M (2012). "Identification of a conserved interface between PUF and CPEB proteins". J Biol Chem. 287 (22): 18854–62. doi:10.1074/jbc.M112.352815. PMC 3365739. PMID 22496444.
↑ Ota R, Kotani T, Yamashita M (2011). "Biochemical characterization of Pumilio1 and Pumilio2 in Xenopus oocytes". J Biol Chem. 286 (4): 2853–63. doi:10.1074/jbc.M110.155523. PMC 3024781. PMID 21098481.
↑ Haston KM, Tung JY, Reijo Pera RA (2009). "Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro". PLOS ONE. 4 (5): e5654. doi:10.1371/journal.pone.0005654. PMC 2681483. PMID 19468308.
↑ Geyer CB, Saba R, Kato Y, Anderson AJ, Chappell VK, Saga Y, Eddy EM (2012). "Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male". Biol Reprod. 86 (4): 127. doi:10.1095/biolreprod.111.094938. PMC 3338663. PMID 22190708.

Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Spik A, Oczkowski S, Olszak A, Kotecki M, Formanowicz P, Błazewicz J, Jaruzelska J (2006). "Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line". Reproductive biology. 6 Suppl 1: 37–42. PMID 16967088.
Nakayama M, Kikuno R, Ohara O (2003). "Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC 187542. PMID 12421765.
Jaruzelska J, Kotecki M, Kusz K, Spik A, Firpo M, Reijo Pera RA (2004). "Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells". Dev. Genes Evol. 213 (3): 120–6. doi:10.1007/s00427-003-0303-2. PMID 12690449.
Dazard JE, Gal H, Amariglio N, Rechavi G, Domany E, Givol D (2003). "Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer". Oncogene. 22 (19): 2993–3006. doi:10.1038/sj.onc.1206537. PMID 12771951.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Fox M, Urano J, Reijo Pera RA (2005). "Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind". Genomics. 85 (1): 92–105. doi:10.1016/j.ygeno.2004.10.003. PMID 15607425.
Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW (2005). "P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA". J. Cell. Physiol. 204 (1): 99–105. doi:10.1002/jcp.20263. PMID 15617101.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Kusz K, Ginter-Matuszewska B, Ziolkowska K, Spik A, Bierla J, Jedrzejczak P, Latos-Bielenska A, Pawelczyk L, Jaruzelska J (2007). "Polymorphisms of the human PUMILIO2 gene and male sterility". Mol. Reprod. Dev. 74 (6): 795–9. doi:10.1002/mrd.20683. PMID 17154300.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[pmid9039502-1] Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (May 1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.

[pmid12459267-2] Spassov DS, Jurecic R (Dec 2002). "Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins". Gene. 299 (1–2): 195–204. doi:10.1016/S0378-1119(02)01060-0. PMID 12459267.

[pmid12511597-3] Moore FL, Jaruzelska J, Fox MS, Urano J, Firpo MT, Turek PJ, Dorfman DM, Pera RA (Jan 2003). "Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-Like proteins". Proc Natl Acad Sci U S A. 100 (2): 538–43. doi:10.1073/pnas.0234478100. PMC 141031. PMID 12511597.

[entrez-4] "Entrez Gene: PUM2 pumilio homolog 2 (Drosophila)".

[5] Campbell ZT, Menichelli E, Friend K, Wu J, Kimble J, Williamson JR, Wickens M (2012). "Identification of a conserved interface between PUF and CPEB proteins". J Biol Chem. 287 (22): 18854–62. doi:10.1074/jbc.M112.352815. PMC 3365739. PMID 22496444.

[6] Ota R, Kotani T, Yamashita M (2011). "Biochemical characterization of Pumilio1 and Pumilio2 in Xenopus oocytes". J Biol Chem. 286 (4): 2853–63. doi:10.1074/jbc.M110.155523. PMC 3024781. PMID 21098481.

[7] Haston KM, Tung JY, Reijo Pera RA (2009). "Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro". PLOS ONE. 4 (5): e5654. doi:10.1371/journal.pone.0005654. PMC 2681483. PMID 19468308.

[8] Geyer CB, Saba R, Kato Y, Anderson AJ, Chappell VK, Saga Y, Eddy EM (2012). "Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male". Biol Reprod. 86 (4): 127. doi:10.1095/biolreprod.111.094938. PMC 3338663. PMID 22190708.

