TLX1: Difference between revisions

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Latest revision as of 15:38, 8 November 2017

T-cell leukemia homeobox protein 1 is a protein that in humans is encoded by the TLX1 gene, which was initially named HOX11.^[1]^[2]^[3]^[4]^[5]

Interactions

TLX1 has been shown to interact with PPP1CC,^[6] PPP2CB^[6] and PPP2CA.^[6]

References

↑ Hatano M, Roberts CW, Minden M, Crist WM, Korsmeyer SJ (Jul 1991). "Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia". Science. 253 (5015): 79–82. doi:10.1126/science.1676542. PMID 1676542.
↑ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
↑ "Entrez Gene: TLX1 T-cell leukemia homeobox 1".
↑ Kennedy MA, Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH (Oct 1991). "HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24". Proceedings of the National Academy of Sciences of the United States of America. 88 (20): 8900–4. doi:10.1073/pnas.88.20.8900. PMC 52618. PMID 1681546.
↑ Dubé ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J (Dec 1991). "A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14)". Blood. 78 (11): 2996–3003. PMID 1683261.
↑ ^6.0 ^6.1 ^6.2 Kawabe T, Muslin AJ, Korsmeyer SJ (Jan 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. doi:10.1038/385454a0. PMID 9009195.

Allen TD, Zhu YX, Hawley TS, Hawley RG (Oct 2000). "TALE homeoproteins as HOX11-interacting partners in T-cell leukemia". Leukemia & Lymphoma. 39 (3–4): 241–56. doi:10.3109/10428190009065824. PMID 11342305.
Lu M, Zhang N, Ho AD (Jul 1992). "Genomic organization of the putative human homeobox proto-oncogene HOX-11 (TCL-3) and its endogenous expression in T cells". Oncogene. 7 (7): 1325–30. PMID 1352396.
Kennedy MA, Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH (Oct 1991). "HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24". Proceedings of the National Academy of Sciences of the United States of America. 88 (20): 8900–4. doi:10.1073/pnas.88.20.8900. PMC 52618. PMID 1681546.
Lu M, Gong ZY, Shen WF, Ho AD (Oct 1991). "The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein". The EMBO Journal. 10 (10): 2905–10. PMC 453003. PMID 1717256.
Dear TN, Colledge WH, Carlton MB, Lavenir I, Larson T, Smith AJ, Warren AJ, Evans MJ, Sofroniew MV, Rabbitts TH (Sep 1995). "The Hox11 gene is essential for cell survival during spleen development". Development. 121 (9): 2909–15. PMID 7555717.
Dear TN, Sanchez-Garcia I, Rabbitts TH (May 1993). "The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes". Proceedings of the National Academy of Sciences of the United States of America. 90 (10): 4431–5. doi:10.1073/pnas.90.10.4431. PMC 46525. PMID 8099440.
Kawabe T, Muslin AJ, Korsmeyer SJ (Jan 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. doi:10.1038/385454a0. PMID 9009195.
Brake RL, Kees UR, Watt PM (Oct 1998). "Multiple negative elements contribute to repression of the HOX11 proto-oncogene". Oncogene. 17 (14): 1787–95. doi:10.1038/sj.onc.1202078. PMID 9778044.
Zhang N, Shen W, Hawley RG, Lu M (Apr 1999). "HOX11 interacts with CTF1 and mediates hematopoietic precursor cell immortalization". Oncogene. 18 (13): 2273–9. doi:10.1038/sj.onc.1202545. PMID 10327073.
Watt PM, Ranford PR, Kees UR (Jun 1999). "Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line". Gene. 234 (1): 169–76. doi:10.1016/S0378-1119(99)00157-2. PMID 10393251.
Brake RL, Kees UR, Watt PM (May 2002). "A complex containing PBX2 contributes to activation of the proto-oncogene HOX11". Biochemical and Biophysical Research Communications. 294 (1): 23–34. doi:10.1016/S0006-291X(02)00426-6. PMID 12054735.
Bodenmiller DM, Baxter CS, Hansen DV, Potter SS (Apr 2002). "Phylogenetic analysis of Hoxa 11 sequences reveals absence of transposable elements, conservation of transcription factor binding sites, and suggests antisense coding function". DNA Sequence. 13 (2): 77–83. doi:10.1080/10425170290029981. PMID 12180349.
Cavé H, Suciu S, Preudhomme C, Poppe B, Robert A, Uyttebroeck A, Malet M, Boutard P, Benoit Y, Mauvieux L, Lutz P, Méchinaud F, Grardel N, Mazingue F, Dupont M, Margueritte G, Pages MP, Bertrand Y, Plouvier E, Brunie G, Bastard C, Plantaz D, Vande Velde I, Hagemeijer A, Speleman F, Lessard M, Otten J, Vilmer E, Dastugue N (Jan 2004). "Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951". Blood. 103 (2): 442–50. doi:10.1182/blood-2003-05-1495. PMID 14504110.
Hoffmann K, Dixon DN, Greene WK, Ford J, Taplin R, Kees UR (Dec 2004). "A microarray model system identifies potential new target genes of the proto-oncogene HOX11". Genes, Chromosomes & Cancer. 41 (4): 309–20. doi:10.1002/gcc.20104. PMID 15384172.
Riz I, Hawley RG (Aug 2005). "G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia". Oncogene. 24 (36): 5561–75. doi:10.1038/sj.onc.1208727. PMC 2408753. PMID 15897879.
Heidari M, Rice KL, Phillips JK, Kees UR, Greene WK (Feb 2006). "The nuclear oncoprotein TLX1/HOX11 associates with pericentromeric satellite 2 DNA in leukemic T-cells". Leukemia. 20 (2): 304–12. doi:10.1038/sj.leu.2404071. PMID 16357834.
Chen E, Lim MS, Rosic-Kablar S, Liu J, Jolicoeur P, Dubé ID, Hough MR (Apr 2006). "Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic mice". Oncogene. 25 (18): 2575–87. doi:10.1038/sj.onc.1209285. PMID 16407851.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

