CKAP4: Difference between revisions

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{{Infobox_gene}}
{{GNF_Protein_box
'''Cytoskeleton-associated protein 4''' is a [[protein]] that in humans is encoded by the ''CKAP4'' [[gene]].<ref name="pmid8314870">{{cite journal | vauthors = Schweizer A, Rohrer J, Jeno P, DeMaio A, Buchman TG, Hauri HP | title = A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein | journal = J Cell Sci | volume = 104 | issue =  3| pages = 685–94 |date=Jul 1993 | pmid = 8314870 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CKAP4 cytoskeleton-associated protein 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10970| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = Cytoskeleton-associated protein 4
| HGNCid = 16991
| Symbol = CKAP4
| AltSymbols =; p63; CLIMP-63; ERGIC-63; MGC99554
| OMIM = 
| ECnumber = 
| Homologene = 4970
| MGIid = 2444926
| GeneAtlas_image1 = PBB_GE_CKAP4_200998_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_CKAP4_200999_s_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process =  
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10970
    | Hs_Ensembl = ENSG00000136026
    | Hs_RefseqProtein = NP_006816
    | Hs_RefseqmRNA = NM_006825
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 105155933
    | Hs_GenLoc_end = 105165806
    | Hs_Uniprot = Q07065
    | Mm_EntrezGene = 216197
    | Mm_Ensembl = ENSMUSG00000046841
    | Mm_RefseqmRNA = XM_987365
    | Mm_RefseqProtein = XP_992459
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 83956104
    | Mm_GenLoc_end = 83963687
    | Mm_Uniprot = Q8BMK4
  }}
}}
'''Cytoskeleton-associated protein 4''', also known as '''CKAP4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CKAP4 cytoskeleton-associated protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10970| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CKAP4}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Mundy DI |title=Protein palmitoylation in membrane trafficking. |journal=Biochem. Soc. Trans. |volume=23 |issue= 3 |pages= 572-6 |year= 1996 |pmid= 8566419 |doi=  }}
*{{cite journal  | author=Mundy DI |title=Protein palmitoylation in membrane trafficking. |journal=Biochem. Soc. Trans. |volume=23 |issue= 3 |pages= 572–6 |year= 1996 |pmid= 8566419 |doi=  }}
*{{cite journal  | author=Mundy DI, Warren G |title=Mitosis and inhibition of intracellular transport stimulate palmitoylation of a 62-kD protein. |journal=J. Cell Biol. |volume=116 |issue= 1 |pages= 135-46 |year= 1992 |pmid= 1730740 |doi=  }}
*{{cite journal  | vauthors=Mundy DI, Warren G |title=Mitosis and inhibition of intracellular transport stimulate palmitoylation of a 62-kD protein. |journal=J. Cell Biol. |volume=116 |issue= 1 |pages= 135–46 |year= 1992 |pmid= 1730740 |doi=10.1083/jcb.116.1.135  | pmc=2289273 }}
*{{cite journal  | author=Schweizer A, Rohrer J, Slot JW, ''et al.'' |title=Reassessment of the subcellular localization of p63. |journal=J. Cell. Sci. |volume=108 ( Pt 6) |issue=  |pages= 2477-85 |year= 1995 |pmid= 7673362 |doi=  }}
*{{cite journal  | vauthors=Schweizer A, Rohrer J, Slot JW |title=Reassessment of the subcellular localization of p63. |journal=J. Cell Sci. |volume=108 |issue=  6|pages= 2477–85 |year= 1995 |pmid= 7673362 |doi=  |display-authors=etal}}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Schweizer A, Rohrer J, Jenö P, ''et al.'' |title=A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein. |journal=J. Cell. Sci. |volume=104 ( Pt 3) |issue=  |pages= 685-94 |year= 1993 |pmid= 8314870 |doi= }}
*{{cite journal  | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | vauthors=Klopfenstein DR, Klumperman J, Lustig A |title=Subdomain-specific localization of CLIMP-63 (p63) in the endoplasmic reticulum is mediated by its luminal alpha-helical segment. |journal=J. Cell Biol. |volume=153 |issue= 6 |pages= 1287–300 |year= 2001 |pmid= 11402071 |doi=10.1083/jcb.153.6.1287  | pmc=2192027 |display-authors=etal}}
*{{cite journal  | author=Klopfenstein DR, Klumperman J, Lustig A, ''et al.'' |title=Subdomain-specific localization of CLIMP-63 (p63) in the endoplasmic reticulum is mediated by its luminal alpha-helical segment. |journal=J. Cell Biol. |volume=153 |issue= 6 |pages= 1287-300 |year= 2001 |pmid= 11402071 |doi=  }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Razzaq TM, Bass R, Vines DJ |title=Functional regulation of tissue plasminogen activator on the surface of vascular smooth muscle cells by the type-II transmembrane protein p63 (CKAP4). |journal=J. Biol. Chem. |volume=278 |issue= 43 |pages= 42679–85 |year= 2004 |pmid= 12913003 |doi= 10.1074/jbc.M305695200 |display-authors=etal}}
