RBM4: Difference between revisions

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{{Underlinked|date=June 2016}}
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{{Infobox_gene}}
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'''RNA-binding protein 4''' is a [[protein]] that in humans is encoded by the ''RBM4'' [[gene]].<ref name="pmid9169144">{{cite journal | vauthors = Jackson FR, Banfi S, Guffanti A, Rossi E | title = A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans | journal = Genomics | volume = 41 | issue = 3 | pages = 444–52 |date=Jul 1997 | pmid = 9169144 | pmc =  | doi = 10.1006/geno.1997.4704 }}</ref><ref name="pmid16260624">{{cite journal | vauthors = Lin JC, Tarn WY | title = Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB | journal = Mol Cell Biol | volume = 25 | issue = 22 | pages = 10111–21 |date=Nov 2005 | pmid = 16260624 | pmc = 1280272 | doi = 10.1128/MCB.25.22.10111-10121.2005 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RBM4 RNA binding motif protein 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5936| accessdate = }}</ref>
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{{GNF_Protein_box
| image = PBB_Protein_RBM4_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2dgt.
| PDB = {{PDB2|2dgt}}, {{PDB2|2dnq}}
| Name = RNA binding motif protein 4
| HGNCid = 9901
| Symbol = RBM4
| AltSymbols =; DKFZp547K0918; LARK; MGC75138; RBM4A; ZCCHC21; ZCRB3A
| OMIM = 602571
| ECnumber =
| Homologene = 82510
| MGIid = 1100865
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}} {{GNF_GO|id=GO:0016068 |text = type I hypersensitivity}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5936
    | Hs_Ensembl =
    | Hs_RefseqProtein = NP_002887
    | Hs_RefseqmRNA = NM_002896
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 19653
    | Mm_Ensembl = ENSMUSG00000056951
    | Mm_RefseqmRNA = NM_009032
    | Mm_RefseqProtein = NP_033058
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 19
    | Mm_GenLoc_start = 4784293
    | Mm_GenLoc_end = 4793877
    | Mm_Uniprot = Q5CZX8
  }}
}}
'''RNA binding motif protein 4''', also known as '''RBM4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RBM4 RNA binding motif protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5936| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
*{{cite journal  | author=Jackson FR, Banfi S, Guffanti A, Rossi E |title=A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans. |journal=Genomics |volume=41 |issue= 3 |pages= 444-52 |year= 1997 |pmid= 9169144 |doi= 10.1006/geno.1997.4704 }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal   |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 }}
*{{cite journal | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
*{{cite journal  | vauthors=Bernert G, Fountoulakis M, Lubec G |title=Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain. |journal=Proteomics |volume=2 |issue= 12 |pages= 1752–7 |year= 2003 |pmid= 12469345 |doi= 10.1002/1615-9861(200212)2:12<1752::AID-PROT1752>3.0.CO;2-Y }}
*{{cite journal  | author=Bernert G, Fountoulakis M, Lubec G |title=Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain. |journal=Proteomics |volume=2 |issue= 12 |pages= 1752-7 |year= 2003 |pmid= 12469345 |doi= 10.1002/1615-9861(200212)2:12<1752::AID-PROT1752>3.0.CO;2-Y }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Petersen HH, Hilpert J, Militz D, etal |title=Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule. |journal=J. Cell Sci. |volume=116 |issue= Pt 3 |pages= 453–61 |year= 2003 |pmid= 12508107 |doi=10.1242/jcs.00243 }}
*{{cite journal | author=Petersen HH, Hilpert J, Militz D, ''et al.'' |title=Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule. |journal=J. Cell. Sci. |volume=116 |issue= Pt 3 |pages= 453-61 |year= 2003 |pmid= 12508107 |doi=  }}
*{{cite journal  | vauthors=Lai MC, Kuo HW, Chang WC, Tarn WY |title=A novel splicing regulator shares a nuclear import pathway with SR proteins. |journal=EMBO J. |volume=22 |issue= 6 |pages= 1359–69 |year= 2003 |pmid= 12628928 |doi= 10.1093/emboj/cdg126 | pmc=151058 }}
