CHST1: Difference between revisions

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{{Infobox_gene}}
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'''Carbohydrate sulfotransferase 1''' is an [[enzyme]] that in humans is encoded by the ''CHST1'' [[gene]].<ref name="pmid9405439">{{cite journal | vauthors = Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O | title = Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase | journal = J Biol Chem | volume = 272 | issue = 51 | pages = 32321–8 |date=Jan 1998 | pmid = 9405439 | pmc =  | doi =10.1074/jbc.272.51.32321 }}</ref><ref name="pmid9639683">{{cite journal | vauthors = Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ | title = Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization | journal = Biochim Biophys Acta | volume = 1407 | issue = 1 | pages = 92–7 |date=Aug 1998 | pmid = 9639683 | pmc =  | doi =  10.1016/s0925-4439(98)00028-3}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8534| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
| HGNCid = 1969
| Symbol = CHST1
| AltSymbols =; C6ST; KS6ST; KSGal6ST
| OMIM = 603797
| ECnumber =
| Homologene = 2711
| MGIid = 1924219
  | GeneAtlas_image1 = PBB_GE_CHST1_205567_at_tn.png
  | Function = {{GNF_GO|id=GO:0016740 |text = transferase activity}} {{GNF_GO|id=GO:0045130 |text = keratan sulfotransferase activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0031228 |text = intrinsic to Golgi membrane}}
| Process = {{GNF_GO|id=GO:0005976 |text = polysaccharide metabolic process}} {{GNF_GO|id=GO:0006012 |text = galactose metabolic process}} {{GNF_GO|id=GO:0006954 |text = inflammatory response}} {{GNF_GO|id=GO:0042339 |text = keratan sulfate metabolic process}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8534
    | Hs_Ensembl = ENSG00000175264
    | Hs_RefseqProtein = NP_003645
    | Hs_RefseqmRNA = NM_003654
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 11
    | Hs_GenLoc_start = 45627003
    | Hs_GenLoc_end = 45643748
    | Hs_Uniprot = O43916
    | Mm_EntrezGene = 76969
    | Mm_Ensembl = ENSMUSG00000027221
    | Mm_RefseqmRNA = NM_023850
    | Mm_RefseqProtein = NP_076339
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 92412612
    | Mm_GenLoc_end = 92416089
    | Mm_Uniprot = Q3UY35
  }}
}}
'''Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1''', also known as '''CHST1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8534| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CHST1}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Williams KJ |title=Atherosclerosis: cell biology and lipoproteins. |journal=Curr. Opin. Lipidol. |volume=7 |issue= 6 |pages= U202-8 |year= 1997 |pmid= 9117134 |doi=  }}
*{{cite journal  | author=Williams KJ |title=Atherosclerosis: cell biology and lipoproteins. |journal=Curr. Opin. Lipidol. |volume=7 |issue= 6 |pages= U202–8 |year= 1997 |pmid= 9117134 |doi=10.1097/00041433-199612000-00016 }}
*{{cite journal  | author=Bernstein HB, Compans RW |title=Sulfation of the human immunodeficiency virus envelope glycoprotein. |journal=J. Virol. |volume=66 |issue= 12 |pages= 6953-9 |year= 1992 |pmid= 1433500 |doi=  }}
*{{cite journal  | vauthors=Bernstein HB, Compans RW |title=Sulfation of the human immunodeficiency virus envelope glycoprotein. |journal=J. Virol. |volume=66 |issue= 12 |pages= 6953–9 |year= 1992 |pmid= 1433500 |doi= | pmc=240329 }}
*{{cite journal  | author=Shilatifard A, Merkle RK, Helland DE, ''et al.'' |title=Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine. |journal=J. Virol. |volume=67 |issue= 2 |pages= 943-52 |year= 1993 |pmid= 8419650 |doi=  }}
*{{cite journal  | vauthors=Shilatifard A, Merkle RK, Helland DE |title=Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine. |journal=J. Virol. |volume=67 |issue= 2 |pages= 943–52 |year= 1993 |pmid= 8419650 |doi=  | pmc=237448 |display-authors=etal}}
*{{cite journal  | author=Fukuta M, Inazawa J, Torii T, ''et al.'' |title=Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase. |journal=J. Biol. Chem. |volume=272 |issue= 51 |pages= 32321-8 |year= 1998 |pmid= 9405439 |doi= }}
*{{cite journal  | vauthors=Li X, Tedder TF |title=CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization. |journal=Genomics |volume=55 |issue= 3 |pages= 345–7 |year= 1999 |pmid= 10049591 |doi= 10.1006/geno.1998.5653 }}
*{{cite journal | author=Mazany KD, Peng T, Watson CE, ''et al.'' |title=Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization. |journal=Biochim. Biophys. Acta |volume=1407 |issue= 1 |pages= 92-7 |year= 1998 |pmid= 9639683 |doi=  }}