[pmid1676542-1] Hatano M, Roberts CW, Minden M, Crist WM, Korsmeyer SJ (Jul 1991). "Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia". Science. 253 (5015): 79–82. doi:10.1126/science.1676542. PMID 1676542.

[pmid1973146-2] McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[entrez-3] "Entrez Gene: TLX1 T-cell leukemia homeobox 1".

[4] Kennedy MA, Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH (Oct 1991). "HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24". Proceedings of the National Academy of Sciences of the United States of America. 88 (20): 8900–4. doi:10.1073/pnas.88.20.8900. PMC 52618. PMID 1681546.

[5] Dubé ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J (Dec 1991). "A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14)". Blood. 78 (11): 2996–3003. PMID 1683261.

[pmid9009195-6] 6.0 ^6.1 ^6.2 Kawabe T, Muslin AJ, Korsmeyer SJ (Jan 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. doi:10.1038/385454a0. PMID 9009195.

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@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{lead too short|date=November 2017}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''T-cell leukemia homeobox protein 1''' is a [[protein]] that in humans is encoded by the ''TLX1'' [[gene]], which was initially named ''HOX11''.<ref name="pmid1676542">{{cite journal | vauthors = Hatano M, Roberts CW, Minden M, Crist WM, Korsmeyer SJ | title = Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia | journal = Science | volume = 253 | issue = 5015 | pages = 79–82 | date = Jul 1991 | pmid = 1676542 | pmc =  | doi = 10.1126/science.1676542 }}</ref><ref name="pmid1973146">{{cite journal | vauthors = McAlpine PJ, Shows TB | title = Nomenclature for human homeobox genes | journal = Genomics | volume = 7 | issue = 3 | pages = 460 | date = Jul 1990 | pmid = 1973146 | pmc =  | doi = 10.1016/0888-7543(90)90186-X }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TLX1 T-cell leukemia homeobox 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3195| accessdate = }}</ref><ref>{{cite journal | vauthors = Kennedy MA, Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH | title = HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 88 | issue = 20 | pages = 8900–4 | date = Oct 1991 | pmc = 52618 | pmid = 1681546 | doi=10.1073/pnas.88.20.8900}}</ref><ref>{{cite journal | vauthors = Dubé ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J | title = A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14) | journal = Blood | volume = 78 | issue = 11 | pages = 2996–3003 | date = Dec 1991 | pmid = 1683261}}</ref>
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = T-cell leukemia homeobox 1
- | HGNCid = 5056
- | Symbol = TLX1
- | AltSymbols =; HOX11; MGC163402; TCL3
- | OMIM = 186770
- | ECnumber =
- | Homologene = 4031
- | MGIid = 98769
- | GeneAtlas_image1 = PBB_GE_TLX1_207179_at_tn.png
- | Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}} {{GNF_GO|id=GO:0046982 |text = protein heterodimerization activity}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007417 |text = central nervous system development}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}} {{GNF_GO|id=GO:0030182 |text = neuron differentiation}} {{GNF_GO|id=GO:0045165 |text = cell fate commitment}} {{GNF_GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0048536 |text = spleen development}} {{GNF_GO|id=GO:0048645 |text = organ formation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 3195
-    | Hs_Ensembl = ENSG00000107807
-    | Hs_RefseqProtein = NP_005512
-    | Hs_RefseqmRNA = NM_005521
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 10
-    | Hs_GenLoc_start = 102880252
-    | Hs_GenLoc_end = 102887536
-    | Hs_Uniprot = P31314
-    | Mm_EntrezGene = 21908
