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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Amyloid beta A4 precursor protein-binding family A member 2''' is a [[protein]] that in humans is encoded by the ''APBA2'' [[gene]].<ref name="pmid8955346">{{cite journal | vauthors = McLoughlin DM, Miller CC | title = The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system | journal = FEBS Lett | volume = 397 | issue = 2–3 | pages = 197–200 | date = January 1997 | pmid = 8955346 | pmc =  | doi = 10.1016/S0014-5793(96)01128-3 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=321| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image = PBB_Protein_APBA2_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1u39.
| PDB = {{PDB2|1u39}}, {{PDB2|1y7n}}
| Name = Amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
| HGNCid = 579
| Symbol = APBA2
| AltSymbols =; D15S1518E; HsT16821; LIN-10; MGC99508; MGC:14091; MINT2; X11L
| OMIM = 602712
| ECnumber = 
| Homologene = 4021
| MGIid = 1261791
| GeneAtlas_image1 = PBB_GE_APBA2_209871_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_APBA2_209870_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component =
| Process = {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 321
    | Hs_Ensembl = ENSG00000034053
    | Hs_RefseqProtein = NP_005494
    | Hs_RefseqmRNA = NM_005503
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 15
    | Hs_GenLoc_start = 27001141
    | Hs_GenLoc_end = 27197806
    | Hs_Uniprot = Q99767
    | Mm_EntrezGene = 11784
    | Mm_Ensembl = ENSMUSG00000030519
    | Mm_RefseqmRNA = NM_007461
    | Mm_RefseqProtein = NP_031487
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 64380656
    | Mm_GenLoc_end = 64632828
    | Mm_Uniprot = Q9Z316
  }}
}}
'''Amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)''', also known as '''APBA2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=321| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.<ref name="entrez">{{cite web | title = Entrez Gene: APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=321| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
APBA2 has been shown to [[Protein-protein interaction|interact]] with [[CLSTN1]],<ref name=pmid12972431>{{cite journal | vauthors = Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T | title = Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism | journal = J. Biol. Chem. | volume = 278 | issue = 49 | pages = 49448–58 | date = December 2003 | pmid = 12972431 | doi = 10.1074/jbc.M306024200 }}</ref><ref name=pmid15037614>{{cite journal | vauthors = Araki Y, Miyagi N, Kato N, Yoshida T, Wada S, Nishimura M, Komano H, Yamamoto T, De Strooper B, Yamamoto K, Suzuki T | title = Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation | journal = J. Biol. Chem. | volume = 279 | issue = 23 | pages = 24343–54 | date = June 2004 | pmid = 15037614 | doi = 10.1074/jbc.M401925200 }}</ref> [[RELA]]<ref name=pmid10777610>{{cite journal | vauthors = Tomita S, Fujita T, Kirino Y, Suzuki T | title = PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein | journal = J. Biol. Chem. | volume = 275 | issue = 17 | pages = 13056–60 | date = April 2000 | pmid = 10777610 | doi = 10.1074/jbc.C000019200 }}</ref> and [[Amyloid precursor protein]].<ref name=pmid12972431/><ref name=pmid12196555>{{cite journal | vauthors = Biederer T, Cao X, Südhof TC, Liu X | title = Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms | journal = J. Neurosci. | volume = 22 | issue = 17 | pages = 7340–51 | date = September 2002 | pmid = 12196555 }}</ref><ref name=pmid9890987>{{cite journal | vauthors = Tomita S, Ozaki T, Taru H, Oguchi S, Takeda S, Yagi Y, Sakiyama S, Kirino Y, Suzuki T | title = Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein | journal = J. Biol. Chem. | volume = 274 | issue = 4 | pages = 2243–54 | date = January 1999 | pmid = 9890987 | doi = 10.1074/jbc.274.4.2243 }}</ref>
 
