LMO1: Difference between revisions

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Revision as of 18:01, 2 September 2017

Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene.^[1]^[2]^[3]

LMO1 encodes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.^[3]

Interactions

LMO1 has been shown to interact with GATA3^[4]^[5] and TAL1.^[6]^[7]

References

↑ Boehm T, Foroni L, Kaneko Y, Perutz MF, Rabbitts TH (June 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. 88 (10): 4367–71. doi:10.1073/pnas.88.10.4367. PMC 51660. PMID 2034676.
↑ McGuire EA, Davis AR, Korsmeyer SJ (March 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. 77 (3): 599–606. PMID 1703797.
↑ ^3.0 ^3.1 "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)".
↑ Ono, Y; Fukuhara N; Yoshie O (December 1998). "TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3". Mol. Cell. Biol. UNITED STATES. 18 (12): 6939–50. ISSN 0270-7306. PMC 109277. PMID 9819382.
↑ Ono, Y; Fukuhara N; Yoshie O (February 1997). "Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL". J. Biol. Chem. UNITED STATES. 272 (7): 4576–81. doi:10.1074/jbc.272.7.4576. ISSN 0021-9258. PMID 9020185.
↑ Valge-Archer, V E; Osada H; Warren A J; Forster A; Li J; Baer R; Rabbitts T H (August 1994). "The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells". Proc. Natl. Acad. Sci. U.S.A. UNITED STATES. 91 (18): 8617–21. doi:10.1073/pnas.91.18.8617. ISSN 0027-8424. PMC 44657. PMID 8078932.
↑ Wadman, I; Li J; Bash R O; Forster A; Osada H; Rabbitts T H; Baer R (October 1994). "Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia". EMBO J. ENGLAND. 13 (20): 4831–9. ISSN 0261-4189. PMC 395422. PMID 7957052.

Foroni L, Boehm T, White L, et al. (1992). "The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development". J. Mol. Biol. 226 (3): 747–61. doi:10.1016/0022-2836(92)90630-3. PMID 1507224.
Boehm T, Spillantini MG, Sofroniew MV, et al. (1991). "Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression". Oncogene. 6 (5): 695–703. PMID 2052354.
Chen Q, Cheng JT, Tasi LH, et al. (1990). "The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein". EMBO J. 9 (2): 415–24. PMC 551682. PMID 2303035.
Boehm T, Greenberg JM, Buluwela L, et al. (1990). "An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs". EMBO J. 9 (3): 857–68. PMC 551746. PMID 2311586.
McGuire EA, Hockett RD, Pollock KM, et al. (1989). "The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein". Mol. Cell. Biol. 9 (5): 2124–32. PMC 363006. PMID 2501659.
Boehm T, Baer R, Lavenir I, et al. (1988). "The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15". EMBO J. 7 (2): 385–94. PMC 454331. PMID 3259177.
Wadman I, Li J, Bash RO, et al. (1994). "Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia". EMBO J. 13 (20): 4831–9. PMC 395422. PMID 7957052.
Valge-Archer VE, Osada H, Warren AJ, et al. (1994). "The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells". Proc. Natl. Acad. Sci. U.S.A. 91 (18): 8617–21. doi:10.1073/pnas.91.18.8617. PMC 44657. PMID 8078932.
Arber S, Caroni P (1996). "Specificity of single LIM motifs in targeting and LIM/LIM interactions in situ". Genes Dev. 10 (3): 289–300. doi:10.1101/gad.10.3.289. PMID 8595880.
Jurata LW, Kenny DA, Gill GN (1996). "Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development". Proc. Natl. Acad. Sci. U.S.A. 93 (21): 11693–8. doi:10.1073/pnas.93.21.11693. PMC 38120. PMID 8876198.
Ono Y, Fukuhara N, Yoshie O (1997). "Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL". J. Biol. Chem. 272 (7): 4576–81. doi:10.1074/jbc.272.7.4576. PMID 9020185.
Valge-Archer V, Forster A, Rabbitts TH (1999). "The LMO1 and LDB1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t(11;14)(p15;q11)". Oncogene. 17 (24): 3199–202. doi:10.1038/sj.onc.1202353. PMID 9872335.
Bao J, Talmage DA, Role LW, Gautier J (2000). "Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins". Development. 127 (2): 425–35. PMID 10603358.
Cichutek A, Brueckmann T, Seipel B, et al. (2001). "Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1)". Cytogenet. Cell Genet. 93 (3–4): 277–83. doi:10.1159/000056998. PMID 11528126.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Lin YW, Deveney R, Barbara M, et al. (2005). "OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1". Cancer Res. 65 (16): 7151–8. doi:10.1158/0008-5472.CAN-05-1400. PMC 1681523. PMID 16103065.
Saeki N, Kim DH, Usui T, et al. (2007). "GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling". Oncogene. 26 (45): 6488–98. doi:10.1038/sj.onc.1210475. PMID 17471240.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[pmid2034676-1] Boehm T, Foroni L, Kaneko Y, Perutz MF, Rabbitts TH (June 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. 88 (10): 4367–71. doi:10.1073/pnas.88.10.4367. PMC 51660. PMID 2034676.