-    | Mm_Ensembl = ENSMUSG00000025215
-    | Mm_RefseqmRNA = NM_021901
-    | Mm_RefseqProtein = NP_068701
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 19
-    | Mm_GenLoc_start = 45204026
-    | Mm_GenLoc_end = 45210254
-    | Mm_Uniprot = Q9QX99
-  }}
-}}
-'''T-cell leukemia homeobox 1''', also known as '''TLX1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TLX1 T-cell leukemia homeobox 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3195| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+TLX1 has been shown to [[Protein-protein interaction|interact]] with [[PPP1CC]],<ref name=pmid9009195>{{cite journal | vauthors = Kawabe T, Muslin AJ, Korsmeyer SJ | title = HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint | journal = Nature | volume = 385 | issue = 6615 | pages = 454–8 | date = Jan 1997 | pmid = 9009195 | doi = 10.1038/385454a0 }}</ref> [[PPP2CB]]<ref name=pmid9009195/> and [[PPP2CA]].<ref name=pmid9009195/>
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+{{clear}}
-{{refbegin | 2}}
-{{PBB_Further_reading
+== Further reading ==
-| citations =
+{{refbegin |33em}}
-*{{cite journal  | author=Allen TD, Zhu YX, Hawley TS, Hawley RG |title=TALE homeoproteins as HOX11-interacting partners in T-cell leukemia. |journal=Leuk. Lymphoma |volume=39 |issue= 3-4 |pages= 241-56 |year= 2001 |pmid= 11342305 |doi=  }}
+* {{cite journal | vauthors = Allen TD, Zhu YX, Hawley TS, Hawley RG | title = TALE homeoproteins as HOX11-interacting partners in T-cell leukemia | journal = Leukemia & Lymphoma | volume = 39 | issue = 3-4 | pages = 241–56 | date = Oct 2000 | pmid = 11342305 | doi = 10.3109/10428190009065824 }}
-*{{cite journal  | author=Lu M, Zhang N, Ho AD |title=Genomic organization of the putative human homeobox proto-oncogene HOX-11 (TCL-3) and its endogenous expression in T cells. |journal=Oncogene |volume=7 |issue= 7 |pages= 1325-30 |year= 1992 |pmid= 1352396 |doi=  }}
+* {{cite journal | vauthors = Lu M, Zhang N, Ho AD | title = Genomic organization of the putative human homeobox proto-oncogene HOX-11 (TCL-3) and its endogenous expression in T cells | journal = Oncogene | volume = 7 | issue = 7 | pages = 1325–30 | date = Jul 1992 | pmid = 1352396 | doi =  }}
-*{{cite journal  | author=Hatano M, Roberts CW, Minden M, ''et al.'' |title=Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. |journal=Science |volume=253 |issue= 5015 |pages= 79-82 |year= 1991 |pmid= 1676542 |doi=  }}
+* {{cite journal | vauthors = Kennedy MA, Gonzalez-Sarmiento R, Kees UR, Lampert F, Dear N, Boehm T, Rabbitts TH | title = HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 88 | issue = 20 | pages = 8900–4 | date = Oct 1991 | pmid = 1681546 | pmc = 52618 | doi = 10.1073/pnas.88.20.8900 }}
-*{{cite journal  | author=Kennedy MA, Gonzalez-Sarmiento R, Kees UR, ''et al.'' |title=HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 20 |pages= 8900-4 |year= 1991 |pmid= 1681546 |doi=  }}
+* {{cite journal | vauthors = Lu M, Gong ZY, Shen WF, Ho AD | title = The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein | journal = The EMBO Journal | volume = 10 | issue = 10 | pages = 2905–10 | date = Oct 1991 | pmid = 1717256 | pmc = 453003 | doi =  }}
-*{{cite journal  | author=Lu M, Gong ZY, Shen WF, Ho AD |title=The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein. |journal=EMBO J. |volume=10 |issue= 10 |pages= 2905-10 |year= 1991 |pmid= 1717256 |doi=  }}
+* {{cite journal | vauthors = Dear TN, Colledge WH, Carlton MB, Lavenir I, Larson T, Smith AJ, Warren AJ, Evans MJ, Sofroniew MV, Rabbitts TH | title = The Hox11 gene is essential for cell survival during spleen development | journal = Development | volume = 121 | issue = 9 | pages = 2909–15 | date = Sep 1995 | pmid = 7555717 | doi =  }}
