Nucleolar phosphoprotein p130: Difference between revisions

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{{Infobox_gene}}
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'''Nucleolar phosphoprotein p130''' is a [[protein]] that in humans is encoded by the ''NOLC1'' [[gene]].<ref name="pmid7657714">{{cite journal |vauthors=Pai CY, Chen HK, Sheu HL, Yeh NH | title = Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis | series = 108 | journal = J Cell Sci | volume = ( Pt 5) | issue =  | pages = 1911–20 |date=Oct 1995 | pmid = 7657714 | pmc =  | doi =  }}</ref><ref name="pmid10567578">{{cite journal |vauthors=Chen HK, Pai CY, Huang JY, Yeh NH | title = Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structural organization | journal = Mol Cell Biol | volume = 19 | issue = 12 | pages = 8536–46 |date=Jan 2000 | pmid = 10567578 | pmc = 84972 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NOLC1 nucleolar and coiled-body phosphoprotein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9221| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Nucleolar and coiled-body phosphoprotein 1
| HGNCid = 15608
| Symbol = NOLC1
| AltSymbols =; P130; KIAA0035; NOPP130; NOPP140; NS5ATP13
| OMIM = 602394
| ECnumber = 
| Homologene = 68818
| MGIid = 1918019
| GeneAtlas_image1 = PBB_GE_NOLC1_205895_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_NOLC1_211949_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_NOLC1_211951_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005730 |text = nucleolus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
| Process = {{GNF_GO|id=GO:0006364 |text = rRNA processing}} {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0007067 |text = mitosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9221
    | Hs_Ensembl = ENSG00000166197
    | Hs_RefseqProtein = NP_004732
    | Hs_RefseqmRNA = NM_004741
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 103902107
    | Hs_GenLoc_end = 103913617
    | Hs_Uniprot = Q14978
    | Mm_EntrezGene = 70769
    | Mm_Ensembl = ENSMUSG00000015176
    | Mm_RefseqmRNA = NM_001039351
    | Mm_RefseqProtein = NP_001034440
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 19
    | Mm_GenLoc_start = 46129174
    | Mm_GenLoc_end = 46138841
    | Mm_Uniprot = 
  }}
}}
'''Nucleolar and coiled-body phosphoprotein 1''', also known as '''NOLC1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NOLC1 nucleolar and coiled-body phosphoprotein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9221| accessdate = }}</ref>
 