[pmid1703797-2] McGuire EA, Davis AR, Korsmeyer SJ (March 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. 77 (3): 599–606. PMID 1703797.

[entrez-3] 3.0 ^3.1 "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)".

[pmid9819382-4] Ono, Y; Fukuhara N; Yoshie O (December 1998). "TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3". Mol. Cell. Biol. UNITED STATES. 18 (12): 6939–50. ISSN 0270-7306. PMC 109277. PMID 9819382.

[pmid9020185-5] Ono, Y; Fukuhara N; Yoshie O (February 1997). "Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL". J. Biol. Chem. UNITED STATES. 272 (7): 4576–81. doi:10.1074/jbc.272.7.4576. ISSN 0021-9258. PMID 9020185.

[pmid8078932-6] Valge-Archer, V E; Osada H; Warren A J; Forster A; Li J; Baer R; Rabbitts T H (August 1994). "The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells". Proc. Natl. Acad. Sci. U.S.A. UNITED STATES. 91 (18): 8617–21. doi:10.1073/pnas.91.18.8617. ISSN 0027-8424. PMC 44657. PMID 8078932.

[pmid7957052-7] Wadman, I; Li J; Bash R O; Forster A; Osada H; Rabbitts T H; Baer R (October 1994). "Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia". EMBO J. ENGLAND. 13 (20): 4831–9. ISSN 0261-4189. PMC 395422. PMID 7957052.