*{{cite journal  | author=Lai MC, Kuo HW, Chang WC, Tarn WY |title=A novel splicing regulator shares a nuclear import pathway with SR proteins. |journal=EMBO J. |volume=22 |issue= 6 |pages= 1359-69 |year= 2003 |pmid= 12628928 |doi= 10.1093/emboj/cdg126 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Diederichs S, Bäumer N, Ji P, etal |title=Identification of interaction partners and substrates of the cyclin A1-CDK2 complex. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33727–41 |year= 2004 |pmid= 15159402 |doi= 10.1074/jbc.M401708200 }}
*{{cite journal | author=Diederichs S, Bäumer N, Ji P, ''et al.'' |title=Identification of interaction partners and substrates of the cyclin A1-CDK2 complex. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33727-41 |year= 2004 |pmid= 15159402 |doi= 10.1074/jbc.M401708200 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Rush J, Moritz A, Lee KA, etal |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal | author=Rush J, Moritz A, Lee KA, ''et al.'' |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94-101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Lin JC, Tarn WY |title=Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB. |journal=Mol. Cell. Biol. |volume=25 |issue= 22 |pages= 10111-21 |year= 2005 |pmid= 16260624 |doi= 10.1128/MCB.25.22.10111-10121.2005 }}
*{{cite journal  | vauthors=Kar A, Havlioglu N, Tarn WY, Wu JY |title=RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion. |journal=J. Biol. Chem. |volume=281 |issue= 34 |pages= 24479–88 |year= 2006 |pmid= 16777844 |doi= 10.1074/jbc.M603971200 | pmc=2072872 }}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal   |vauthors=Markus MA, Heinrich B, Raitskin O, etal |title=WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. |journal=Exp. Cell Res. |volume=312 |issue= 17 |pages= 3379–88 |year= 2006 |pmid= 16934801 |doi= 10.1016/j.yexcr.2006.07.008 }}
*{{cite journal  | author=Kar A, Havlioglu N, Tarn WY, Wu JY |title=RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion. |journal=J. Biol. Chem. |volume=281 |issue= 34 |pages= 24479-88 |year= 2006 |pmid= 16777844 |doi= 10.1074/jbc.M603971200 }}
*{{cite journal  | vauthors=Lin JC, Hsu M, Tarn WY |title=Cell stress modulates the function of splicing regulatory protein RBM4 in translation control. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 7 |pages= 2235–40 |year= 2007 |pmid= 17284590 |doi= 10.1073/pnas.0611015104 | pmc=1893002 }}
*{{cite journal | author=Markus MA, Heinrich B, Raitskin O, ''et al.'' |title=WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. |journal=Exp. Cell Res. |volume=312 |issue= 17 |pages= 3379-88 |year= 2006 |pmid= 16934801 |doi= 10.1016/j.yexcr.2006.07.008 }}
*{{cite journal  | author=Lin JC, Hsu M, Tarn WY |title=Cell stress modulates the function of splicing regulatory protein RBM4 in translation control. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 7 |pages= 2235-40 |year= 2007 |pmid= 17284590 |doi= 10.1073/pnas.0611015104 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=5936}}
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Revision as of 20:43, 8 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

RNA-binding protein 4 is a protein that in humans is encoded by the RBM4 gene.[1][2][3]


References

  1. ↑ Jackson FR, Banfi S, Guffanti A, Rossi E (Jul 1997). "A novel zinc finger-containing RNA-binding protein conserved from fruitflies to humans". Genomics. 41 (3): 444–52. doi:10.1006/geno.1997.4704. PMID 9169144.
  2. ↑ Lin JC, Tarn WY (Nov 2005). "Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB". Mol Cell Biol. 25 (22): 10111–21. doi:10.1128/MCB.25.22.10111-10121.2005. PMC 1280272. PMID 16260624.
  3. ↑ "Entrez Gene: RBM4 RNA binding motif protein 4".

Further reading



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