*{{cite journal  | vauthors=Bistrup A, Bhakta S, Lee JK |title=Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. |journal=J. Cell Biol. |volume=145 |issue= 4 |pages= 899–910 |year= 1999 |pmid= 10330415 |doi=10.1083/jcb.145.4.899  | pmc=2133194 |display-authors=etal}}
*{{cite journal  | author=Li X, Tedder TF |title=CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization. |journal=Genomics |volume=55 |issue= 3 |pages= 345-7 |year= 1999 |pmid= 10049591 |doi= 10.1006/geno.1998.5653 }}
*{{cite journal  | vauthors=Tu L, Murphy PG, Li X, Tedder TF |title=L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1. |journal=J. Immunol. |volume=163 |issue= 9 |pages= 5070–8 |year= 1999 |pmid= 10528213 |doi=  }}
*{{cite journal  | author=Bistrup A, Bhakta S, Lee JK, ''et al.'' |title=Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. |journal=J. Cell Biol. |volume=145 |issue= 4 |pages= 899-910 |year= 1999 |pmid= 10330415 |doi=  }}
*{{cite journal  | vauthors=Torii T, Fukuta M, Habuchi O |title=Sulfation of sialyl N-acetyllactosamine oligosaccharides and fetuin oligosaccharides by keratan sulfate Gal-6-sulfotransferase. |journal=Glycobiology |volume=10 |issue= 2 |pages= 203–11 |year= 2000 |pmid= 10642612 |doi=10.1093/glycob/10.2.203 }}
*{{cite journal  | author=Tu L, Murphy PG, Li X, Tedder TF |title=L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1. |journal=J. Immunol. |volume=163 |issue= 9 |pages= 5070-8 |year= 1999 |pmid= 10528213 |doi=  }}
*{{cite journal  | vauthors=Li X, Tu L, Murphy PG |title=CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. |journal=J. Leukoc. Biol. |volume=69 |issue= 4 |pages= 565–74 |year= 2001 |pmid= 11310842 |doi=  |display-authors=etal}}
*{{cite journal  | author=Torii T, Fukuta M, Habuchi O |title=Sulfation of sialyl N-acetyllactosamine oligosaccharides and fetuin oligosaccharides by keratan sulfate Gal-6-sulfotransferase. |journal=Glycobiology |volume=10 |issue= 2 |pages= 203-11 |year= 2000 |pmid= 10642612 |doi=  }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Li X, Tu L, Murphy PG, ''et al.'' |title=CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. |journal=J. Leukoc. Biol. |volume=69 |issue= 4 |pages= 565-74 |year= 2001 |pmid= 11310842 |doi=  }}
*{{cite journal  | vauthors=Yamada T, Ohtake S, Sato M, Habuchi O |title=Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues. |journal=Biochem. J. |volume=384 |issue= Pt 3 |pages= 567–75 |year= 2005 |pmid= 15324304 |doi= 10.1042/BJ20040965 | pmc=1134142 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Yamada T, Ohtake S, Sato M, Habuchi O |title=Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues. |journal=Biochem. J. |volume=384 |issue= Pt 3 |pages= 567-75 |year= 2005 |pmid= 15324304 |doi= 10.1042/BJ20040965 }}
*{{cite journal  | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Liu J, Chau CH, Liu H |title=Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth. |journal=J. Cell Sci. |volume=119 |issue= Pt 5 |pages= 933–42 |year= 2006 |pmid= 16495484 |doi= 10.1242/jcs.02796 |display-authors=etal}}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | vauthors=Kitayama K, Hayashida Y, Nishida K, Akama TO |title=Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans. |journal=J. Biol. Chem. |volume=282 |issue= 41 |pages= 30085–96 |year= 2007 |pmid= 17690104 |doi= 10.1074/jbc.M703695200 }}
*{{cite journal  | author=Liu J, Chau CH, Liu H, ''et al.'' |title=Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth. |journal=J. Cell. Sci. |volume=119 |issue= Pt 5 |pages= 933-42 |year= 2006 |pmid= 16495484 |doi= 10.1242/jcs.02796 }}
*{{cite journal  | author=Kitayama K, Hayashida Y, Nishida K, Akama TO |title=Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans. |journal=J. Biol. Chem. |volume=282 |issue= 41 |pages= 30085-96 |year= 2007 |pmid= 17690104 |doi= 10.1074/jbc.M703695200 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 19:34, 8 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Carbohydrate sulfotransferase 1 is an enzyme that in humans is encoded by the CHST1 gene.[1][2][3]


References

  1. ↑ Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O (Jan 1998). "Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase". J Biol Chem. 272 (51): 32321–8. doi:10.1074/jbc.272.51.32321. PMID 9405439.
  2. ↑ Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ (Aug 1998). "Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization". Biochim Biophys Acta. 1407 (1): 92–7. doi:10.1016/s0925-4439(98)00028-3. PMID 9639683.
  3. ↑ "Entrez Gene: CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1".

External links

Further reading



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