-*{{cite journal  | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=  }}
+* {{cite journal | vauthors = Dear TN, Sanchez-Garcia I, Rabbitts TH | title = The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 90 | issue = 10 | pages = 4431–5 | date = May 1993 | pmid = 8099440 | pmc = 46525 | doi = 10.1073/pnas.90.10.4431 }}
-*{{cite journal  | author=Dear TN, Colledge WH, Carlton MB, ''et al.'' |title=The Hox11 gene is essential for cell survival during spleen development. |journal=Development |volume=121 |issue= 9 |pages= 2909-15 |year= 1995 |pmid= 7555717 |doi=  }}
+* {{cite journal | vauthors = Kawabe T, Muslin AJ, Korsmeyer SJ | title = HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint | journal = Nature | volume = 385 | issue = 6615 | pages = 454–8 | date = Jan 1997 | pmid = 9009195 | doi = 10.1038/385454a0 }}
-*{{cite journal  | author=Dear TN, Sanchez-Garcia I, Rabbitts TH |title=The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 10 |pages= 4431-5 |year= 1993 |pmid= 8099440 |doi=  }}
+* {{cite journal | vauthors = Brake RL, Kees UR, Watt PM | title = Multiple negative elements contribute to repression of the HOX11 proto-oncogene | journal = Oncogene | volume = 17 | issue = 14 | pages = 1787–95 | date = Oct 1998 | pmid = 9778044 | doi = 10.1038/sj.onc.1202078 }}
-*{{cite journal  | author=Kawabe T, Muslin AJ, Korsmeyer SJ |title=HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint. |journal=Nature |volume=385 |issue= 6615 |pages= 454-8 |year= 1997 |pmid= 9009195 |doi= 10.1038/385454a0 }}
+* {{cite journal | vauthors = Zhang N, Shen W, Hawley RG, Lu M | title = HOX11 interacts with CTF1 and mediates hematopoietic precursor cell immortalization | journal = Oncogene | volume = 18 | issue = 13 | pages = 2273–9 | date = Apr 1999 | pmid = 10327073 | doi = 10.1038/sj.onc.1202545 }}
-*{{cite journal  | author=Brake RL, Kees UR, Watt PM |title=Multiple negative elements contribute to repression of the HOX11 proto-oncogene. |journal=Oncogene |volume=17 |issue= 14 |pages= 1787-95 |year= 1998 |pmid= 9778044 |doi= 10.1038/sj.onc.1202078 }}
+* {{cite journal | vauthors = Watt PM, Ranford PR, Kees UR | title = Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line | journal = Gene | volume = 234 | issue = 1 | pages = 169–76 | date = Jun 1999 | pmid = 10393251 | doi = 10.1016/S0378-1119(99)00157-2 }}
-*{{cite journal  | author=Zhang N, Shen W, Hawley RG, Lu M |title=HOX11 interacts with CTF1 and mediates hematopoietic precursor cell immortalization. |journal=Oncogene |volume=18 |issue= 13 |pages= 2273-9 |year= 1999 |pmid= 10327073 |doi= 10.1038/sj.onc.1202545 }}
+* {{cite journal | vauthors = Brake RL, Kees UR, Watt PM | title = A complex containing PBX2 contributes to activation of the proto-oncogene HOX11 | journal = Biochemical and Biophysical Research Communications | volume = 294 | issue = 1 | pages = 23–34 | date = May 2002 | pmid = 12054735 | doi = 10.1016/S0006-291X(02)00426-6 }}
-*{{cite journal  | author=Watt PM, Ranford PR, Kees UR |title=Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line. |journal=Gene |volume=234 |issue= 1 |pages= 169-76 |year= 1999 |pmid= 10393251 |doi=  }}
+* {{cite journal | vauthors = Bodenmiller DM, Baxter CS, Hansen DV, Potter SS | title = Phylogenetic analysis of Hoxa 11 sequences reveals absence of transposable elements, conservation of transcription factor binding sites, and suggests antisense coding function | journal = DNA Sequence | volume = 13 | issue = 2 | pages = 77–83 | date = Apr 2002 | pmid = 12180349 | doi = 10.1080/10425170290029981 }}
-*{{cite journal  | author=Brake RL, Kees UR, Watt PM |title=A complex containing PBX2 contributes to activation of the proto-oncogene HOX11. |journal=Biochem. Biophys. Res. Commun. |volume=294 |issue= 1 |pages= 23-34 |year= 2002 |pmid= 12054735 |doi= 10.1016/S0006-291X(02)00426-6 }}
