Metallothionein 1G: Difference between revisions

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Revision as of 21:34, 4 September 2017

Metallothionein-1G is a protein that in humans is encoded by the MT1G gene.^[1]^[2]^[3]

References

↑ Foster R, Jahroudi N, Varshney U, Gedamu L (Sep 1988). "Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals". J Biol Chem. 263 (23): 11528–35. PMID 3403543.
↑ Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.
↑ "Entrez Gene: MT1G metallothionein 1G".

West AK, Stallings R, Hildebrand CE, et al. (1991). "Human metallothionein genes: structure of the functional locus at 16q13". Genomics. 8 (3): 513–8. doi:10.1016/0888-7543(90)90038-V. PMID 2286373.
Gedamu L, Varshney U, Jahroudi N, et al. (1987). "Structure and expression of the human metallothionein genes". Experientia Suppl. 52: 361–72. doi:10.1007/978-3-0348-6784-9_34. PMID 2444457.
Varshney U, Jahroudi N, Foster R, Gedamu L (1987). "Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids". Mol. Cell. Biol. 6 (1): 26–37. PMC 367480. PMID 3023827.
Pauwels M, van Weyenbergh J, Soumillion A, et al. (1994). "Induction by zinc of specific metallothionein isoforms in human monocytes". Eur. J. Biochem. 220 (1): 105–10. doi:10.1111/j.1432-1033.1994.tb18603.x. PMID 8119276.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.
Huang Y, de la Chapelle A, Pellegata NS (2003). "Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma". Int. J. Cancer. 104 (6): 735–44. doi:10.1002/ijc.11006. PMID 12640681.
Cui YP, Wang JB, Zhang XY, et al. (2003). "Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene". World J. Gastroenterol. 9 (9): 1892–6. PMID 12970870.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Joshi B, Ordonez-Ercan D, Dasgupta P, Chellappan S (2005). "Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors". Oncogene. 24 (13): 2204–17. doi:10.1038/sj.onc.1208206. PMID 15735762.
Sun NN, Fastje CD, Wong SS, et al. (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line". Toxicology and industrial health. 19 (7–10): 157–63. doi:10.1191/0748233703th185oa. PMID 15747776.
Pope SN, Lee IR (2005). "Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem. Mol. Biol. 94 (1–3): 203–8. doi:10.1016/j.jsbmb.2005.01.007. PMID 15862967.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[pmid3403543-1] Foster R, Jahroudi N, Varshney U, Gedamu L (Sep 1988). "Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals". J Biol Chem. 263 (23): 11528–35. PMID 3403543.

[pmid6089206-2] Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.