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-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Rhombotin-1''' is a [[protein]] that in humans is encoded by the ''LMO1'' [[gene]].<ref name="pmid2034676">{{cite journal |vauthors=Boehm T, Foroni L, Kaneko Y, Perutz MF, Rabbitts TH | title = The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13 | journal = Proc Natl Acad Sci U S A | volume = 88 | issue = 10 | pages = 4367–71 |date=June 1991 | pmid = 2034676 | pmc = 51660 | doi =10.1073/pnas.88.10.4367  }}</ref><ref name="pmid1703797">{{cite journal |vauthors=McGuire EA, Davis AR, Korsmeyer SJ | title = T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells | journal = Blood | volume = 77 | issue = 3 | pages = 599–606 |date=March 1991 | pmid = 1703797 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4004| accessdate = }}</ref>
-| update_page = yes
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-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = LIM domain only 1 (rhombotin 1)
- | HGNCid = 6641
- | Symbol = LMO1
- | AltSymbols =; MGC116692; RBTN1; RHOM1; TTG1
- | OMIM = 186921
- | ECnumber =
- | Homologene = 48101
- | MGIid = 102812
- | GeneAtlas_image1 = PBB_GE_LMO1_206718_at_tn.png
-  | Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}}
-  | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 4004
-    | Hs_Ensembl = ENSG00000166407
-    | Hs_RefseqProtein = NP_002306
-    | Hs_RefseqmRNA = NM_002315
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 11
-    | Hs_GenLoc_start = 8202437
-    | Hs_GenLoc_end = 8246758
-    | Hs_Uniprot = P25800
-    | Mm_EntrezGene = 109594
-    | Mm_Ensembl = ENSMUSG00000036111
-    | Mm_RefseqmRNA = NM_057173
-    | Mm_RefseqProtein = NP_476514
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 108930048
-    | Mm_GenLoc_end = 108934847
-    | Mm_Uniprot = Q3UZX1
-  }}
-}}
-'''LIM domain only 1 (rhombotin 1)''', also known as '''LMO1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4004| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = LMO1 enocdes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.<ref name="entrez">{{cite web | title = Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4004| accessdate = }}</ref>
+| summary_text = LMO1 encodes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.<ref name="entrez"/>
 }}
+==Interactions==
+LMO1 has been shown to [[Protein-protein interaction|interact]] with [[GATA3]]<ref name=pmid9819382>{{cite journal |last=Ono |first=Y |authorlink= |author2=Fukuhara N |author3=Yoshie O  |date=December 1998  |title=TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3 |journal=Mol. Cell. Biol. |volume=18 |issue=12 |pages=6939–50 |publisher= |location = UNITED STATES| issn = 0270-7306| pmid = 9819382 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=109277 }}</ref><ref name=pmid9020185>{{cite journal |last=Ono |first=Y |authorlink= |author2=Fukuhara N |author3=Yoshie O  |date=February 1997  |title=Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL |journal=J. Biol. Chem. |volume=272 |issue=7 |pages=4576–81 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9020185 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.272.7.4576 }}</ref> and [[TAL1]].<ref name=pmid8078932>{{cite journal |last=Valge-Archer |first=V E |authorlink= |author2=Osada H |author3=Warren A J |author4=Forster A |author5=Li J |author6=Baer R |author7=Rabbitts T H  |date=August 1994  |title=The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=91 |issue=18 |pages=8617–21 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8078932 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1073/pnas.91.18.8617 |pmc=44657 }}</ref><ref name=pmid7957052>{{cite journal |last=Wadman |first=I |authorlink= |author2=Li J |author3=Bash R O |author4=Forster A |author5=Osada H |author6=Rabbitts T H |author7=Baer R  |date=October 1994  |title=Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia |journal=EMBO J. |volume=13 |issue=20 |pages=4831–9 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 7957052 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=395422 }}</ref>