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==Interactions==
Nucleolar phosphoprotein p130 has been shown to [[Protein-protein interaction|interact]] with [[Coilin]]<ref name=pmid9679133>{{cite journal |doi=10.1083/jcb.142.2.319 |last=Isaac |first=C |authorlink= |author2=Yang Y |author3=Meier U T  |date=Jul 1998 |title=Nopp140 functions as a molecular link between the nucleolus and the coiled bodies |journal=J. Cell Biol. |volume=142 |issue=2 |pages=319–29 |publisher= |location = UNITED STATES| issn = 0021-9525| pmid = 9679133 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=2133063 }}</ref> and [[CEBPB]].<ref name=pmid9553145>{{cite journal |doi=10.1074/jbc.273.17.10784 |last=Miau |first=L H |authorlink= |author2=Chang C J |author3=Shen B J |author4=Tsai W H |author5=Lee S C  |date=Apr 1998 |title=Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation |journal=J. Biol. Chem. |volume=273 |issue=17 |pages=10784–91 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9553145 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27-35 |year= 1995 |pmid= 7584026 |doi=  }}
*{{cite journal   |vauthors=Nomura N, Miyajima N, Sazuka T, etal |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27–35 |year= 1995 |pmid= 7584026 |doi=10.1093/dnares/1.1.27 }}
*{{cite journal | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47-56 |year= 1995 |pmid= 7584028 |doi= }}
*{{cite journal   |vauthors=Nomura N, Miyajima N, Sazuka T, etal |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47–56 |year= 1995 |pmid= 7584028 |doi=10.1093/dnares/1.1.47  }}
*{{cite journal  | author=Pai CY, Chen HK, Sheu HL, Yeh NH |title=Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis. |journal=J. Cell. Sci. |volume=108 ( Pt 5) |issue= |pages= 1911-20 |year= 1995 |pmid= 7657714 |doi=  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
*{{cite journal  |vauthors=Pai CY, Yeh NH |title=Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130. |journal=Biochem. Biophys. Res. Commun. |volume=221 |issue= 3 |pages= 581–7 |year= 1996 |pmid= 8630004 |doi= 10.1006/bbrc.1996.0639 }}
*{{cite journal  | author=Pai CY, Yeh NH |title=Cell proliferation-dependent expression of two isoforms of the nucleolar phosphoprotein p130. |journal=Biochem. Biophys. Res. Commun. |volume=221 |issue= 3 |pages= 581-7 |year= 1996 |pmid= 8630004 |doi= 10.1006/bbrc.1996.0639 }}
*{{cite journal  |vauthors=Miau LH, Chang CJ, Tsai WH, Lee SC |title=Identification and characterization of a nucleolar phosphoprotein, Nopp140, as a transcription factor. |journal=Mol. Cell. Biol. |volume=17 |issue= 1 |pages= 230–9 |year= 1997 |pmid= 8972203 |doi= | pmc=231747  }}
*{{cite journal  | author=Miau LH, Chang CJ, Tsai WH, Lee SC |title=Identification and characterization of a nucleolar phosphoprotein, Nopp140, as a transcription factor. |journal=Mol. Cell. Biol. |volume=17 |issue= 1 |pages= 230-9 |year= 1997 |pmid= 8972203 |doi=  }}
*{{cite journal  |vauthors=Li D, Meier UT, Dobrowolska G, Krebs EG |title=Specific interaction between casein kinase 2 and the nucleolar protein Nopp140. |journal=J. Biol. Chem. |volume=272 |issue= 6 |pages= 3773–9 |year= 1997 |pmid= 9013635 |doi=10.1074/jbc.272.6.3773 }}
*{{cite journal  | author=Li D, Meier UT, Dobrowolska G, Krebs EG |title=Specific interaction between casein kinase 2 and the nucleolar protein Nopp140. |journal=J. Biol. Chem. |volume=272 |issue= 6 |pages= 3773-9 |year= 1997 |pmid= 9013635 |doi= }}
*{{cite journal  |vauthors=Chen HK, Yeh NH |title=The nucleolar phosphoprotein P130 is a GTPase/ATPase with intrinsic property to form large complexes triggered by F- and Mg2+. |journal=Biochem. Biophys. Res. Commun. |volume=230 |issue= 2 |pages= 370–5 |year= 1997 |pmid= 9016786 |doi= 10.1006/bbrc.1996.5966 }}
*{{cite journal | author=Chen HK, Yeh NH |title=The nucleolar phosphoprotein P130 is a GTPase/ATPase with intrinsic property to form large complexes triggered by F- and Mg2+. |journal=Biochem. Biophys. Res. Commun. |volume=230 |issue= 2 |pages= 370-5 |year= 1997 |pmid= 9016786 |doi= 10.1006/bbrc.1996.5966 }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal   |vauthors=Miau LH, Chang CJ, Shen BJ, etal |title=Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation. |journal=J. Biol. Chem. |volume=273 |issue= 17 |pages= 10784–91 |year= 1998 |pmid= 9553145 |doi=10.1074/jbc.273.17.10784 }}
*{{cite journal  | author=Miau LH, Chang CJ, Shen BJ, ''et al.'' |title=Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation. |journal=J. Biol. Chem. |volume=273 |issue= 17 |pages= 10784-91 |year= 1998 |pmid= 9553145 |doi= }}