== References ==
{{reflist}}
 
==External links==
* {{UCSC gene info|APBA2}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = van der Geer P, Pawson T | title = The PTB domain: a new protein module implicated in signal transduction | journal = Trends Biochem. Sci. | volume = 20 | issue = 7 | pages = 277–80 | year = 1995 | pmid = 7545337 | doi = 10.1016/S0968-0004(00)89043-X }}
| citations =
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Anal. Biochem. | volume = 236 | issue = 1 | pages = 107–13 | year = 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
*{{cite journal | author=van der Geer P, Pawson T |title=The PTB domain: a new protein module implicated in signal transduction. |journal=Trends Biochem. Sci. |volume=20 |issue= 7 |pages= 277-80 |year= 1995 |pmid= 7545337 |doi= }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Res. | volume = 7 | issue = 4 | pages = 353–8 | year = 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Okamoto M, Südhof TC | title = Mints, Munc18-interacting proteins in synaptic vesicle exocytosis | journal = J. Biol. Chem. | volume = 272 | issue = 50 | pages = 31459–64 | year = 1998 | pmid = 9395480 | doi = 10.1074/jbc.272.50.31459 }}
*{{cite journal | author=McLoughlin DM, Miller CC |title=The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system. |journal=FEBS Lett. |volume=397 |issue= 2-3 |pages= 197-200 |year= 1997 |pmid= 8955346 |doi= }}
* {{cite journal | vauthors = Blanco G, Irving NG, Brown SD, Miller CC, McLoughlin DM | title = Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein | journal = Mamm. Genome | volume = 9 | issue = 6 | pages = 473–5 | year = 1998 | pmid = 9585438 | doi = 10.1007/s003359900800 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
* {{cite journal | vauthors = Borg JP, Yang Y, De Taddéo-Borg M, Margolis B, Turner RS | title = The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion | journal = J. Biol. Chem. | volume = 273 | issue = 24 | pages = 14761–6 | year = 1998 | pmid = 9614075 | doi = 10.1074/jbc.273.24.14761 }}
*{{cite journal | author=Okamoto M, Südhof TC |title=Mints, Munc18-interacting proteins in synaptic vesicle exocytosis. |journal=J. Biol. Chem. |volume=272 |issue= 50 |pages= 31459-64 |year= 1998 |pmid= 9395480 |doi=  }}
* {{cite journal | vauthors = Borg JP, Straight SW, Kaech SM, de Taddéo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B | title = Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting | journal = J. Biol. Chem. | volume = 273 | issue = 48 | pages = 31633–6 | year = 1998 | pmid = 9822620 | doi = 10.1074/jbc.273.48.31633 }}
*{{cite journal  | author=Blanco G, Irving NG, Brown SD, ''et al.'' |title=Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein. |journal=Mamm. Genome |volume=9 |issue= 6 |pages= 473-5 |year= 1998 |pmid= 9585438 |doi= }}
* {{cite journal | vauthors = Okamoto M, Südhof TC | title = Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2 | journal = Eur. J. Cell Biol. | volume = 77 | issue = 3 | pages = 161–5 | year = 1999 | pmid = 9860131 | doi = 10.1016/s0171-9335(98)80103-9 }}
*{{cite journal | author=Borg JP, Yang Y, De Taddéo-Borg M, ''et al.'' |title=The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. |journal=J. Biol. Chem. |volume=273 |issue= 24 |pages= 14761-6 |year= 1998 |pmid= 9614075 |doi= }}
* {{cite journal | vauthors = Tomita S, Ozaki T, Taru H, Oguchi S, Takeda S, Yagi Y, Sakiyama S, Kirino Y, Suzuki T | title = Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein | journal = J. Biol. Chem. | volume = 274 | issue = 4 | pages = 2243–54 | year = 1999 | pmid = 9890987 | doi = 10.1074/jbc.274.4.2243 }}
*{{cite journal | author=Borg JP, Straight SW, Kaech SM, ''et al.'' |title=Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting. |journal=J. Biol. Chem. |volume=273 |issue= 48 |pages= 31633-6 |year= 1998 |pmid= 9822620 |doi= }}
* {{cite journal | vauthors = McLoughlin DM, Irving NG, Brownlees J, Brion JP, Leroy K, Miller CC | title = Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease | journal = Eur. J. Neurosci. | volume = 11 | issue = 6 | pages = 1988–94 | year = 1999 | pmid = 10336668 | doi = 10.1046/j.1460-9568.1999.00610.x }}
*{{cite journal | author=Okamoto M, Südhof TC |title=Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2. |journal=Eur. J. Cell Biol. |volume=77 |issue= 3 |pages= 161-5 |year= 1999 |pmid= 9860131 |doi= }}
* {{cite journal | vauthors = Tomita S, Fujita T, Kirino Y, Suzuki T | title = PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein | journal = J. Biol. Chem. | volume = 275 | issue = 17 | pages = 13056–60 | year = 2000 | pmid = 10777610 | doi = 10.1074/jbc.C000019200 }}
*{{cite journal | author=Tomita S, Ozaki T, Taru H, ''et al.'' |title=Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein. |journal=J. Biol. Chem. |volume=274 |issue= 4 |pages= 2243-54 |year= 1999 |pmid= 9890987 |doi= }}
* {{cite journal | vauthors = Gotthardt M, Trommsdorff M, Nevitt MF, Shelton J, Richardson JA, Stockinger W, Nimpf J, Herz J | title = Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction | journal = J. Biol. Chem. | volume = 275 | issue = 33 | pages = 25616–24 | year = 2000 | pmid = 10827173 | doi = 10.1074/jbc.M000955200 }}
*{{cite journal | author=McLoughlin DM, Irving NG, Brownlees J, ''et al.'' |title=Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease. |journal=Eur. J. Neurosci. |volume=11 |issue= 6 |pages= 1988-94 |year= 1999 |pmid= 10336668 |doi= }}
* {{cite journal | vauthors = Lee DS, Tomita S, Kirino Y, Suzuki T | title = Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein | journal = J. Biol. Chem. | volume = 275 | issue = 30 | pages = 23134–8 | year = 2000 | pmid = 10833507 | doi = 10.1074/jbc.C000302200 }}
*{{cite journal | author=Tomita S, Fujita T, Kirino Y, Suzuki T |title=PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein. |journal=J. Biol. Chem. |volume=275 |issue= 17 |pages= 13056-60 |year= 2000 |pmid= 10777610 |doi= }}
* {{cite journal | vauthors = Biederer T, Südhof TC | title = Mints as adaptors. Direct binding to neurexins and recruitment of munc18 | journal = J. Biol. Chem. | volume = 275 | issue = 51 | pages = 39803–6 | year = 2001 | pmid = 11036064 | doi = 10.1074/jbc.C000656200 }}
*{{cite journal | author=Gotthardt M, Trommsdorff M, Nevitt MF, ''et al.'' |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616-24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200 }}
* {{cite journal | vauthors = Lau KF, McLoughlin DM, Standen C, Miller CC | title = X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains | journal = Mol. Cell. Neurosci. | volume = 16 | issue = 5 | pages = 557–65 | year = 2001 | pmid = 11083918 | doi = 10.1006/mcne.2000.0898 }}
*{{cite journal | author=Lee DS, Tomita S, Kirino Y, Suzuki T |title=Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein. |journal=J. Biol. Chem. |volume=275 |issue= 30 |pages= 23134-8 |year= 2000 |pmid= 10833507 |doi= 10.1074/jbc.C000302200 }}
* {{cite journal | vauthors = Sutcliffe JS, Han MK, Amin T, Kesterson RA, Nurmi EL | title = Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures | journal = BMC Genomics | volume = 4 | pages = 15 | year = 2003 | pmid = 12720574 | pmc = 156605 | doi = 10.1186/1471-2164-4-15 }}
*{{cite journal | author=Biederer T, Südhof TC |title=Mints as adaptors. Direct binding to neurexins and recruitment of munc18. |journal=J. Biol. Chem. |volume=275 |issue= 51 |pages= 39803-6 |year= 2001 |pmid= 11036064 |doi= 10.1074/jbc.C000656200 }}
* {{cite journal | vauthors = Sumioka A, Imoto S, Martins RN, Kirino Y, Suzuki T | title = XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanisms | journal = Biochem. J. | volume = 374 | issue = Pt 1 | pages = 261–8 | year = 2003 | pmid = 12780348 | pmc = 1223589 | doi = 10.1042/BJ20030489 }}
*{{cite journal | author=Lau KF, McLoughlin DM, Standen C, Miller CC |title=X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains. |journal=Mol. Cell. Neurosci. |volume=16 |issue= 5 |pages= 557-65 |year= 2001 |pmid= 11083918 |doi= 10.1006/mcne.2000.0898 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Sutcliffe JS, Han MK, Amin T, ''et al.'' |title=Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures. |journal=BMC Genomics |volume=4 |issue= 1 |pages= 15 |year= 2003 |pmid= 12720574 |doi= 10.1186/1471-2164-4-15 }}
*{{cite journal  | author=Sumioka A, Imoto S, Martins RN, ''et al.'' |title=XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanisms. |journal=Biochem. J. |volume=374 |issue= Pt 1 |pages= 261-8 |year= 2003 |pmid= 12780348 |doi= 10.1042/BJ20030489 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{PDB Gallery|geneid=321}}
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{{gene-15-stub}}