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@@ Line 1: / Line 1: @@
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+{{Underlinked|date=March 2014}}
-{{PBB_Controls
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+{{Infobox_gene}}
-{{GNF_Protein_box
+'''Pumilio homolog 2''' is an [[RNA-binding protein]] that in humans is encoded by the ''PUM2'' [[gene]].<ref name="pmid9039502">{{cite journal | vauthors = Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N | title = Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain | journal = DNA Res | volume = 3 | issue = 5 | pages = 321–9, 341–54 | date = May 1997 | pmid = 9039502 | pmc =  | doi = 10.1093/dnares/3.5.321 }}</ref><ref name="pmid12459267">{{cite journal | vauthors = Spassov DS, Jurecic R | title = Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins | journal = Gene | volume = 299 | issue = 1–2 | pages = 195–204 | date = Dec 2002 | pmid = 12459267 | pmc =  | doi = 10.1016/S0378-1119(02)01060-0 }}</ref><ref name="pmid12511597">{{cite journal | vauthors = Moore FL, Jaruzelska J, Fox MS, Urano J, Firpo MT, Turek PJ, Dorfman DM, Pera RA | title = Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-Like proteins | journal = Proc Natl Acad Sci U S A | volume = 100 | issue = 2 | pages = 538–43 | date = Jan 2003 | pmid = 12511597 | pmc = 141031 | doi = 10.1073/pnas.0234478100 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PUM2 pumilio homolog 2 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23369| accessdate = }}</ref>
- | image = PBB_Protein_PUM2_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1ib2.
- | PDB = {{PDB2|1ib2}}, {{PDB2|1m8w}}, {{PDB2|1m8x}}, {{PDB2|1m8y}}, {{PDB2|1m8z}}
- | Name = Pumilio homolog 2 (Drosophila)
- | HGNCid = 14958
- | Symbol = PUM2
- | AltSymbols =; FLJ36528; KIAA0235; MGC138251; MGC138253; PUMH2; PUML2
- | OMIM = 607205
- | ECnumber =
- | Homologene = 69183
- | MGIid = 1931751
-  | GeneAtlas_image1 = PBB_GE_PUM2_201493_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_PUM2_216221_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
- | Component =
- | Process = {{GNF_GO|id=GO:0006417 |text = regulation of translation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 23369
-    | Hs_Ensembl = ENSG00000055917
-    | Hs_RefseqProtein = NP_056132
-    | Hs_RefseqmRNA = NM_015317
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 2
-    | Hs_GenLoc_start = 20311933
-    | Hs_GenLoc_end = 20413944
-    | Hs_Uniprot = Q8TB72
-    | Mm_EntrezGene = 80913
-    | Mm_Ensembl = ENSMUSG00000020594
-    | Mm_RefseqmRNA = XM_978653
-    | Mm_RefseqProtein = XP_983747
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 12
-    | Mm_GenLoc_start = 8700689
-    | Mm_GenLoc_end = 8776347
-    | Mm_Uniprot = Q3TTH9
-  }}
-}}
-'''Pumilio homolog 2 (Drosophila)''', also known as '''PUM2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PUM2 pumilio homolog 2 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23369| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+==Interactions==
-{{PBB_Summary
+BRCA1 has been shown to [[Protein-protein interaction|interact]] with the following proteins:
-| section_title =
+* [[CPEB]]<ref>{{cite journal | vauthors = Campbell ZT, Menichelli E, Friend K, Wu J, Kimble J, Williamson JR, Wickens M | title = Identification of a conserved interface between PUF and CPEB proteins. | journal = J Biol Chem | volume = 287 | issue = 22 | pages = 18854–62 | year = 2012 | pmid = 22496444 | doi = 10.1074/jbc.M112.352815 | pmc=3365739}}</ref>
-| summary_text =
+* [[DAZL]]<ref>{{cite journal | vauthors = Ota R, Kotani T, Yamashita M | title = Biochemical characterization of Pumilio1 and Pumilio2 in Xenopus oocytes. | journal = J Biol Chem | volume = 286 | issue = 4 | pages = 2853–63 | year = 2011 | pmid = 21098481 | doi = 10.1074/jbc.M110.155523 | pmc=3024781}}</ref>
-}}
+* [[DAZ1]]<ref>{{cite journal | vauthors = Haston KM, Tung JY, Reijo Pera RA | title = Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro. | journal = PLOS ONE | volume = 4 | issue = 5 | pages = e5654 | year = 2009 | pmid = 19468308 | doi = 10.1371/journal.pone.0005654 | pmc=2681483}}</ref>
+* [[NANOS1]]<ref>{{cite journal | vauthors = Geyer CB, Saba R, Kato Y, Anderson AJ, Chappell VK, Saga Y, Eddy EM | title = Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male. | journal = Biol Reprod | volume = 86 | issue = 4 | pages = 127 | year = 2012 | pmid = 22190708 | doi = 10.1095/biolreprod.111.094938 | pmc=3338663}}</ref>
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
-{{PBB_Further_reading
+*{{cite journal | vauthors = Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T | title = Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones | journal = DNA Res. | volume = 9 | issue = 3 | pages = 99–106 | year = 2003 | pmid = 12168954 | doi = 10.1093/dnares/9.3.99 }}
-| citations =
