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{{Infobox_gene}}
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
'''Kinectin''' is a [[protein]] that in humans is encoded by the ''KTN1'' [[gene]].<ref name="pmid9605849">{{cite journal | vauthors = Rao PN, Yu H, Hodge R, Pettenati MJ, Sheetz MP | title = Assignment of the human kinectin gene (KTN1), encoding a kinesin-binding protein, to chromosome 14 band q22.1 by in situ hybridization | journal = Cytogenet. Cell Genet. | volume = 79 | issue = 3-4 | pages = 196–7 | year = 1997 | pmid = 9605849 | pmc =  | doi = 10.1159/000134719 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KTN1 kinectin 1 (kinesin receptor)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3895| accessdate = }}</ref>
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Kinectin 1 (kinesin receptor)
| HGNCid = 6467
| Symbol = KTN1
| AltSymbols =; CG1; KIAA0004; KNT; MGC133337; MU-RMS-40.19
| OMIM = 600381
| ECnumber = 
| Homologene = 7397
| MGIid = 109153
| GeneAtlas_image1 = PBB_GE_KTN1_214709_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_KTN1_200914_x_at_tn.png
| GeneAtlas_image3 = PBB_GE_KTN1_200915_x_at_tn.png
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005789 |text = endoplasmic reticulum membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007018 |text = microtubule-based movement}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3895
    | Hs_Ensembl = ENSG00000126777
    | Hs_RefseqProtein = NP_001072989
    | Hs_RefseqmRNA = NM_001079521
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 55116777
    | Hs_GenLoc_end = 55221047
    | Hs_Uniprot = Q86UP2
    | Mm_EntrezGene = 16709
    | Mm_Ensembl = ENSMUSG00000021843
    | Mm_RefseqmRNA = NM_008477
    | Mm_RefseqProtein = NP_032503
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 14
    | Mm_GenLoc_start = 46571234
    | Mm_GenLoc_end = 46658434
    | Mm_Uniprot = Q61595
  }}
}}
'''Kinectin 1 (kinesin receptor)''', also known as '''KTN1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: KTN1 kinectin 1 (kinesin receptor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3895| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{PBB_Summary
| section_title =  
| summary_text = Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: KTN1 kinectin 1 (kinesin receptor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3895| accessdate = }}</ref>
}}


==References==
Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM]<ref name="entrez" />
{{reflist|2}}
 