[entrez-3] "Entrez Gene: MT1G metallothionein 1G".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=March 2014}}
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+'''Metallothionein-1G''' is a [[protein]] that in humans is encoded by the ''MT1G'' [[gene]].<ref name="pmid3403543">{{cite journal |vauthors=Foster R, Jahroudi N, Varshney U, Gedamu L | title = Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals | journal = J Biol Chem | volume = 263 | issue = 23 | pages = 11528–35 |date=Sep 1988 | pmid = 3403543 | pmc =  | doi =  }}</ref><ref name="pmid6089206">{{cite journal |vauthors=Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB | title = Human metallothionein genes are clustered on chromosome 16 | journal = Proc Natl Acad Sci U S A | volume = 81 | issue = 17 | pages = 5494–8 |date=Oct 1984 | pmid = 6089206 | pmc = 391732 | doi =10.1073/pnas.81.17.5494  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MT1G metallothionein 1G| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4495| accessdate = }}</ref>
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- | image = PBB_Protein_MT1G_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1mhu.
- | PDB = {{PDB2|1mhu}}, {{PDB2|1mrb}}, {{PDB2|1mrt}}, {{PDB2|2mhu}}
- | Name = Metallothionein 1G
- | HGNCid = 7399
- | Symbol = MT1G
- | AltSymbols =; MT1; MGC12386; MT1K
- | OMIM = 156353
- | ECnumber =
- | Homologene = 87857
- | MGIid =
-  | GeneAtlas_image1 = PBB_GE_MT1G_204745_x_at_tn.png
-  | Function = {{GNF_GO|id=GO:0005507 |text = copper ion binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046870 |text = cadmium ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component =
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 4495
-    | Hs_Ensembl = ENSG00000125144
-    | Hs_RefseqProtein = NP_005941
-    | Hs_RefseqmRNA = NM_005950
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 16
-    | Hs_GenLoc_start = 55258149
-    | Hs_GenLoc_end = 55259478
-    | Hs_Uniprot = P80295
-    | Mm_EntrezGene =
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-'''Metallothionein 1G''', also known as '''MT1G''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MT1G metallothionein 1G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4495| accessdate = }}</ref>
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@@ Line 55: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=West AK, Stallings R, Hildebrand CE, ''et al.'' |title=Human metallothionein genes: structure of the functional locus at 16q13. |journal=Genomics |volume=8 |issue= 3 |pages= 513-8 |year= 1991 |pmid= 2286373 |doi=  }}
+*{{cite journal   |vauthors=West AK, Stallings R, Hildebrand CE, etal |title=Human metallothionein genes: structure of the functional locus at 16q13. |journal=Genomics |volume=8 |issue= 3 |pages= 513–8 |year= 1991 |pmid= 2286373 |doi=10.1016/0888-7543(90)90038-V  }}
-*{{cite journal  | author=Gedamu L, Varshney U, Jahroudi N, ''et al.'' |title=Structure and expression of the human metallothionein genes. |journal=Experientia Suppl. |volume=52 |issue=  |pages= 361-72 |year= 1987 |pmid= 2444457 |doi=  }}
+*{{cite journal   |vauthors=Gedamu L, Varshney U, Jahroudi N, etal |title=Structure and expression of the human metallothionein genes. |journal=Experientia Suppl. |volume=52 |issue=  |pages= 361–72 |year= 1987 |pmid= 2444457 |doi=  10.1007/978-3-0348-6784-9_34}}
-*{{cite journal  | author=Varshney U, Jahroudi N, Foster R, Gedamu L |title=Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids. |journal=Mol. Cell. Biol. |volume=6 |issue= 1 |pages= 26-37 |year= 1987 |pmid= 3023827 |doi=  }}
+*{{cite journal  |vauthors=Varshney U, Jahroudi N, Foster R, Gedamu L |title=Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids. |journal=Mol. Cell. Biol. |volume=6 |issue= 1 |pages= 26–37 |year= 1987 |pmid= 3023827 |doi=  | pmc=367480  }}
-*{{cite journal  | author=Foster R, Jahroudi N, Varshney U, Gedamu L |title=Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals. |journal=J. Biol. Chem. |volume=263 |issue= 23 |pages= 11528-35 |year= 1988 |pmid= 3403543 |doi=  }}
+*{{cite journal   |vauthors=Pauwels M, van Weyenbergh J, Soumillion A, etal |title=Induction by zinc of specific metallothionein isoforms in human monocytes. |journal=Eur. J. Biochem. |volume=220 |issue= 1 |pages= 105–10 |year= 1994 |pmid= 8119276 |doi=10.1111/j.1432-1033.1994.tb18603.x  }}
-*{{cite journal  | author=Karin M, Eddy RL, Henry WM, ''et al.'' |title=Human metallothionein genes are clustered on chromosome 16. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 17 |pages= 5494-8 |year= 1984 |pmid= 6089206 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Pauwels M, van Weyenbergh J, Soumillion A, ''et al.'' |title=Induction by zinc of specific metallothionein isoforms in human monocytes. |journal=Eur. J. Biochem. |volume=220 |issue= 1 |pages= 105-10 |year= 1994 |pmid= 8119276 |doi=  }}
+*{{cite journal   |vauthors=Izmailova E, Bertley FM, Huang Q, etal |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191–7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  |vauthors=Huang Y, de la Chapelle A, Pellegata NS |title=Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. |journal=Int. J. Cancer |volume=104 |issue= 6 |pages= 735–44 |year= 2003 |pmid= 12640681 |doi= 10.1002/ijc.11006 }}
-*{{cite journal  | author=Izmailova E, Bertley FM, Huang Q, ''et al.'' |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191-7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }}
+*{{cite journal   |vauthors=Cui YP, Wang JB, Zhang XY, etal |title=Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene. |journal=World J. Gastroenterol. |volume=9 |issue= 9 |pages= 1892–6 |year= 2003 |pmid= 12970870 |doi=  }}
-*{{cite journal  | author=Huang Y, de la Chapelle A, Pellegata NS |title=Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. |journal=Int. J. Cancer |volume=104 |issue= 6 |pages= 735-44 |year= 2003 |pmid= 12640681 |doi= 10.1002/ijc.11006 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Cui YP, Wang JB, Zhang XY, ''et al.'' |title=Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene. |journal=World J. Gastroenterol. |volume=9 |issue= 9 |pages= 1892-6 |year= 2003 |pmid= 12970870 |doi=  }}
+*{{cite journal  |vauthors=Joshi B, Ordonez-Ercan D, Dasgupta P, Chellappan S |title=Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors. |journal=Oncogene |volume=24 |issue= 13 |pages= 2204–17 |year= 2005 |pmid= 15735762 |doi= 10.1038/sj.onc.1208206 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Sun NN, Fastje CD, Wong SS, etal |title=Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line. |journal=Toxicology and industrial health |volume=19 |issue= 7-10 |pages= 157–63 |year= 2005 |pmid= 15747776 |doi=10.1191/0748233703th185oa  }}
-*{{cite journal  | author=Joshi B, Ordonez-Ercan D, Dasgupta P, Chellappan S |title=Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors. |journal=Oncogene |volume=24 |issue= 13 |pages= 2204-17 |year= 2005 |pmid= 15735762 |doi= 10.1038/sj.onc.1208206 }}
+*{{cite journal  |vauthors=Pope SN, Lee IR |title=Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. |journal=J. Steroid Biochem. Mol. Biol. |volume=94 |issue= 1-3 |pages= 203–8 |year= 2005 |pmid= 15862967 |doi= 10.1016/j.jsbmb.2005.01.007 }}
-*{{cite journal  | author=Sun NN, Fastje CD, Wong SS, ''et al.'' |title=Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line. |journal=Toxicology and industrial health |volume=19 |issue= 7-10 |pages= 157-63 |year= 2005 |pmid= 15747776 |doi=  }}
-*{{cite journal  | author=Pope SN, Lee IR |title=Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. |journal=J. Steroid Biochem. Mol. Biol. |volume=94 |issue= 1-3 |pages= 203-8 |year= 2005 |pmid= 15862967 |doi= 10.1016/j.jsbmb.2005.01.007 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=4495}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+[[Category:Human proteins]]
-{{protein-stub}}
+{{gene-16-stub}}
-{{WikiDoc Sources}}

Metallothionein 1G: Difference between revisions

Revision as of 21:34, 4 September 2017

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