*{{cite journal  |vauthors=Isaac C, Yang Y, Meier UT |title=Nopp140 functions as a molecular link between the nucleolus and the coiled bodies. |journal=J. Cell Biol. |volume=142 |issue= 2 |pages= 319–29 |year= 1998 |pmid= 9679133 |doi=10.1083/jcb.142.2.319  | pmc=2133063  }}
*{{cite journal  | author=Isaac C, Yang Y, Meier UT |title=Nopp140 functions as a molecular link between the nucleolus and the coiled bodies. |journal=J. Cell Biol. |volume=142 |issue= 2 |pages= 319-29 |year= 1998 |pmid= 9679133 |doi= }}
*{{cite journal  |vauthors=Blanchette P, Gilchrist CA, Baker RT, Gray DA |title=Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130. |journal=Oncogene |volume=20 |issue= 39 |pages= 5533–7 |year= 2001 |pmid= 11571651 |doi= 10.1038/sj.onc.1204823 }}
*{{cite journal  | author=Chen HK, Pai CY, Huang JY, Yeh NH |title=Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structural organization. |journal=Mol. Cell. Biol. |volume=19 |issue= 12 |pages= 8536-46 |year= 2000 |pmid= 10567578 |doi= }}
*{{cite journal  |vauthors=Chiu CM, Tsay YG, Chang CJ, Lee SC |title=Nopp140 is a mediator of the protein kinase A signaling pathway that activates the acute phase response alpha1-acid glycoprotein gene. |journal=J. Biol. Chem. |volume=277 |issue= 42 |pages= 39102–11 |year= 2002 |pmid= 12167624 |doi= 10.1074/jbc.M205915200 }}
*{{cite journal  | author=Blanchette P, Gilchrist CA, Baker RT, Gray DA |title=Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130. |journal=Oncogene |volume=20 |issue= 39 |pages= 5533-7 |year= 2001 |pmid= 11571651 |doi= 10.1038/sj.onc.1204823 }}
*{{cite journal  |vauthors=Wang C, Query CC, Meier UT |title=Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140. |journal=Mol. Cell. Biol. |volume=22 |issue= 24 |pages= 8457–66 |year= 2003 |pmid= 12446766 |doi=10.1128/MCB.22.24.8457-8466.2002  | pmc=139890  }}
*{{cite journal | author=Chiu CM, Tsay YG, Chang CJ, Lee SC |title=Nopp140 is a mediator of the protein kinase A signaling pathway that activates the acute phase response alpha1-acid glycoprotein gene. |journal=J. Biol. Chem. |volume=277 |issue= 42 |pages= 39102-11 |year= 2002 |pmid= 12167624 |doi= 10.1074/jbc.M205915200 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal | author=Wang C, Query CC, Meier UT |title=Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated Nopp140. |journal=Mol. Cell. Biol. |volume=22 |issue= 24 |pages= 8457-66 |year= 2003 |pmid= 12446766 |doi= }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Brill LM, Salomon AR, Ficarro SB, etal |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763–72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Brandenberger R, Wei H, Zhang S, etal |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 }}
*{{cite journal | author=Brill LM, Salomon AR, Ficarro SB, ''et al.'' |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763-72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d }}
*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
*{{cite journal | author=Brandenberger R, Wei H, Zhang S, ''et al.'' |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707-16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 }}
*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
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Revision as of 23:41, 6 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nucleolar phosphoprotein p130 is a protein that in humans is encoded by the NOLC1 gene.[1][2][3]


Interactions

Nucleolar phosphoprotein p130 has been shown to interact with Coilin[4] and CEBPB.[5]

References

  1. Pai CY, Chen HK, Sheu HL, Yeh NH (Oct 1995). "Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis". J Cell Sci. 108. ( Pt 5): 1911–20. PMID 7657714.
  2. Chen HK, Pai CY, Huang JY, Yeh NH (Jan 2000). "Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structural organization". Mol Cell Biol. 19 (12): 8536–46. PMC 84972. PMID 10567578.
  3. "Entrez Gene: NOLC1 nucleolar and coiled-body phosphoprotein 1".
  4. Isaac, C; Yang Y; Meier U T (Jul 1998). "Nopp140 functions as a molecular link between the nucleolus and the coiled bodies". J. Cell Biol. UNITED STATES. 142 (2): 319–29. doi:10.1083/jcb.142.2.319. ISSN 0021-9525. PMC 2133063. PMID 9679133.
  5. Miau, L H; Chang C J; Shen B J; Tsai W H; Lee S C (Apr 1998). "Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation". J. Biol. Chem. UNITED STATES. 273 (17): 10784–91. doi:10.1074/jbc.273.17.10784. ISSN 0021-9258. PMID 9553145.

Further reading