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{{Infobox_gene}}
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'''Interferon-induced protein with tetratricopeptide repeats 1''' is a [[protein]] that in humans is encoded by the ''IFIT1'' [[gene]].<ref name="pmid1377167">{{cite journal |vauthors=Lafage M, Clauss I, Couez D, Simonetti J, Wathelet MG, Huez G | title = The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24 | journal = Genomics | volume = 13 | issue = 2 | pages = 458–60 |date=Jul 1992 | pmid = 1377167 | pmc = | doi =10.1016/0888-7543(92)90272-T }}</ref><ref name="pmid3360121">{{cite journal |vauthors=Wathelet MG, Clauss IM, Content J, Huez GA | title = The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family | journal = FEBS Lett | volume = 231 | issue = 1 | pages = 164–71 |date=Jun 1988 | pmid = 3360121 | pmc =  | doi =10.1016/0014-5793(88)80724-5 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFIT1 interferon-induced protein with tetratricopeptide repeats 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3434| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Interferon-induced protein with tetratricopeptide repeats 1
| HGNCid = 5407
| Symbol = IFIT1
| AltSymbols =; G10P1; GARG-16; IFI-56; IFI56; IFNAI1; ISG56; RNM561
| OMIM = 147690
| ECnumber =
| Homologene = 78213
| MGIid = 2148249
| GeneAtlas_image1 = PBB_GE_IFIT1_203153_at_tn.png
| Function = {{GNF_GO|id=GO:0005488 |text = binding}}
  | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}}  
| Process = {{GNF_GO|id=GO:0006955 |text = immune response}} {{GNF_GO|id=GO:0008150 |text = biological_process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3434
    | Hs_Ensembl = ENSG00000185745
    | Hs_RefseqProtein = NP_001001887
    | Hs_RefseqmRNA = NM_001001887
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 91142283
    | Hs_GenLoc_end = 91153725
    | Hs_Uniprot = P09914
    | Mm_EntrezGene = 112419
    | Mm_Ensembl = ENSMUSG00000067297
    | Mm_RefseqmRNA = NM_053217
    | Mm_RefseqProtein = NP_444447
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 19
    | Mm_GenLoc_start = 34683048
    | Mm_GenLoc_end = 34706740
    | Mm_Uniprot =  
  }}
}}
'''Interferon-induced protein with tetratricopeptide repeats 1''', also known as '''IFIT1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: IFIT1 interferon-induced protein with tetratricopeptide repeats 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3434| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Lafage M, Clauss I, Couez D, ''et al.'' |title=The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24. |journal=Genomics |volume=13 |issue= 2 |pages= 458-60 |year= 1992 |pmid= 1377167 |doi=  }}
*{{cite journal   |vauthors=Wathelet MG, Clauss IM, Nols CB, etal |title=New inducers revealed by the promoter sequence analysis of two interferon-activated human genes. |journal=Eur. J. Biochem. |volume=169 |issue= 2 |pages= 313–21 |year= 1988 |pmid= 3121313 |doi=10.1111/j.1432-1033.1987.tb13614.x }}
*{{cite journal  | author=Wathelet MG, Clauss IM, Nols CB, ''et al.'' |title=New inducers revealed by the promoter sequence analysis of two interferon-activated human genes. |journal=Eur. J. Biochem. |volume=169 |issue= 2 |pages= 313-21 |year= 1988 |pmid= 3121313 |doi=  }}
*{{cite journal   |vauthors=Wathelet MG, Szpirer J, Nols CB, etal |title=Cloning and chromosomal location of human genes inducible by type I interferon. |journal=Somat. Cell Mol. Genet. |volume=14 |issue= 5 |pages= 415–26 |year= 1988 |pmid= 3175763 |doi=10.1007/BF01534709 }}
*{{cite journal | author=Wathelet MG, Szpirer J, Nols CB, ''et al.'' |title=Cloning and chromosomal location of human genes inducible by type I interferon. |journal=Somat. Cell Mol. Genet. |volume=14 |issue= 5 |pages= 415-26 |year= 1988 |pmid= 3175763 |doi= }}
*{{cite journal  |vauthors=Kusari J, Szabo P, Grzeschik KH, Sen GC |title=Chromosomal localization of the interferon-inducible human gene encoding mRNA 561. |journal=J. Interferon Res. |volume=7 |issue= 1 |pages= 53–9 |year= 1987 |pmid= 3585080 |doi=10.1089/jir.1987.7.53 }}
*{{cite journal  | author=Wathelet MG, Clauss IM, Content J, Huez GA |title=The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family. |journal=FEBS Lett. |volume=231 |issue= 1 |pages= 164-71 |year= 1988 |pmid= 3360121 |doi= }}
*{{cite journal   |vauthors=Wathelet M, Moutschen S, Defilippi P, etal |title=Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons |journal=Eur. J. Biochem. |volume=155 |issue= 1 |pages= 11–7 |year= 1986 |pmid= 3753936 |doi=10.1111/j.1432-1033.1986.tb09452.x }}
*{{cite journal  | author=Kusari J, Szabo P, Grzeschik KH, Sen GC |title=Chromosomal localization of the interferon-inducible human gene encoding mRNA 561. |journal=J. Interferon Res. |volume=7 |issue= 1 |pages= 53-9 |year= 1987 |pmid= 3585080 |doi=  }}
*{{cite journal   |vauthors=Chebath J, Merlin G, Metz R, etal |title=Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA |journal=Nucleic Acids Res. |volume=11 |issue= 5 |pages= 1213–26 |year= 1983 |pmid= 6186990 |doi=10.1093/nar/11.5.1213  | pmc=325791 }}