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Foroni L, Boehm T, White L, ''et al.'' |title=The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. |journal=J. Mol. Biol. |volume=226 |issue= 3 |pages= 747-61 |year= 1992 |pmid= 1507224 |doi=  }}
+*{{cite journal   |vauthors=Foroni L, Boehm T, White L, etal |title=The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. |journal=J. Mol. Biol. |volume=226 |issue= 3 |pages= 747–61 |year= 1992 |pmid= 1507224 |doi=10.1016/0022-2836(92)90630-3  }}
-*{{cite journal  | author=McGuire EA, Davis AR, Korsmeyer SJ |title=T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells. |journal=Blood |volume=77 |issue= 3 |pages= 599-606 |year= 1991 |pmid= 1703797 |doi=  }}
+*{{cite journal   |vauthors=Boehm T, Spillantini MG, Sofroniew MV, etal |title=Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression. |journal=Oncogene |volume=6 |issue= 5 |pages= 695–703 |year= 1991 |pmid= 2052354 |doi=  }}
-*{{cite journal  | author=Boehm T, Foroni L, Kaneko Y, ''et al.'' |title=The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 10 |pages= 4367-71 |year= 1991 |pmid= 2034676 |doi=  }}
+*{{cite journal   |vauthors=Chen Q, Cheng JT, Tasi LH, etal |title=The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. |journal=EMBO J. |volume=9 |issue= 2 |pages= 415–24 |year= 1990 |pmid= 2303035 |doi=  | pmc=551682  }}
-*{{cite journal  | author=Boehm T, Spillantini MG, Sofroniew MV, ''et al.'' |title=Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression. |journal=Oncogene |volume=6 |issue= 5 |pages= 695-703 |year= 1991 |pmid= 2052354 |doi=  }}
+*{{cite journal   |vauthors=Boehm T, Greenberg JM, Buluwela L, etal |title=An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs. |journal=EMBO J. |volume=9 |issue= 3 |pages= 857–68 |year= 1990 |pmid= 2311586 |doi=  | pmc=551746  }}
-*{{cite journal  | author=Chen Q, Cheng JT, Tasi LH, ''et al.'' |title=The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. |journal=EMBO J. |volume=9 |issue= 2 |pages= 415-24 |year= 1990 |pmid= 2303035 |doi=  }}
+*{{cite journal   |vauthors=McGuire EA, Hockett RD, Pollock KM, etal |title=The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. |journal=Mol. Cell. Biol. |volume=9 |issue= 5 |pages= 2124–32 |year= 1989 |pmid= 2501659 |doi=  | pmc=363006  }}
-*{{cite journal  | author=Boehm T, Greenberg JM, Buluwela L, ''et al.'' |title=An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs. |journal=EMBO J. |volume=9 |issue= 3 |pages= 857-68 |year= 1990 |pmid= 2311586 |doi=  }}
+*{{cite journal   |vauthors=Boehm T, Baer R, Lavenir I, etal |title=The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15. |journal=EMBO J. |volume=7 |issue= 2 |pages= 385–94 |year= 1988 |pmid= 3259177 |doi=  | pmc=454331  }}
-*{{cite journal  | author=McGuire EA, Hockett RD, Pollock KM, ''et al.'' |title=The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. |journal=Mol. Cell. Biol. |volume=9 |issue= 5 |pages= 2124-32 |year= 1989 |pmid= 2501659 |doi=  }}
+*{{cite journal   |vauthors=Wadman I, Li J, Bash RO, etal |title=Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. |journal=EMBO J. |volume=13 |issue= 20 |pages= 4831–9 |year= 1994 |pmid= 7957052 |doi=  | pmc=395422  }}
-*{{cite journal  | author=Boehm T, Baer R, Lavenir I, ''et al.'' |title=The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15. |journal=EMBO J. |volume=7 |issue= 2 |pages= 385-94 |year= 1988 |pmid= 3259177 |doi=  }}
+*{{cite journal   |vauthors=Valge-Archer VE, Osada H, Warren AJ, etal |title=The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 18 |pages= 8617–21 |year= 1994 |pmid= 8078932 |doi=10.1073/pnas.91.18.8617  | pmc=44657  }}
-*{{cite journal  | author=Wadman I, Li J, Bash RO, ''et al.'' |title=Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. |journal=EMBO J. |volume=13 |issue= 20 |pages= 4831-9 |year= 1994 |pmid= 7957052 |doi=  }}
+*{{cite journal  |vauthors=Arber S, Caroni P |title=Specificity of single LIM motifs in targeting and LIM/LIM interactions in situ. |journal=Genes Dev. |volume=10 |issue= 3 |pages= 289–300 |year= 1996 |pmid= 8595880 |doi=10.1101/gad.10.3.289  }}