==Further reading==
== Interactions ==
 
KTN1 has been shown to [[Protein-protein interaction|interact]] with [[EEF1D]],<ref name=pmid12773547>{{cite journal | vauthors = Ong LL, Er CP, Ho A, Aung MT, Yu H | title = Kinectin anchors the translation elongation factor-1 delta to the endoplasmic reticulum | journal = J. Biol. Chem. | volume = 278 | issue = 34 | pages = 32115–23  | date = Aug 2003 | pmid = 12773547 | doi = 10.1074/jbc.M210917200 }}</ref> [[RhoG]]<ref name=pmid11162552>{{cite journal | vauthors = Neudauer CL, Joberty G, Macara IG | title = PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10 | journal = Biochem. Biophys. Res. Commun. | volume = 280 | issue = 2 | pages = 541–7  | date = Jan 2001 | pmid = 11162552 | doi = 10.1006/bbrc.2000.4160 }}</ref><ref name=pmid11689693>{{cite journal | vauthors = Vignal E, Blangy A, Martin M, Gauthier-Rouvière C, Fort P | title = Kinectin is a key effector of RhoG microtubule-dependent cellular activity | journal = Mol. Cell. Biol. | volume = 21 | issue = 23 | pages = 8022–34  | date = Dec 2001 | pmid = 11689693 | pmc = 99969 | doi = 10.1128/MCB.21.23.8022-8034.2001 }}</ref> and [[RHOA]].<ref name=pmid11162552/><ref name=pmid11689693/><ref name=pmid12773565>{{cite journal | vauthors = Riento K, Guasch RM, Garg R, Jin B, Ridley AJ | title = RhoE binds to ROCK I and inhibits downstream signaling | journal = Mol. Cell. Biol. | volume = 23 | issue = 12 | pages = 4219–29  | date = Jun 2003 | pmid = 12773565 | pmc = 156133 | doi = 10.1128/MCB.23.12.4219-4229.2003 }}</ref><ref name=pmid8769096>{{cite journal | vauthors = Hotta K, Tanaka K, Mino A, Kohno H, Takai Y | title = Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor | journal = Biochem. Biophys. Res. Commun. | volume = 225 | issue = 1 | pages = 69–74  | date = Aug 1996 | pmid = 8769096 | doi = 10.1006/bbrc.1996.1132 }}</ref>
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S | title = Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 | journal = DNA Res. | volume = 1 | issue = 1 | pages = 27–35 | year = 1994 | pmid = 7584026 | doi = 10.1093/dnares/1.1.27 }}
| citations =
* {{cite journal | vauthors = Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S | title = Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement) | journal = DNA Res. | volume = 1 | issue = 1 | pages = 47–56 | year = 1994 | pmid = 7584028 | doi = 10.1093/dnares/1.1.47 }}
*{{cite journal | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27-35 |year= 1995 |pmid= 7584026 |doi= }}
* {{cite journal | vauthors = Fütterer A, Kruppa G, Krämer B, Lemke H, Krönke M | title = Molecular cloning and characterization of human kinectin | journal = Mol. Biol. Cell | volume = 6 | issue = 2 | pages = 161–70 | year = 1995 | pmid = 7787243 | pmc = 275826 | doi = 10.1091/mbc.6.2.161 }}
*{{cite journal | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47-56 |year= 1995 |pmid= 7584028 |doi= }}
* {{cite journal | vauthors = Yu H, Nicchitta CV, Kumar J, Becker M, Toyoshima I, Sheetz MP | title = Characterization of kinectin, a kinesin-binding protein: primary sequence and N-terminal topogenic signal analysis | journal = Mol. Biol. Cell | volume = 6 | issue = 2 | pages = 171–83 | year = 1995 | pmid = 7787244 | pmc = 275827 | doi = 10.1091/mbc.6.2.171 }}
*{{cite journal | author=Fütterer A, Kruppa G, Krämer B, ''et al.'' |title=Molecular cloning and characterization of human kinectin. |journal=Mol. Biol. Cell |volume=6 |issue= 2 |pages= 161-70 |year= 1995 |pmid= 7787243 |doi= }}
* {{cite journal | vauthors = Print CG, Leung E, Harrison JE, Watson JD, Krissansen GW | title = Cloning of a gene encoding a human leukocyte protein characterised by extensive heptad repeats | journal = Gene | volume = 144 | issue = 2 | pages = 221–8 | year = 1994 | pmid = 8039706 | doi = 10.1016/0378-1119(94)90381-6 }}