*{{cite journal | author=Wathelet M, Moutschen S, Defilippi P, ''et al.'' |title=Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons. |journal=Eur. J. Biochem. |volume=155 |issue= 1 |pages= 11-7 |year= 1986 |pmid= 3753936 |doi=  }}
*{{cite journal  |vauthors=Rebouillat D, Marié I, Hovanessian AG |title=Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase |journal=Eur. J. Biochem. |volume=257 |issue= 2 |pages= 319–30 |year= 1998 |pmid= 9826176 |doi=10.1046/j.1432-1327.1998.2570319.x }}
*{{cite journal | author=Chebath J, Merlin G, Metz R, ''et al.'' |title=Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA. |journal=Nucleic Acids Res. |volume=11 |issue= 5 |pages= 1213-26 |year= 1983 |pmid= 6186990 |doi=  }}
*{{cite journal  |vauthors=Guo J, Sen GC |title=Characterization of the Interaction between the Interferon-Induced Protein P56 and the Int6 Protein Encoded by a Locus of Insertion of the Mouse Mammary Tumor Virus |journal=J. Virol. |volume=74 |issue= 4 |pages= 1892–9 |year= 2000 |pmid= 10644362 |doi=10.1128/JVI.74.4.1892-1899.2000  | pmc=111667 }}
*{{cite journal  | author=Rebouillat D, Marié I, Hovanessian AG |title=Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase. |journal=Eur. J. Biochem. |volume=257 |issue= 2 |pages= 319-30 |year= 1998 |pmid= 9826176 |doi=  }}
*{{cite journal  |vauthors=Guo J, Peters KL, Sen GC |title=Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection |journal=Virology |volume=267 |issue= 2 |pages= 209–19 |year= 2000 |pmid= 10662616 |doi= 10.1006/viro.1999.0135 }}
*{{cite journal  | author=Guo J, Sen GC |title=Characterization of the interaction between the interferon-induced protein P56 and the Int6 protein encoded by a locus of insertion of the mouse mammary tumor virus. |journal=J. Virol. |volume=74 |issue= 4 |pages= 1892-9 |year= 2000 |pmid= 10644362 |doi=  }}
*{{cite journal  |vauthors=Guo J, Hui DJ, Merrick WC, Sen GC |title=A new pathway of translational regulation mediated by eukaryotic initiation factor 3 |journal=EMBO J. |volume=19 |issue= 24 |pages= 6891–9 |year= 2001 |pmid= 11118224 |doi= 10.1093/emboj/19.24.6891 | pmc=305884 }}
*{{cite journal  | author=Guo J, Peters KL, Sen GC |title=Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection. |journal=Virology |volume=267 |issue= 2 |pages= 209-19 |year= 2000 |pmid= 10662616 |doi= 10.1006/viro.1999.0135 }}
*{{cite journal  |vauthors=Patzwahl R, Meier V, Ramadori G, Mihm S |title=Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive Hybridization |journal=J. Virol. |volume=75 |issue= 3 |pages= 1332–8 |year= 2001 |pmid= 11152506 |doi= 10.1128/JVI.75.3.1332-1338.2001 | pmc=114039 }}
*{{cite journal  | author=Guo J, Hui DJ, Merrick WC, Sen GC |title=A new pathway of translational regulation mediated by eukaryotic initiation factor 3. |journal=EMBO J. |volume=19 |issue= 24 |pages= 6891-9 |year= 2001 |pmid= 11118224 |doi= 10.1093/emboj/19.24.6891 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Patzwahl R, Meier V, Ramadori G, Mihm S |title=Enhanced expression of interferon-regulated genes in the liver of patients with chronic hepatitis C virus infection: detection by suppression-subtractive hybridization. |journal=J. Virol. |volume=75 |issue= 3 |pages= 1332-8 |year= 2001 |pmid= 11152506 |doi= 10.1128/JVI.75.3.1332-1338.2001 }}
*{{cite journal   |vauthors=Gavrilov BG, Monastyrskaia GS, Velikodvorskaia TV, etal |title=[Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus] |journal=Bioorg. Khim. |volume=29 |issue= 2 |pages= 175–80 |year= 2003 |pmid= 12708317 |doi=  }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Gavrilov BG, Monastyrskaia GS, Velikodvorskaia TV, ''et al.'' |title=[Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus] |journal=Bioorg. Khim. |volume=29 |issue= 2 |pages= 175-80 |year= 2003 |pmid= 12708317 |doi=  }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  |vauthors=Terenzi F, Hui DJ, Merrick WC, Sen GC |title=Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56 |journal=J. Biol. Chem. |volume=281 |issue= 45 |pages= 34064–71 |year= 2006 |pmid= 16973618 |doi= 10.1074/jbc.M605771200 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal  | author=Terenzi F, Hui DJ, Merrick WC, Sen GC |title=Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56. |journal=J. Biol. Chem. |volume=281 |issue= 45 |pages= 34064-71 |year= 2006 |pmid= 16973618 |doi= 10.1074/jbc.M605771200 }}
}}
}}
{{refend}}
{{refend}}


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{{gene-10-stub}}

Latest revision as of 23:38, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Interferon-induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene.[1][2][3]


References

  1. ↑ Lafage M, Clauss I, Couez D, Simonetti J, Wathelet MG, Huez G (Jul 1992). "The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24". Genomics. 13 (2): 458–60. doi:10.1016/0888-7543(92)90272-T. PMID 1377167.
  2. ↑ Wathelet MG, Clauss IM, Content J, Huez GA (Jun 1988). "The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family". FEBS Lett. 231 (1): 164–71. doi:10.1016/0014-5793(88)80724-5. PMID 3360121.
  3. ↑ "Entrez Gene: IFIT1 interferon-induced protein with tetratricopeptide repeats 1".

Further reading



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