Latest revision as of 18:07, 29 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Amyloid beta A4 precursor protein-binding family A member 2 is a protein that in humans is encoded by the APBA2 gene.[1][2]

Function

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.[2]

Interactions

APBA2 has been shown to interact with CLSTN1,[3][4] RELA[5] and Amyloid precursor protein.[3][6][7]

References

  1. ↑ McLoughlin DM, Miller CC (January 1997). "The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system". FEBS Lett. 397 (2–3): 197–200. doi:10.1016/S0014-5793(96)01128-3. PMID 8955346.
  2. ↑ 2.0 2.1 "Entrez Gene: APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)".
  3. ↑ 3.0 3.1 Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T (December 2003). "Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism". J. Biol. Chem. 278 (49): 49448–58. doi:10.1074/jbc.M306024200. PMID 12972431.
  4. ↑ Araki Y, Miyagi N, Kato N, Yoshida T, Wada S, Nishimura M, Komano H, Yamamoto T, De Strooper B, Yamamoto K, Suzuki T (June 2004). "Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation". J. Biol. Chem. 279 (23): 24343–54. doi:10.1074/jbc.M401925200. PMID 15037614.
  5. ↑ Tomita S, Fujita T, Kirino Y, Suzuki T (April 2000). "PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein". J. Biol. Chem. 275 (17): 13056–60. doi:10.1074/jbc.C000019200. PMID 10777610.
  6. ↑ Biederer T, Cao X, Südhof TC, Liu X (September 2002). "Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms". J. Neurosci. 22 (17): 7340–51. PMID 12196555.
  7. ↑ Tomita S, Ozaki T, Taru H, Oguchi S, Takeda S, Yagi Y, Sakiyama S, Kirino Y, Suzuki T (January 1999). "Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein". J. Biol. Chem. 274 (4): 2243–54. doi:10.1074/jbc.274.4.2243. PMID 9890987.

External links

Further reading


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