*{{cite journal | author=Yu H, Nicchitta CV, Kumar J, ''et al.'' |title=Characterization of kinectin, a kinesin-binding protein: primary sequence and N-terminal topogenic signal analysis. |journal=Mol. Biol. Cell |volume=6 |issue= 2 |pages= 171-83 |year= 1995 |pmid= 7787244 |doi= }}
* {{cite journal | vauthors = Print CG, Morris CM, Spurr NK, Rooke L, Krissansen GW | title = The CG-1 gene, a member of the kinectin and ES/130 family, maps to human chromosome band 14q22 | journal = Immunogenetics | volume = 43 | issue = 4 | pages = 227–9 | year = 1996 | pmid = 8575822 | doi = 10.1007/s002510050050 }}
*{{cite journal | author=Print CG, Leung E, Harrison JE, ''et al.'' |title=Cloning of a gene encoding a human leukocyte protein characterised by extensive heptad repeats. |journal=Gene |volume=144 |issue= 2 |pages= 221-8 |year= 1994 |pmid= 8039706 |doi= }}
* {{cite journal | vauthors = Hotta K, Tanaka K, Mino A, Kohno H, Takai Y | title = Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor | journal = Biochem. Biophys. Res. Commun. | volume = 225 | issue = 1 | pages = 69–74 | year = 1996 | pmid = 8769096 | doi = 10.1006/bbrc.1996.1132 }}
*{{cite journal | author=Print CG, Morris CM, Spurr NK, ''et al.'' |title=The CG-1 gene, a member of the kinectin and ES/130 family, maps to human chromosome band 14q22. |journal=Immunogenetics |volume=43 |issue= 4 |pages= 227-9 |year= 1996 |pmid= 8575822 |doi= }}
* {{cite journal | vauthors = Alberts AS, Bouquin N, Johnston LH, Treisman R | title = Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7 | journal = J. Biol. Chem. | volume = 273 | issue = 15 | pages = 8616–22 | year = 1998 | pmid = 9535835 | doi = 10.1074/jbc.273.15.8616 }}
*{{cite journal | author=Hotta K, Tanaka K, Mino A, ''et al.'' |title=Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor. |journal=Biochem. Biophys. Res. Commun. |volume=225 |issue= 1 |pages= 69-74 |year= 1996 |pmid= 8769096 |doi= 10.1006/bbrc.1996.1132 }}
* {{cite journal | vauthors = Vancoillie G, Lambert J, Mulder A, Koerten HK, Mommaas AM, Van Oostveldt P, Naeyaert JM | title = Kinesin and kinectin can associate with the melanosomal surface and form a link with microtubules in normal human melanocytes | journal = J. Invest. Dermatol. | volume = 114 | issue = 3 | pages = 421–9 | year = 2000 | pmid = 10692099 | doi = 10.1046/j.1523-1747.2000.00896.x }}
*{{cite journal | author=Alberts AS, Bouquin N, Johnston LH, Treisman R |title=Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. |journal=J. Biol. Chem. |volume=273 |issue= 15 |pages= 8616-22 |year= 1998 |pmid= 9535835 |doi= }}
* {{cite journal | vauthors = Salassidis K, Bruch J, Zitzelsberger H, Lengfelder E, Kellerer AM, Bauchinger M | title = Translocation t(10;14)(q11.2:q22.1) fusing the kinetin to the RET gene creates a novel rearranged form (PTC8) of the RET proto-oncogene in radiation-induced childhood papillary thyroid carcinoma | journal = Cancer Res. | volume = 60 | issue = 11 | pages = 2786–9 | year = 2000 | pmid = 10850414 | doi = }}
*{{cite journal | author=Rao PN, Yu H, Hodge R, ''et al.'' |title=Assignment of the human kinectin gene (KTN1), encoding a kinesin-binding protein, to chromosome 14 band q22.1 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=79 |issue= 3-4 |pages= 196-7 |year= 1998 |pmid= 9605849 |doi= }}
* {{cite journal | vauthors = Ong LL, Lim AP, Er CP, Kuznetsov SA, Yu H | title = Kinectin-kinesin binding domains and their effects on organelle motility | journal = J. Biol. Chem. | volume = 275 | issue = 42 | pages = 32854–60 | year = 2000 | pmid = 10913441 | doi = 10.1074/jbc.M005650200 }}