*{{cite journal  | author=Razzaq TM, Bass R, Vines DJ, ''et al.'' |title=Functional regulation of tissue plasminogen activator on the surface of vascular smooth muscle cells by the type-II transmembrane protein p63 (CKAP4). |journal=J. Biol. Chem. |volume=278 |issue= 43 |pages= 42679-85 |year= 2004 |pmid= 12913003 |doi= 10.1074/jbc.M305695200 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Vedrenne C, Klopfenstein DR, Hauri HP |title=Phosphorylation controls CLIMP-63-mediated anchoring of the endoplasmic reticulum to microtubules. |journal=Mol. Biol. Cell |volume=16 |issue= 4 |pages= 1928–37 |year= 2005 |pmid= 15703217 |doi= 10.1091/mbc.E04-07-0554 | pmc=1073672 }}
*{{cite journal  | author=Vedrenne C, Klopfenstein DR, Hauri HP |title=Phosphorylation controls CLIMP-63-mediated anchoring of the endoplasmic reticulum to microtubules. |journal=Mol. Biol. Cell |volume=16 |issue= 4 |pages= 1928-37 |year= 2005 |pmid= 15703217 |doi= 10.1091/mbc.E04-07-0554 }}
*{{cite journal  | vauthors=Beretta C, Chiarelli A, Testoni B |title=Regulation of the cyclin-dependent kinase inhibitor p57Kip2 expression by p63. |journal=Cell Cycle |volume=4 |issue= 11 |pages= 1625–31 |year= 2007 |pmid= 16258268 |doi=10.4161/cc.4.11.2135 |display-authors=etal}}
*{{cite journal  | author=Beretta C, Chiarelli A, Testoni B, ''et al.'' |title=Regulation of the cyclin-dependent kinase inhibitor p57Kip2 expression by p63. |journal=Cell Cycle |volume=4 |issue= 11 |pages= 1625-31 |year= 2007 |pmid= 16258268 |doi= }}
*{{cite journal  | vauthors=Ribeiro-Silva A, Becker de Moura H, Ribeiro do Vale F, Zucoloto S |title=The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas. |journal=Int. J. Biol. Markers |volume=20 |issue= 4 |pages= 227–34 |year= 2006 |pmid= 16398404 |doi=  }}
*{{cite journal  | author=Ribeiro-Silva A, Becker de Moura H, Ribeiro do Vale F, Zucoloto S |title=The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas. |journal=Int. J. Biol. Markers |volume=20 |issue= 4 |pages= 227-34 |year= 2006 |pmid= 16398404 |doi=  }}
*{{cite journal  | vauthors=Gu X, Bäckman B, Coates PJ |title=Exclusion of p63 as a candidate gene for autosomal-dominant amelogenesis imperfecta. |journal=Acta Odontol. Scand. |volume=64 |issue= 2 |pages= 111–4 |year= 2006 |pmid= 16546853 |doi= 10.1080/00016350500443206 |display-authors=etal}}
*{{cite journal  | author=Gu X, Bäckman B, Coates PJ, ''et al.'' |title=Exclusion of p63 as a candidate gene for autosomal-dominant amelogenesis imperfecta. |journal=Acta Odontol. Scand. |volume=64 |issue= 2 |pages= 111-4 |year= 2006 |pmid= 16546853 |doi= 10.1080/00016350500443206 }}
*{{cite journal  | vauthors=Conrads TP, Tocci GM, Hood BL |title=CKAP4/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients. |journal=J. Biol. Chem. |volume=281 |issue= 49 |pages= 37836–43 |year= 2007 |pmid= 17030514 |doi= 10.1074/jbc.M604581200 |display-authors=etal}}
*{{cite journal  | author=Conrads TP, Tocci GM, Hood BL, ''et al.'' |title=CKAP4/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients. |journal=J. Biol. Chem. |volume=281 |issue= 49 |pages= 37836-43 |year= 2007 |pmid= 17030514 |doi= 10.1074/jbc.M604581200 }}
*{{cite journal  | vauthors=Troxell ML, Masek M, Sibley RK |title=Immunohistochemical staining of papillary breast lesions. |journal=Appl. Immunohistochem. Mol. Morphol. |volume=15 |issue= 2 |pages= 145–53 |year= 2007 |pmid= 17525625 |doi= 10.1097/01.pai.0000210420.45869.f4 }}
*{{cite journal  | author=Troxell ML, Masek M, Sibley RK |title=Immunohistochemical staining of papillary breast lesions. |journal=Appl. Immunohistochem. Mol. Morphol. |volume=15 |issue= 2 |pages= 145-53 |year= 2007 |pmid= 17525625 |doi= 10.1097/01.pai.0000210420.45869.f4 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 19:34, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cytoskeleton-associated protein 4 is a protein that in humans is encoded by the CKAP4 gene.[1][2]


References

  1. ↑ Schweizer A, Rohrer J, Jeno P, DeMaio A, Buchman TG, Hauri HP (Jul 1993). "A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein". J Cell Sci. 104 (3): 685–94. PMID 8314870.
  2. ↑ "Entrez Gene: CKAP4 cytoskeleton-associated protein 4".

External links

Further reading



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