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'''Mitochondrial GTPase 1''' is an [[enzyme]] that in humans is encoded by the ''MTG1'' [[gene]].<ref name="pmid12808030">{{cite journal |vauthors=Barrientos A, Korr D, Barwell KJ, Sjulsen C, Gajewski CD, Manfredi G, Ackerman S, Tzagoloff A | title = MTG1 codes for a conserved protein required for mitochondrial translation | journal = Mol Biol Cell | volume = 14 | issue = 6 | pages = 2292–302 |date=Jun 2003 | pmid = 12808030 | pmc = 194879 | doi = 10.1091/mbc.E02-10-0636 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92170| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Mitochondrial GTPase 1 homolog (S. cerevisiae)
| HGNCid = 32159
| Symbol = MTG1
| AltSymbols =; GTP; GTPBP7; RP11-108K14.2
| OMIM = 
| ECnumber = 
| Homologene = 44527
| MGIid = 2685015
| GeneAtlas_image1 = PBB_GE_MTG1_212767_at_tn.png
| Function = {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}}
| Process =  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 92170
    | Hs_Ensembl = ENSG00000148824
    | Hs_RefseqProtein = NP_612393
    | Hs_RefseqmRNA = NM_138384
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 135057665
    | Hs_GenLoc_end = 135084813
    | Hs_Uniprot = 
    | Mm_EntrezGene = 212508
    | Mm_Ensembl = ENSMUSG00000039018
    | Mm_RefseqmRNA = NM_199301
    | Mm_RefseqProtein = NP_955005
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 139988975
    | Mm_GenLoc_end = 140001935
    | Mm_Uniprot = 
  }}
}}
'''Mitochondrial GTPase 1 homolog (S. cerevisiae)''', also known as '''MTG1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92170| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Horisberger MA |title=Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins. |journal=J. Virol. |volume=66 |issue= 8 |pages= 4705-9 |year= 1992 |pmid= 1629950 |doi=  }}
*{{cite journal  | author=Horisberger MA |title=Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins. |journal=J. Virol. |volume=66 |issue= 8 |pages= 4705–9 |year= 1992 |pmid= 1629950 |doi= | pmc=241296 }}
*{{cite journal  | author=Wilson AL, Sheridan KM, Erdman RA, Maltese WA |title=Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells. |journal=Biochem. J. |volume=318 ( Pt 3) |issue=  |pages= 1007-14 |year= 1996 |pmid= 8836150 |doi=  }}
*{{cite journal  |vauthors=Wilson AL, Sheridan KM, Erdman RA, Maltese WA |title=Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells. |journal=Biochem. J. |volume=318 |issue=  3|pages= 1007–14 |year= 1996 |pmid= 8836150 |doi= 10.1042/bj3181007| pmc=1217717 }}
*{{cite journal | author=Tsai SC, Adamik R, Hong JX, ''et al.'' |title=Effects of arfaptin 1 on guanine nucleotide-dependent activation of phospholipase D and cholera toxin by ADP-ribosylation factor. |journal=J. Biol. Chem. |volume=273 |issue= 33 |pages= 20697-701 |year= 1998 |pmid= 9694811 |doi=  }}
*{{cite journal   |vauthors=Tsai SC, Adamik R, Hong JX, etal |title=Effects of arfaptin 1 on guanine nucleotide-dependent activation of phospholipase D and cholera toxin by ADP-ribosylation factor. |journal=J. Biol. Chem. |volume=273 |issue= 33 |pages= 20697–701 |year= 1998 |pmid= 9694811 |doi=10.1074/jbc.273.33.20697 }}
*{{cite journal | author=Opdam FJ, Echard A, Croes HJ, ''et al.'' |title=The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus. |journal=J. Cell. Sci. |volume=113 ( Pt 15) |issue=  |pages= 2725-35 |year= 2000 |pmid= 10893188 |doi=  }}
*{{cite journal   |vauthors=Opdam FJ, Echard A, Croes HJ, etal |title=The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus. |journal=J. Cell Sci. |volume=113 |issue=  15|pages= 2725–35 |year= 2000 |pmid= 10893188 |doi=  }}
*{{cite journal | author=Gao X, Satoh T, Liao Y, ''et al.'' |title=Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42219-25 |year= 2001 |pmid= 11524421 |doi= 10.1074/jbc.M105760200 }}
*{{cite journal   |vauthors=Gao X, Satoh T, Liao Y, etal |title=Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42219–25 |year= 2001 |pmid= 11524421 |doi= 10.1074/jbc.M105760200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Kuiperij HB, de Rooij J, Rehmann H, ''et al.'' |title=Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. |journal=Biochim. Biophys. Acta |volume=1593 |issue= 2-3 |pages= 141-9 |year= 2003 |pmid= 12581858 |doi=  }}
*{{cite journal   |vauthors=Kuiperij HB, de Rooij J, Rehmann H, etal |title=Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. |journal=Biochim. Biophys. Acta |volume=1593 |issue= 2–3 |pages= 141–9 |year= 2003 |pmid= 12581858 |doi=10.1016/S0167-4889(02)00365-8  }}
*{{cite journal  | author=Barrientos A, Korr D, Barwell KJ, ''et al.'' |title=MTG1 codes for a conserved protein required for mitochondrial translation. |journal=Mol. Biol. Cell |volume=14 |issue= 6 |pages= 2292-302 |year= 2004 |pmid= 12808030 |doi= 10.1091/mbc.E02-10-0636 }}
*{{cite journal   |vauthors=Premzl M, Sangiorgio L, Strumbo B, etal |title=Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein |journal=Gene |volume=314 |issue=  |pages= 89–102 |year= 2003 |pmid= 14527721 |doi=10.1016/S0378-1119(03)00707-8 }}
*{{cite journal | author=Premzl M, Sangiorgio L, Strumbo B, ''et al.'' |title=Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein. |journal=Gene |volume=314 |issue=  |pages= 89-102 |year= 2003 |pmid= 14527721 |doi=  }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Deloukas P, Earthrowl ME, Grafham DV, etal |title=The DNA sequence and comparative analysis of human chromosome 10 |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375-81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal   |vauthors=Premzl M, Gready JE, Jermiin LS, etal |title=Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysis |journal=Mol. Biol. Evol. |volume=21 |issue= 12 |pages= 2210–31 |year= 2005 |pmid= 15342797 |doi= 10.1093/molbev/msh245 }}
*{{cite journal | author=Premzl M, Gready JE, Jermiin LS, ''et al.'' |title=Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysis. |journal=Mol. Biol. Evol. |volume=21 |issue= 12 |pages= 2210-31 |year= 2005 |pmid= 15342797 |doi= 10.1093/molbev/msh245 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 20:20, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Mitochondrial GTPase 1 is an enzyme that in humans is encoded by the MTG1 gene.[1][2]


References

  1. ↑ Barrientos A, Korr D, Barwell KJ, Sjulsen C, Gajewski CD, Manfredi G, Ackerman S, Tzagoloff A (Jun 2003). "MTG1 codes for a conserved protein required for mitochondrial translation". Mol Biol Cell. 14 (6): 2292–302. doi:10.1091/mbc.E02-10-0636. PMC 194879. PMID 12808030.
  2. ↑ "Entrez Gene: MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae)".

Further reading



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