*{{cite journal | author=Vancoillie G, Lambert J, Mulder A, ''et al.'' |title=Kinesin and kinectin can associate with the melanosomal surface and form a link with microtubules in normal human melanocytes. |journal=J. Invest. Dermatol. |volume=114 |issue= 3 |pages= 421-9 |year= 2000 |pmid= 10692099 |doi= 10.1046/j.1523-1747.2000.00896.x }}
* {{cite journal | vauthors = Harrington JJ, Sherf B, Rundlett S, Jackson PD, Perry R, Cain S, Leventhal C, Thornton M, Ramachandran R, Whittington J, Lerner L, Costanzo D, McElligott K, Boozer S, Mays R, Smith E, Veloso N, Klika A, Hess J, Cothren K, Lo K, Offenbacher J, Danzig J, Ducar M | title = Creation of genome-wide protein expression libraries using random activation of gene expression | journal = Nat. Biotechnol. | volume = 19 | issue = 5 | pages = 440–5 | year = 2001 | pmid = 11329013 | doi = 10.1038/88107 }}
*{{cite journal | author=Salassidis K, Bruch J, Zitzelsberger H, ''et al.'' |title=Translocation t(10;14)(q11.2:q22.1) fusing the kinetin to the RET gene creates a novel rearranged form (PTC8) of the RET proto-oncogene in radiation-induced childhood papillary thyroid carcinoma. |journal=Cancer Res. |volume=60 |issue= 11 |pages= 2786-9 |year= 2000 |pmid= 10850414 |doi= }}
* {{cite journal | vauthors = Vignal E, Blangy A, Martin M, Gauthier-Rouvière C, Fort P | title = Kinectin is a key effector of RhoG microtubule-dependent cellular activity | journal = Mol. Cell. Biol. | volume = 21 | issue = 23 | pages = 8022–34 | year = 2001 | pmid = 11689693 | pmc = 99969 | doi = 10.1128/MCB.21.23.8022-8034.2001 }}
*{{cite journal | author=Ong LL, Lim AP, Er CP, ''et al.'' |title=Kinectin-kinesin binding domains and their effects on organelle motility. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32854-60 |year= 2000 |pmid= 10913441 |doi= 10.1074/jbc.M005650200 }}
* {{cite journal | vauthors = Tran H, Pankov R, Tran SD, Hampton B, Burgess WH, Yamada KM | title = Integrin clustering induces kinectin accumulation | journal = J. Cell Sci. | volume = 115 | issue = Pt 10 | pages = 2031–40 | year = 2002 | pmid = 11973345 | doi = }}
*{{cite journal | author=Harrington JJ, Sherf B, Rundlett S, ''et al.'' |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440-5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 }}
* {{cite journal | vauthors = Ong LL, Er CP, Ho A, Aung MT, Yu H | title = Kinectin anchors the translation elongation factor-1 delta to the endoplasmic reticulum | journal = J. Biol. Chem. | volume = 278 | issue = 34 | pages = 32115–23 | year = 2003 | pmid = 12773547 | doi = 10.1074/jbc.M210917200 }}
*{{cite journal | author=Vignal E, Blangy A, Martin M, ''et al.'' |title=Kinectin is a key effector of RhoG microtubule-dependent cellular activity. |journal=Mol. Cell. Biol. |volume=21 |issue= 23 |pages= 8022-34 |year= 2001 |pmid= 11689693 |doi= 10.1128/MCB.21.23.8022-8034.2001 }}
* {{cite journal | vauthors = Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G | title = A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | journal = Nat. Cell Biol. | volume = 6 | issue = 2 | pages = 97–105 | year = 2004 | pmid = 14743216 | doi = 10.1038/ncb1086 }}
*{{cite journal | author=Tran H, Pankov R, Tran SD, ''et al.'' |title=Integrin clustering induces kinectin accumulation. |journal=J. Cell. Sci. |volume=115 |issue= Pt 10 |pages= 2031-40 |year= 2003 |pmid= 11973345 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Heilig R, Eckenberg R, Petit JL, ''et al.'' |title=The DNA sequence and analysis of human chromosome 14. |journal=Nature |volume=421 |issue= 6923 |pages= 601-7 |year= 2003 |pmid= 12508121 |doi= 10.1038/nature01348 }}
*{{cite journal  | author=Ong LL, Er CP, Ho A, ''et al.'' |title=Kinectin anchors the translation elongation factor-1 delta to the endoplasmic reticulum. |journal=J. Biol. Chem. |volume=278 |issue= 34 |pages= 32115-23 |year= 2003 |pmid= 12773547 |doi= 10.1074/jbc.M210917200 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
 