-*{{cite journal  | author=Valge-Archer VE, Osada H, Warren AJ, ''et al.'' |title=The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 18 |pages= 8617-21 |year= 1994 |pmid= 8078932 |doi=  }}
+*{{cite journal  |vauthors=Jurata LW, Kenny DA, Gill GN |title=Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 21 |pages= 11693–8 |year= 1996 |pmid= 8876198 |doi=10.1073/pnas.93.21.11693  | pmc=38120  }}
-*{{cite journal  | author=Arber S, Caroni P |title=Specificity of single LIM motifs in targeting and LIM/LIM interactions in situ. |journal=Genes Dev. |volume=10 |issue= 3 |pages= 289-300 |year= 1996 |pmid= 8595880 |doi=  }}
+*{{cite journal  |vauthors=Ono Y, Fukuhara N, Yoshie O |title=Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL. |journal=J. Biol. Chem. |volume=272 |issue= 7 |pages= 4576–81 |year= 1997 |pmid= 9020185 |doi=10.1074/jbc.272.7.4576  }}
-*{{cite journal  | author=Jurata LW, Kenny DA, Gill GN |title=Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 21 |pages= 11693-8 |year= 1996 |pmid= 8876198 |doi=  }}
+*{{cite journal  |vauthors=Valge-Archer V, Forster A, Rabbitts TH |title=The LMO1 and LDB1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t(11;14)(p15;q11). |journal=Oncogene |volume=17 |issue= 24 |pages= 3199–202 |year= 1999 |pmid= 9872335 |doi= 10.1038/sj.onc.1202353 }}
-*{{cite journal  | author=Ono Y, Fukuhara N, Yoshie O |title=Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL. |journal=J. Biol. Chem. |volume=272 |issue= 7 |pages= 4576-81 |year= 1997 |pmid= 9020185 |doi=  }}
+*{{cite journal  |vauthors=Bao J, Talmage DA, Role LW, Gautier J |title=Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins. |journal=Development |volume=127 |issue= 2 |pages= 425–35 |year= 2000 |pmid= 10603358 |doi=  }}
-*{{cite journal  | author=Valge-Archer V, Forster A, Rabbitts TH |title=The LMO1 and LDB1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t(11;14)(p15;q11). |journal=Oncogene |volume=17 |issue= 24 |pages= 3199-202 |year= 1999 |pmid= 9872335 |doi= 10.1038/sj.onc.1202353 }}
+*{{cite journal   |vauthors=Cichutek A, Brueckmann T, Seipel B, etal |title=Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1). |journal=Cytogenet. Cell Genet. |volume=93 |issue= 3–4 |pages= 277–83 |year= 2001 |pmid= 11528126 |doi=10.1159/000056998  }}
-*{{cite journal  | author=Bao J, Talmage DA, Role LW, Gautier J |title=Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins. |journal=Development |volume=127 |issue= 2 |pages= 425-35 |year= 2000 |pmid= 10603358 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Cichutek A, Brueckmann T, Seipel B, ''et al.'' |title=Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1). |journal=Cytogenet. Cell Genet. |volume=93 |issue= 3-4 |pages= 277-83 |year= 2001 |pmid= 11528126 |doi=  }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Lin YW, Deveney R, Barbara M, etal |title=OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1 |journal=Cancer Res. |volume=65 |issue= 16 |pages= 7151–8 |year= 2005 |pmid= 16103065 |doi= 10.1158/0008-5472.CAN-05-1400  | pmc=1681523 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Saeki N, Kim DH, Usui T, etal |title=GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling |journal=Oncogene |volume=26 |issue= 45 |pages= 6488–98 |year= 2007 |pmid= 17471240 |doi= 10.1038/sj.onc.1210475 }}
-*{{cite journal  | author=Lin YW, Deveney R, Barbara M, ''et al.'' |title=OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1. |journal=Cancer Res. |volume=65 |issue= 16 |pages= 7151-8 |year= 2005 |pmid= 16103065 |doi= 10.1158/0008-5472.CAN-05-1400 }}
-*{{cite journal  | author=Saeki N, Kim DH, Usui T, ''et al.'' |title=GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling. |journal=Oncogene |volume=26 |issue= 45 |pages= 6488-98 |year= 2007 |pmid= 17471240 |doi= 10.1038/sj.onc.1210475 }}
 }}
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LMO1: Difference between revisions

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