+*{{cite journal | vauthors = Spik A, Oczkowski S, Olszak A, Kotecki M, Formanowicz P, Błazewicz J, Jaruzelska J | title = Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line | journal = Reproductive biology | volume = 6 Suppl 1 | issue =  | pages = 37–42 | year = 2006 | pmid = 16967088 | doi =  }}
-*{{cite journal  | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99-106 |year= 2003 |pmid= 12168954 |doi=  }}
+*{{cite journal | vauthors = Nakayama M, Kikuno R, Ohara O | title = Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs | journal = Genome Res. | volume = 12 | issue = 11 | pages = 1773–84 | year = 2003 | pmid = 12421765 | pmc = 187542 | doi = 10.1101/gr.406902 }}
-*{{cite journal  | author=Spik A, Oczkowski S, Olszak A, ''et al.'' |title=Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line. |journal=Reproductive biology |volume=6 Suppl 1 |issue=  |pages= 37-42 |year= 2006 |pmid= 16967088 |doi=  }}
+*{{cite journal | vauthors = Jaruzelska J, Kotecki M, Kusz K, Spik A, Firpo M, Reijo Pera RA | title = Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells | journal = Dev. Genes Evol. | volume = 213 | issue = 3 | pages = 120–6 | year = 2004 | pmid = 12690449 | doi = 10.1007/s00427-003-0303-2 }}
-*{{cite journal  | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321-9, 341-54 |year= 1997 |pmid= 9039502 |doi=  }}
+*{{cite journal | vauthors = Dazard JE, Gal H, Amariglio N, Rechavi G, Domany E, Givol D | title = Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer | journal = Oncogene | volume = 22 | issue = 19 | pages = 2993–3006 | year = 2003 | pmid = 12771951 | doi = 10.1038/sj.onc.1206537 }}
-*{{cite journal  | author=Nakayama M, Kikuno R, Ohara O |title=Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. |journal=Genome Res. |volume=12 |issue= 11 |pages= 1773-84 |year= 2003 |pmid= 12421765 |doi= 10.1101/gr.406902 }}
+*{{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 33 | pages = 12130–5 | year = 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Spassov DS, Jurecic R |title=Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins. |journal=Gene |volume=299 |issue= 1-2 |pages= 195-204 |year= 2003 |pmid= 12459267 |doi=  }}
+*{{cite journal | vauthors = Fox M, Urano J, Reijo Pera RA | title = Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind | journal = Genomics | volume = 85 | issue = 1 | pages = 92–105 | year = 2005 | pmid = 15607425 | doi = 10.1016/j.ygeno.2004.10.003 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal | vauthors = Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW | title = P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA | journal = J. Cell. Physiol. | volume = 204 | issue = 1 | pages = 99–105 | year = 2005 | pmid = 15617101 | doi = 10.1002/jcp.20263 }}
-*{{cite journal  | author=Moore FL, Jaruzelska J, Fox MS, ''et al.'' |title=Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 2 |pages= 538-43 |year= 2003 |pmid= 12511597 |doi= 10.1073/pnas.0234478100 }}
+*{{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
-*{{cite journal  | author=Jaruzelska J, Kotecki M, Kusz K, ''et al.'' |title=Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells. |journal=Dev. Genes Evol. |volume=213 |issue= 3 |pages= 120-6 |year= 2004 |pmid= 12690449 |doi= 10.1007/s00427-003-0303-2 }}
+*{{cite journal | vauthors = Kusz K, Ginter-Matuszewska B, Ziolkowska K, Spik A, Bierla J, Jedrzejczak P, Latos-Bielenska A, Pawelczyk L, Jaruzelska J | title = Polymorphisms of the human PUMILIO2 gene and male sterility | journal = Mol. Reprod. Dev. | volume = 74 | issue = 6 | pages = 795–9 | year = 2007 | pmid = 17154300 | doi = 10.1002/mrd.20683 }}
-*{{cite journal  | author=Dazard JE, Gal H, Amariglio N, ''et al.'' |title=Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer. |journal=Oncogene |volume=22 |issue= 19 |pages= 2993-3006 |year= 2003 |pmid= 12771951 |doi= 10.1038/sj.onc.1206537 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Fox M, Urano J, Reijo Pera RA |title=Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind. |journal=Genomics |volume=85 |issue= 1 |pages= 92-105 |year= 2005 |pmid= 15607425 |doi= 10.1016/j.ygeno.2004.10.003 }}
-*{{cite journal  | author=Scott RE, White-Grindley E, Ruley HE, ''et al.'' |title=P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA. |journal=J. Cell. Physiol. |volume=204 |issue= 1 |pages= 99-105 |year= 2005 |pmid= 15617101 |doi= 10.1002/jcp.20263 }}
-*{{cite journal  | author=Hillier LW, Graves TA, Fulton RS, ''et al.'' |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
-*{{cite journal  | author=Kusz K, Ginter-Matuszewska B, Ziolkowska K, ''et al.'' |title=Polymorphisms of the human PUMILIO2 gene and male sterility. |journal=Mol. Reprod. Dev. |volume=74 |issue= 6 |pages= 795-9 |year= 2007 |pmid= 17154300 |doi= 10.1002/mrd.20683 }}
-}}
 {{refend}}
-{{protein-stub}}
+{{PDB Gallery|geneid=23369}}
-{{WikiDoc Sources}}
+{{gene-2-stub}}

PUM2: Difference between revisions

Latest revision as of 19:00, 7 September 2017

Interactions

References

Further reading

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