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Latest revision as of 20:12, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Kinectin is a protein that in humans is encoded by the KTN1 gene.[1][2]

Function

Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM][2]

Interactions

KTN1 has been shown to interact with EEF1D,[3] RhoG[4][5] and RHOA.[4][5][6][7]

References

  1. ↑ Rao PN, Yu H, Hodge R, Pettenati MJ, Sheetz MP (1997). "Assignment of the human kinectin gene (KTN1), encoding a kinesin-binding protein, to chromosome 14 band q22.1 by in situ hybridization". Cytogenet. Cell Genet. 79 (3–4): 196–7. doi:10.1159/000134719. PMID 9605849.
  2. ↑ 2.0 2.1 "Entrez Gene: KTN1 kinectin 1 (kinesin receptor)".
  3. ↑ Ong LL, Er CP, Ho A, Aung MT, Yu H (Aug 2003). "Kinectin anchors the translation elongation factor-1 delta to the endoplasmic reticulum". J. Biol. Chem. 278 (34): 32115–23. doi:10.1074/jbc.M210917200. PMID 12773547.
  4. ↑ 4.0 4.1 Neudauer CL, Joberty G, Macara IG (Jan 2001). "PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10". Biochem. Biophys. Res. Commun. 280 (2): 541–7. doi:10.1006/bbrc.2000.4160. PMID 11162552.
  5. ↑ 5.0 5.1 Vignal E, Blangy A, Martin M, Gauthier-Rouvière C, Fort P (Dec 2001). "Kinectin is a key effector of RhoG microtubule-dependent cellular activity". Mol. Cell. Biol. 21 (23): 8022–34. doi:10.1128/MCB.21.23.8022-8034.2001. PMC 99969. PMID 11689693.
  6. ↑ Riento K, Guasch RM, Garg R, Jin B, Ridley AJ (Jun 2003). "RhoE binds to ROCK I and inhibits downstream signaling". Mol. Cell. Biol. 23 (12): 4219–29. doi:10.1128/MCB.23.12.4219-4229.2003. PMC 156133. PMID 12773565.
  7. ↑ Hotta K, Tanaka K, Mino A, Kohno H, Takai Y (Aug 1996). "Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor". Biochem. Biophys. Res. Commun. 225 (1): 69–74. doi:10.1006/bbrc.1996.1132. PMID 8769096.

Further reading

  • Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
  • Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Res. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.
  • Fütterer A, Kruppa G, Krämer B, Lemke H, Krönke M (1995). "Molecular cloning and characterization of human kinectin". Mol. Biol. Cell. 6 (2): 161–70. doi:10.1091/mbc.6.2.161. PMC 275826. PMID 7787243.
  • Yu H, Nicchitta CV, Kumar J, Becker M, Toyoshima I, Sheetz MP (1995). "Characterization of kinectin, a kinesin-binding protein: primary sequence and N-terminal topogenic signal analysis". Mol. Biol. Cell. 6 (2): 171–83. doi:10.1091/mbc.6.2.171. PMC 275827. PMID 7787244.
  • Print CG, Leung E, Harrison JE, Watson JD, Krissansen GW (1994). "Cloning of a gene encoding a human leukocyte protein characterised by extensive heptad repeats". Gene. 144 (2): 221–8. doi:10.1016/0378-1119(94)90381-6. PMID 8039706.
  • Print CG, Morris CM, Spurr NK, Rooke L, Krissansen GW (1996). "The CG-1 gene, a member of the kinectin and ES/130 family, maps to human chromosome band 14q22". Immunogenetics. 43 (4): 227–9. doi:10.1007/s002510050050. PMID 8575822.
  • Hotta K, Tanaka K, Mino A, Kohno H, Takai Y (1996). "Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor". Biochem. Biophys. Res. Commun. 225 (1): 69–74. doi:10.1006/bbrc.1996.1132. PMID 8769096.
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