+* {{cite journal | vauthors = Cavé H, Suciu S, Preudhomme C, Poppe B, Robert A, Uyttebroeck A, Malet M, Boutard P, Benoit Y, Mauvieux L, Lutz P, Méchinaud F, Grardel N, Mazingue F, Dupont M, Margueritte G, Pages MP, Bertrand Y, Plouvier E, Brunie G, Bastard C, Plantaz D, Vande Velde I, Hagemeijer A, Speleman F, Lessard M, Otten J, Vilmer E, Dastugue N | title = Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951 | journal = Blood | volume = 103 | issue = 2 | pages = 442–50 | date = Jan 2004 | pmid = 14504110 | doi = 10.1182/blood-2003-05-1495 }}
-*{{cite journal  | author=Bodenmiller DM, Baxter CS, Hansen DV, Potter SS |title=Phylogenetic analysis of Hoxa 11 sequences reveals absence of transposable elements, conservation of transcription factor binding sites, and suggests antisense coding function. |journal=DNA Seq. |volume=13 |issue= 2 |pages= 77-83 |year= 2003 |pmid= 12180349 |doi=  }}
+* {{cite journal | vauthors = Hoffmann K, Dixon DN, Greene WK, Ford J, Taplin R, Kees UR | title = A microarray model system identifies potential new target genes of the proto-oncogene HOX11 | journal = Genes, Chromosomes & Cancer | volume = 41 | issue = 4 | pages = 309–20 | date = Dec 2004 | pmid = 15384172 | doi = 10.1002/gcc.20104 }}
-*{{cite journal  | author=Cavé H, Suciu S, Preudhomme C, ''et al.'' |title=Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951. |journal=Blood |volume=103 |issue= 2 |pages= 442-50 |year= 2004 |pmid= 14504110 |doi= 10.1182/blood-2003-05-1495 }}
+* {{cite journal | vauthors = Riz I, Hawley RG | title = G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia | journal = Oncogene | volume = 24 | issue = 36 | pages = 5561–75 | date = Aug 2005 | pmid = 15897879 | pmc = 2408753 | doi = 10.1038/sj.onc.1208727 }}
-*{{cite journal  | author=Hoffmann K, Dixon DN, Greene WK, ''et al.'' |title=A microarray model system identifies potential new target genes of the proto-oncogene HOX11. |journal=Genes Chromosomes Cancer |volume=41 |issue= 4 |pages= 309-20 |year= 2005 |pmid= 15384172 |doi= 10.1002/gcc.20104 }}
+* {{cite journal | vauthors = Heidari M, Rice KL, Phillips JK, Kees UR, Greene WK | title = The nuclear oncoprotein TLX1/HOX11 associates with pericentromeric satellite 2 DNA in leukemic T-cells | journal = Leukemia | volume = 20 | issue = 2 | pages = 304–12 | date = Feb 2006 | pmid = 16357834 | doi = 10.1038/sj.leu.2404071 }}
-*{{cite journal  | author=Riz I, Hawley RG |title=G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia. |journal=Oncogene |volume=24 |issue= 36 |pages= 5561-75 |year= 2005 |pmid= 15897879 |doi= 10.1038/sj.onc.1208727 }}
+* {{cite journal | vauthors = Chen E, Lim MS, Rosic-Kablar S, Liu J, Jolicoeur P, Dubé ID, Hough MR | title = Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic mice | journal = Oncogene | volume = 25 | issue = 18 | pages = 2575–87 | date = Apr 2006 | pmid = 16407851 | doi = 10.1038/sj.onc.1209285 }}
-*{{cite journal  | author=Heidari M, Rice KL, Phillips JK, ''et al.'' |title=The nuclear oncoprotein TLX1/HOX11 associates with pericentromeric satellite 2 DNA in leukemic T-cells. |journal=Leukemia |volume=20 |issue= 2 |pages= 304-12 |year= 2006 |pmid= 16357834 |doi= 10.1038/sj.leu.2404071 }}
-*{{cite journal  | author=Chen E, Lim MS, Rosic-Kablar S, ''et al.'' |title=Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic mice. |journal=Oncogene |volume=25 |issue= 18 |pages= 2575-87 |year= 2006 |pmid= 16407851 |doi= 10.1038/sj.onc.1209285 }}
-}}
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-{{WikiDoc Sources}}
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TLX1: Difference between revisions

Latest revision as of 15:38, 8 November 2017

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